Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Galantamine> ?p ?o }
- Galantamine abstract "Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, in particular those of vascular origin. It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil), Leucojum aestivum (snowflake), and Lycoris including Lycoris radiata (Red Spider Lily).Studies of usage in modern medicine began in the Soviet Union in the 1950s. The active ingredient was extracted, identified, and studied, in particular in relation to its acetylcholinesterase (AChE)-inhibiting properties. The bulk of the work was carried out by Soviet pharmacologists M. D. Mashkovsky and R. P. Kruglikova–Lvova, beginning in 1951. The work of Mashkovsky and Kruglikova-Lvova was the first published work that demonstrated the AChE-inhibiting properties of galantamine.The first industrial process was developed in Bulgaria by prof. Paskov in 1959 (Nivalin, Sopharma) from a species traditionally used as a popular medicine in Eastern Europe, and, thus, the idea for developing a medicine from these species seems to be based on the local use (i.e., an ethnobotany-driven drug discovery).Galantamine has been used for decades in Eastern Europe and Russia for various indications such as treatment of myasthenia, myopathy, and sensory and motor dysfunction associated with disorders of the central nervous system. In the US, it is FDA approved for the treatment of Alzheimer's disease.It is available in both a prescription form and as an over the counter supplement.".
- Galantamine atcPrefix "N06".
- Galantamine atcSuffix "DA04".
- Galantamine bioavailability "80.0".
- Galantamine casNumber "357-70-0".
- Galantamine chEBI "42944".
- Galantamine drugbank "DB00674".
- Galantamine fdaUniiCode "0D3Q044KCA".
- Galantamine iupacName "(4aS,6R,8aS)- 5,6,9,10,11,12- hexahydro- 3-methoxy- 11-methyl- 4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin- 6-ol".
- Galantamine pubchem "9651".
- Galantamine thumbnail Galantamine.svg?width=300.
- Galantamine wikiPageExternalLink ocashort?id=1DX6.
- Galantamine wikiPageExternalLink AChE_inhibitors_and_substrates_%28Part_II%29.
- Galantamine wikiPageExternalLink quips?story=AChE.
- Galantamine wikiPageExternalLink www.pdbe.org.
- Galantamine wikiPageExternalLink 1dx6.
- Galantamine wikiPageExternalLink www.razadyneer.com.
- Galantamine wikiPageID "1214927".
- Galantamine wikiPageLength "18054".
- Galantamine wikiPageOutDegree "69".
- Galantamine wikiPageRevisionID "677829466".
- Galantamine wikiPageWikiLink 5-HT3_receptor.
- Galantamine wikiPageWikiLink Acetylcholine.
- Galantamine wikiPageWikiLink Acetylcholinesterase.
- Galantamine wikiPageWikiLink Acetylcholinesterase_inhibitor.
- Galantamine wikiPageWikiLink Adverse_drug_reaction.
- Galantamine wikiPageWikiLink Alkaloid.
- Galantamine wikiPageWikiLink Allosteric_modulator.
- Galantamine wikiPageWikiLink Alpha-3_beta-4_nicotinic_receptor.
- Galantamine wikiPageWikiLink Alpha-4_beta-2_nicotinic_receptor.
- Galantamine wikiPageWikiLink Alpha-7_nicotinic_receptor.
- Galantamine wikiPageWikiLink Alzheimers_disease.
- Galantamine wikiPageWikiLink Bioavailability.
- Galantamine wikiPageWikiLink Biological_half-life.
- Galantamine wikiPageWikiLink Blood_vessel.
- Galantamine wikiPageWikiLink Bradycardia.
- Galantamine wikiPageWikiLink Bulgaria.
- Galantamine wikiPageWikiLink CYP2D6.
- Galantamine wikiPageWikiLink CYP3A4.
- Galantamine wikiPageWikiLink Category:Acetylcholinesterase_inhibitors.
- Galantamine wikiPageWikiLink Category:Alcohols.
- Galantamine wikiPageWikiLink Category:Antidementia_agents.
- Galantamine wikiPageWikiLink Category:Benzazepines.
- Galantamine wikiPageWikiLink Category:Janssen_Pharmaceutica.
- Galantamine wikiPageWikiLink Category:Nootropics.
- Galantamine wikiPageWikiLink Category:Phenol_ethers.
- Galantamine wikiPageWikiLink Cholinesterase_inhibitor.
- Galantamine wikiPageWikiLink Competitive_inhibition.
- Galantamine wikiPageWikiLink Cytochrome_P450.
- Galantamine wikiPageWikiLink Cytochrome_P450_oxidase.
- Galantamine wikiPageWikiLink Daffodil.
- Galantamine wikiPageWikiLink Digestion.
- Galantamine wikiPageWikiLink Dimitar_Paskov.
- Galantamine wikiPageWikiLink Eastern_Europe.
- Galantamine wikiPageWikiLink Elimination_half-life.
- Galantamine wikiPageWikiLink Enzyme_inhibitor.
- Galantamine wikiPageWikiLink Ethnobotany.
- Galantamine wikiPageWikiLink Food_and_Drug_Administration.
- Galantamine wikiPageWikiLink Food_and_Drug_Administration_(United_States).
- Galantamine wikiPageWikiLink Galantamine.
- Galantamine wikiPageWikiLink Galanthus.
- Galantamine wikiPageWikiLink Galanthus_woronowii.
- Galantamine wikiPageWikiLink Gastrointestinal_tract.
- Galantamine wikiPageWikiLink Huperzine_A.
- Galantamine wikiPageWikiLink Insomnia.
- Galantamine wikiPageWikiLink Kidney.
- Galantamine wikiPageWikiLink Leucojum_aestivum.
- Galantamine wikiPageWikiLink Ligand_(biochemistry).
- Galantamine wikiPageWikiLink Liver.
- Galantamine wikiPageWikiLink Lucid_dream.
- Galantamine wikiPageWikiLink Lycoris_radiata.
- Galantamine wikiPageWikiLink Medicine.
- Galantamine wikiPageWikiLink Meditation.
- Galantamine wikiPageWikiLink Memory.
- Galantamine wikiPageWikiLink Mikhail_Davidovich_Mashkovsky.
- Galantamine wikiPageWikiLink Mild_cognitive_impairment.
- Galantamine wikiPageWikiLink Multi-infarct_dementia.
- Galantamine wikiPageWikiLink Narcissus_(plant).
- Galantamine wikiPageWikiLink Nicotinic_acetylcholine_receptor.
- Galantamine wikiPageWikiLink Nicotinic_acetylcholine_receptors.
- Galantamine wikiPageWikiLink Nivalin.
- Galantamine wikiPageWikiLink Nootropic.
- Galantamine wikiPageWikiLink Oneirogen.
- Galantamine wikiPageWikiLink Plasma_protein_binding.
- Galantamine wikiPageWikiLink Poor_metabolizer.
- Galantamine wikiPageWikiLink Risperidone.
- Galantamine wikiPageWikiLink Russia.
- Galantamine wikiPageWikiLink Snowdrop.
- Galantamine wikiPageWikiLink Sopharma.
- Galantamine wikiPageWikiLink Soviet_Union.
- Galantamine wikiPageWikiLink Syncope_(medicine).
- Galantamine wikiPageWikiLink Total_synthesis.
- Galantamine wikiPageWikiLink Vascular.
- Galantamine wikiPageWikiLink Vascular_dementia.
- Galantamine wikiPageWikiLink X-ray_crystallography.
- Galantamine wikiPageWikiLink Α3β4_nicotinic_receptor.
- Galantamine wikiPageWikiLink Α4β2_nicotinic_receptor.
- Galantamine wikiPageWikiLink Α7_nicotinic_acetylcholine_receptor.
- Galantamine wikiPageWikiLink Α6β4.
- Galantamine wikiPageWikiLinkText "Galantamine hydrobromide".