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- GL-ONC1 abstract "GL-ONC1 is an investigational therapeutic product consisting of the clinical grade formulation of the laboratory strain GLV-1h68, an oncolytic virus developed by Genelux Corporation. GL-ONC1 is currently under evaluation in Phase I/II human clinical trials in the United States and Europe.GL-ONC1 is an attenuated vaccinia virus (Lister strain) that causes regression and elimination of a wide range of solid tumors in preclincal mouse models. GLV-1h68 (GL-ONC1) was generated by insertion of three expression cassettes (encoding Renilla luciferase-Aequorea green fluorescent protein fusion, beta-galactosidase, and beta-glucuronidase) replacing the F14.5L, J2R (encoding thymidine kinase) and A56R (encoding hemagglutinin) loci of the parental viral Lister strain genome, respectively. The oncolytic virus specifically infects and kills tumor cells which leads to oncolysis, which is thought to trigger an anti-tumor immune response.".
- GL-ONC1 wikiPageExternalLink default.aspx.
- GL-ONC1 wikiPageExternalLink www.genelux.com.
- GL-ONC1 wikiPageExternalLink Homepage.html.
- GL-ONC1 wikiPageExternalLink home.aspx.
- GL-ONC1 wikiPageExternalLink www.mskcc.org.
- GL-ONC1 wikiPageID "47161484".
- GL-ONC1 wikiPageLength "5801".
- GL-ONC1 wikiPageOutDegree "23".
- GL-ONC1 wikiPageRevisionID "678817239".
- GL-ONC1 wikiPageWikiLink Aequorea.
- GL-ONC1 wikiPageWikiLink Beta-galactosidase.
- GL-ONC1 wikiPageWikiLink Beta-glucuronidase.
- GL-ONC1 wikiPageWikiLink Breast_cancer.
- GL-ONC1 wikiPageWikiLink Category:Experimental_cancer_treatments.
- GL-ONC1 wikiPageWikiLink Category:Virotherapy.
- GL-ONC1 wikiPageWikiLink Genelux_Corporation.
- GL-ONC1 wikiPageWikiLink Green_fluorescent_protein.
- GL-ONC1 wikiPageWikiLink Intraperitoneal.
- GL-ONC1 wikiPageWikiLink Luciferase.
- GL-ONC1 wikiPageWikiLink Lysis.
- GL-ONC1 wikiPageWikiLink Malignant_pleural_effusion.
- GL-ONC1 wikiPageWikiLink Memorial_Sloan_Kettering_Cancer_Center.
- GL-ONC1 wikiPageWikiLink Mesothelioma.
- GL-ONC1 wikiPageWikiLink Moores_UC_San_Diego_Cancer_Center.
- GL-ONC1 wikiPageWikiLink Non-small-cell_lung_carcinoma.
- GL-ONC1 wikiPageWikiLink Non-small_cell_lung_cancer.
- GL-ONC1 wikiPageWikiLink Oncolysis.
- GL-ONC1 wikiPageWikiLink Oncolytic_virus.
- GL-ONC1 wikiPageWikiLink Peritoneal_carcinomatosis.
- GL-ONC1 wikiPageWikiLink Peritoneum.
- GL-ONC1 wikiPageWikiLink Renilla.
- GL-ONC1 wikiPageWikiLink Royal_Marsden_Hospital.
- GL-ONC1 wikiPageWikiLink Sea_pansy.
- GL-ONC1 wikiPageWikiLink The_Royal_Marsden_NHS_Foundation_Trust.
- GL-ONC1 wikiPageWikiLink University_of_Tübingen.
- GL-ONC1 wikiPageWikiLink Vaccinia.
- GL-ONC1 wikiPageWikiLink Vaccinia_virus.
- GL-ONC1 wikiPageWikiLink Category:Oncolytic_virus.
- GL-ONC1 wikiPageWikiLinkText "GL-ONC1".
- GL-ONC1 hasPhotoCollection GL-ONC1.
- GL-ONC1 wikiPageUsesTemplate Template:Reflist.
- GL-ONC1 subject Category:Experimental_cancer_treatments.
- GL-ONC1 subject Category:Virotherapy.
- GL-ONC1 subject Category:Oncolytic_virus.
- GL-ONC1 hypernym Product.
- GL-ONC1 type Software.
- GL-ONC1 comment "GL-ONC1 is an investigational therapeutic product consisting of the clinical grade formulation of the laboratory strain GLV-1h68, an oncolytic virus developed by Genelux Corporation. GL-ONC1 is currently under evaluation in Phase I/II human clinical trials in the United States and Europe.GL-ONC1 is an attenuated vaccinia virus (Lister strain) that causes regression and elimination of a wide range of solid tumors in preclincal mouse models.".
- GL-ONC1 label "GL-ONC1".
- GL-ONC1 wasDerivedFrom GL-ONC1?oldid=678817239.
- GL-ONC1 isPrimaryTopicOf GL-ONC1.