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- G_protein-coupled_receptor_kinase abstract "G protein-coupled receptor kinases (GRKs, GPCRKs) are a family of protein kinases that regulate the activity of G protein-coupled receptors (GPCRs) by phosphorylating their intracellular domains after their associated G proteins have been released and activated. The phosphorylated serine and threonine residues act as binding sites for arrestin proteins that prevent the reassociation of the G proteins with their receptors, thereby preventing reactivation of the signaling pathway.GRKs regulate also cellular responses independent of their kinase activity. In particular, G protein-coupled receptor kinase 2 interacts with a diverse repertoire of non-GPCR substrates.GRK1 is involved with Rhodopsin phosphorlylation and deactivation. Defects in GRK1 result in Oguchi disease 2.".
- G_protein-coupled_receptor_kinase ecNumber "2.7.11.16".
- G_protein-coupled_receptor_kinase thumbnail Gprotein-coupled_receptor_kinase.png?width=300.
- G_protein-coupled_receptor_kinase wikiPageExternalLink books?id=jtSqgZXIVt4C&pg=PA186.
- G_protein-coupled_receptor_kinase wikiPageExternalLink books?id=sW2SY9zzydMC&pg=PA149.
- G_protein-coupled_receptor_kinase wikiPageID "5669787".
- G_protein-coupled_receptor_kinase wikiPageLength "5797".
- G_protein-coupled_receptor_kinase wikiPageOutDegree "39".
- G_protein-coupled_receptor_kinase wikiPageRevisionID "661029138".
- G_protein-coupled_receptor_kinase wikiPageWikiLink Adenosine_triphosphate.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Arrestin.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Beta_adrenergic_receptor_kinase.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Beta_adrenergic_receptor_kinase-2.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Binding_site.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Category:EC_2.7.11.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Category:Protein_kinases.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Cone_opsin.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Core_temperature.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Dopaminergic.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Downregulation_and_upregulation.
- G_protein-coupled_receptor_kinase wikiPageWikiLink GRK4.
- G_protein-coupled_receptor_kinase wikiPageWikiLink GRK5.
- G_protein-coupled_receptor_kinase wikiPageWikiLink GRK6.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_1.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_2.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_3.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_4.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_5.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_6.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptor_kinase_7.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein-coupled_receptors.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_proteins.
- G_protein-coupled_receptor_kinase wikiPageWikiLink G_protein–coupled_receptor.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Gene.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Human_body_temperature.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Intracellular.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Kidney.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Kinase.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Knockout_mice.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Knockout_mouse.
- G_protein-coupled_receptor_kinase wikiPageWikiLink OMIM.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Online_Mendelian_Inheritance_in_Man.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Phosphorylation.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Photopsin.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Protein_family.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Protein_kinase.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Rhodopsin_kinase.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Serine.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Signal_transduction.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Threonine.
- G_protein-coupled_receptor_kinase wikiPageWikiLink Tubule.
- G_protein-coupled_receptor_kinase wikiPageWikiLinkText "G protein-coupled receptor kinase".
- G_protein-coupled_receptor_kinase wikiPageWikiLinkText "GPCR-Regulating Kinases".
- G_protein-coupled_receptor_kinase wikiPageWikiLinkText "GRKs".
- G_protein-coupled_receptor_kinase caption "Crystal structure of G protein coupled receptor kinase 1 bound to ATP.".
- G_protein-coupled_receptor_kinase ecNumber "2.7".
- G_protein-coupled_receptor_kinase goCode "4703".
- G_protein-coupled_receptor_kinase hasPhotoCollection G_protein-coupled_receptor_kinase.
- G_protein-coupled_receptor_kinase iubmbEcNumber "2".
- G_protein-coupled_receptor_kinase name "G protein-coupled receptor kinase".
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Cite_book.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Cite_journal.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Enzyme.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Gene.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:OMIM2.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Refbegin.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Refend.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Reflist.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate threonine-specific_protein_kinases.
- G_protein-coupled_receptor_kinase wikiPageUsesTemplate Template:Transferase-stub.
- G_protein-coupled_receptor_kinase subject Category:EC_2.7.11.
- G_protein-coupled_receptor_kinase subject Category:Protein_kinases.
- G_protein-coupled_receptor_kinase hypernym Family.
- G_protein-coupled_receptor_kinase type Biomolecule.
- G_protein-coupled_receptor_kinase type Enzyme.
- G_protein-coupled_receptor_kinase type Thing.
- G_protein-coupled_receptor_kinase type Q206229.
- G_protein-coupled_receptor_kinase type Q8047.
- G_protein-coupled_receptor_kinase comment "G protein-coupled receptor kinases (GRKs, GPCRKs) are a family of protein kinases that regulate the activity of G protein-coupled receptors (GPCRs) by phosphorylating their intracellular domains after their associated G proteins have been released and activated.".
- G_protein-coupled_receptor_kinase label "G protein-coupled receptor kinase".
- G_protein-coupled_receptor_kinase sameAs Gprk2.
- G_protein-coupled_receptor_kinase sameAs m.0dz7yb.
- G_protein-coupled_receptor_kinase sameAs GRK-киназы.
- G_protein-coupled_receptor_kinase sameAs G_protein_spregnuti_receptor_kinaza.
- G_protein-coupled_receptor_kinase sameAs G_protein_spregnuti_receptor_kinaza.
- G_protein-coupled_receptor_kinase sameAs Q4355943.
- G_protein-coupled_receptor_kinase sameAs Q4355943.
- G_protein-coupled_receptor_kinase wasDerivedFrom G_protein-coupled_receptor_kinase?oldid=661029138.
- G_protein-coupled_receptor_kinase depiction Gprotein-coupled_receptor_kinase.png.
- G_protein-coupled_receptor_kinase isPrimaryTopicOf G_protein-coupled_receptor_kinase.
- G_protein-coupled_receptor_kinase name "G protein-coupled receptor kinase".