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- Gabapentinoid abstract "Gabapentinoids are 3-substituted derivatives of the neurotransmitter γ-aminobutyric acid (GABA) which selectively block α2δ subunit-containing voltage-dependent calcium channels (VGCCs). Clinically-used gabapentinoids include gabapentin (Neurontin) and pregabalin (Lyrica), as well as a gabapentin prodrug, gabapentin enacarbil (Horizant). Another analogue mirogabalin is in clinical trials but has not yet been approved. Other compounds from this family used in research but not developed for medical use include atagabalin, 4-methylpregabalin and PD-217,014. Gabapentinoids are used clinically in the treatment of conditions including epilepsy, neuropathic pain, fibromyalgia, anxiety, and restless legs syndrome, among others.Recently, phenibut has been found to bind to and block α2δ-containing VGCCs with an affinity exceeding that of its other actions.".
- Gabapentinoid wikiPageID "43348559".
- Gabapentinoid wikiPageLength "3864".
- Gabapentinoid wikiPageOutDegree "24".
- Gabapentinoid wikiPageRevisionID "679852791".
- Gabapentinoid wikiPageWikiLink 4-Methylpregabalin.
- Gabapentinoid wikiPageWikiLink 4-methylpregabalin.
- Gabapentinoid wikiPageWikiLink Anxiety.
- Gabapentinoid wikiPageWikiLink Atagabalin.
- Gabapentinoid wikiPageWikiLink Category:Amino_acids.
- Gabapentinoid wikiPageWikiLink Category:Analgesics.
- Gabapentinoid wikiPageWikiLink Category:Anticonvulsants.
- Gabapentinoid wikiPageWikiLink Category:Anxiolytics.
- Gabapentinoid wikiPageWikiLink Category:GABA_analogues.
- Gabapentinoid wikiPageWikiLink Epilepsy.
- Gabapentinoid wikiPageWikiLink Fibromyalgia.
- Gabapentinoid wikiPageWikiLink Gabapentin.
- Gabapentinoid wikiPageWikiLink Gabapentin_enacarbil.
- Gabapentinoid wikiPageWikiLink Gamma-Aminobutyric_acid.
- Gabapentinoid wikiPageWikiLink Ligand_(biochemistry).
- Gabapentinoid wikiPageWikiLink Mirogabalin.
- Gabapentinoid wikiPageWikiLink Neuropathic_pain.
- Gabapentinoid wikiPageWikiLink Neurotransmitter.
- Gabapentinoid wikiPageWikiLink PD-217,014.
- Gabapentinoid wikiPageWikiLink Phenibut.
- Gabapentinoid wikiPageWikiLink Pregabalin.
- Gabapentinoid wikiPageWikiLink Prodrug.
- Gabapentinoid wikiPageWikiLink Restless_legs_syndrome.
- Gabapentinoid wikiPageWikiLink Voltage-dependent_calcium_channel.
- Gabapentinoid wikiPageWikiLink Γ-aminobutyric_acid.
- Gabapentinoid wikiPageWikiLinkText "Gabapentinoid".
- Gabapentinoid wikiPageWikiLinkText "gabapentinoid".
- Gabapentinoid hasPhotoCollection Gabapentinoid.
- Gabapentinoid wikiPageUsesTemplate Template:Anticonvulsants.
- Gabapentinoid wikiPageUsesTemplate Template:Anxiolytics.
- Gabapentinoid wikiPageUsesTemplate Template:Channel_blockers.
- Gabapentinoid wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Gabapentinoid wikiPageUsesTemplate Template:Neuropathic_pain_and_fibromyalgia_pharmacotherapies.
- Gabapentinoid wikiPageUsesTemplate Template:Reflist.
- Gabapentinoid subject Category:Amino_acids.
- Gabapentinoid subject Category:Analgesics.
- Gabapentinoid subject Category:Anticonvulsants.
- Gabapentinoid subject Category:Anxiolytics.
- Gabapentinoid subject Category:GABA_analogues.
- Gabapentinoid hypernym Derivatives.
- Gabapentinoid type ChemicalCompound.
- Gabapentinoid comment "Gabapentinoids are 3-substituted derivatives of the neurotransmitter γ-aminobutyric acid (GABA) which selectively block α2δ subunit-containing voltage-dependent calcium channels (VGCCs). Clinically-used gabapentinoids include gabapentin (Neurontin) and pregabalin (Lyrica), as well as a gabapentin prodrug, gabapentin enacarbil (Horizant). Another analogue mirogabalin is in clinical trials but has not yet been approved.".
- Gabapentinoid label "Gabapentinoid".
- Gabapentinoid sameAs m.011c9c7t.
- Gabapentinoid sameAs Q18207292.
- Gabapentinoid sameAs Q18207292.
- Gabapentinoid wasDerivedFrom Gabapentinoid?oldid=679852791.
- Gabapentinoid isPrimaryTopicOf Gabapentinoid.