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- Galanin_receptor_2 abstract "Galanin receptor 2, (GAL2) is a G-protein coupled receptor encoded by the GALR2 gene.Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.".
- Galanin_receptor_2 entrezgene "8811".
- Galanin_receptor_2 wikiPageExternalLink ReceptorDisplayForward?receptorID=2982.
- Galanin_receptor_2 wikiPageID "14428986".
- Galanin_receptor_2 wikiPageLength "5113".
- Galanin_receptor_2 wikiPageOutDegree "5".
- Galanin_receptor_2 wikiPageRevisionID "678818431".
- Galanin_receptor_2 wikiPageWikiLink Category:G_protein_coupled_receptors.
- Galanin_receptor_2 wikiPageWikiLink G-protein_coupled_receptor.
- Galanin_receptor_2 wikiPageWikiLink G_protein–coupled_receptor.
- Galanin_receptor_2 wikiPageWikiLink Galanin_receptor.
- Galanin_receptor_2 wikiPageWikiLink Gene.
- Galanin_receptor_2 wikiPageWikiLink Genes,_Brain_and_Behavior.
- Galanin_receptor_2 wikiPageWikiLinkText "GAL-R2".
- Galanin_receptor_2 wikiPageWikiLinkText "Galanin receptor 2".
- Galanin_receptor_2 wikiPageWikiLinkText "galanin receptor 2".
- Galanin_receptor_2 hasPhotoCollection Galanin_receptor_2.
- Galanin_receptor_2 requireManualInspection "no".
- Galanin_receptor_2 summaryText "Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway , in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.".
- Galanin_receptor_2 updateCitations "yes".
- Galanin_receptor_2 updatePage "yes".
- Galanin_receptor_2 updateProteinBox "yes".
- Galanin_receptor_2 updateSummary "yes".
- Galanin_receptor_2 wikiPageUsesTemplate Template:Cite_web.
- Galanin_receptor_2 wikiPageUsesTemplate Template:G_protein-coupled_receptors.
- Galanin_receptor_2 wikiPageUsesTemplate Template:NLM_content.
- Galanin_receptor_2 wikiPageUsesTemplate Template:Neuropeptidergics.
- Galanin_receptor_2 wikiPageUsesTemplate Template:PBB.
- Galanin_receptor_2 wikiPageUsesTemplate Template:PBB_Controls.
- Galanin_receptor_2 wikiPageUsesTemplate Template:PBB_Further_reading.
- Galanin_receptor_2 wikiPageUsesTemplate Template:PBB_Summary.
- Galanin_receptor_2 wikiPageUsesTemplate Template:Refbegin.
- Galanin_receptor_2 wikiPageUsesTemplate Template:Refend.
- Galanin_receptor_2 wikiPageUsesTemplate Template:Reflist.
- Galanin_receptor_2 wikiPageUsesTemplate Template:Transmembranereceptor-stub.
- Galanin_receptor_2 subject Category:G_protein_coupled_receptors.
- Galanin_receptor_2 hypernym Protein.
- Galanin_receptor_2 type Article.
- Galanin_receptor_2 type Biomolecule.
- Galanin_receptor_2 type Protein.
- Galanin_receptor_2 type Article.
- Galanin_receptor_2 type Institute.
- Galanin_receptor_2 type Source.
- Galanin_receptor_2 type Thing.
- Galanin_receptor_2 type Q206229.
- Galanin_receptor_2 type Q8054.
- Galanin_receptor_2 comment "Galanin receptor 2, (GAL2) is a G-protein coupled receptor encoded by the GALR2 gene.Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility.".
- Galanin_receptor_2 label "Galanin receptor 2".
- Galanin_receptor_2 sameAs m.03d37j5.
- Galanin_receptor_2 sameAs Galaninski_receptor_2.
- Galanin_receptor_2 sameAs Galaninski_receptor_2.
- Galanin_receptor_2 sameAs Q5517942.
- Galanin_receptor_2 sameAs Q5517942.
- Galanin_receptor_2 wasDerivedFrom Galanin_receptor_2?oldid=678818431.
- Galanin_receptor_2 isPrimaryTopicOf Galanin_receptor_2.