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- GHRP-6 abstract "Growth hormone-releasing peptide 6 (GHRP-6) (developmental code name SKF-110679), also known as growth hormone-releasing hexapeptide, is one of several synthetic met-enkephalin analogues that include unnatural D-amino acids, were developed for their growth hormone-releasing activity and are called growth hormone secretagogues. They lack opioid activity but are potent stimulators of growth hormone (GH) release. These secretagogues are distinct from growth hormone releasing hormone (GHRH) in that they share no sequence relation and derive their function through activation of a completely different receptor. This receptor was originally called the growth hormone secretagogue receptor (GHSR), but due to subsequent discoveries, the hormone ghrelin is now considered the receptor's natural endogenous ligand, and it has been renamed as the ghrelin receptor. Therefore, these GHSR agonists act as synthetic ghrelin mimetics.It has been discovered that when GHRP-6 and insulin are administered simultaneously, GH response to GHRP-6 is increased (1). However, the consumption of carbohydrates and/or dietary fats, around the administration window of GH secretagogues significantly blunts the GH release. A recent study in normal mice showed significant differences in body composition, muscle growth, glucose metabolism, memory and cardiac function in the mice being administered the GHRP-6 (2). There are still many questions regarding this fairly new compound, scientists are hoping to gain a better clinical understanding of the peptide through further research over the next few years.GH secretagogues differ from exogenous rHGH in their effects primarily because endogenous GH contains all five isoforms of growth hormone, whereas exogenous GH contains only the 20 kilodalton isoform. Different isoforms affect tissues in discreet ways that the 20 kDa isoform cannot. Administration of GH secretagogues causes a pulse-release of GH from the pituitary which is cleared from the body within a few hours. This does not significantly raise plasma insulin-like growth factor 1 (IGF-1) levels.".
- GHRP-6 atcPrefix "None".
- GHRP-6 casNumber "87616-84-0".
- GHRP-6 iupacName "L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-Lysinamide".
- GHRP-6 pubchem "5486806".
- GHRP-6 thumbnail GHRP-6.png?width=300.
- GHRP-6 wikiPageExternalLink we-need-an-advocate-against-asadas-power-in-doping-control-12119.
- GHRP-6 wikiPageID "11546264".
- GHRP-6 wikiPageLength "7716".
- GHRP-6 wikiPageOutDegree "32".
- GHRP-6 wikiPageRevisionID "677858174".
- GHRP-6 wikiPageWikiLink Amino_acid.
- GHRP-6 wikiPageWikiLink Amino_acid_sequence.
- GHRP-6 wikiPageWikiLink Anamorelin.
- GHRP-6 wikiPageWikiLink Capromorelin.
- GHRP-6 wikiPageWikiLink Category:Ghrelin_receptor_agonists.
- GHRP-6 wikiPageWikiLink Category:Growth_hormone_secretagogues.
- GHRP-6 wikiPageWikiLink Category:Hormonal_agents.
- GHRP-6 wikiPageWikiLink Category:Peptides.
- GHRP-6 wikiPageWikiLink Endogenous.
- GHRP-6 wikiPageWikiLink Endogeny_(biology).
- GHRP-6 wikiPageWikiLink Examorelin.
- GHRP-6 wikiPageWikiLink Ghrelin.
- GHRP-6 wikiPageWikiLink Growth-hormone-releasing_hormone.
- GHRP-6 wikiPageWikiLink Growth_hormone.
- GHRP-6 wikiPageWikiLink Growth_hormone_releasing_hormone.
- GHRP-6 wikiPageWikiLink Growth_hormone_secretagogue.
- GHRP-6 wikiPageWikiLink Growth_hormone_secretagogue_receptor.
- GHRP-6 wikiPageWikiLink Ibutamoren.
- GHRP-6 wikiPageWikiLink Insulin.
- GHRP-6 wikiPageWikiLink Insulin-like_growth_factor_1.
- GHRP-6 wikiPageWikiLink Ipamorelin.
- GHRP-6 wikiPageWikiLink Ligand_(biochemistry).
- GHRP-6 wikiPageWikiLink Macimorelin.
- GHRP-6 wikiPageWikiLink Met-enkephalin.
- GHRP-6 wikiPageWikiLink Opioid.
- GHRP-6 wikiPageWikiLink Organic_compound.
- GHRP-6 wikiPageWikiLink Peptide_sequence.
- GHRP-6 wikiPageWikiLink Pralmorelin.
- GHRP-6 wikiPageWikiLink Receptor_(biochemistry).
- GHRP-6 wikiPageWikiLink Relamorelin.
- GHRP-6 wikiPageWikiLink SM-130,686.
- GHRP-6 wikiPageWikiLink Secretagogue.
- GHRP-6 wikiPageWikiLink Structural_analog.
- GHRP-6 wikiPageWikiLink Tabimorelin.
- GHRP-6 wikiPageWikiLinkText "GHRP-6 (SKF-110679)".
- GHRP-6 wikiPageWikiLinkText "GHRP-6".
- GHRP-6 atcPrefix "None".
- GHRP-6 c "46".
- GHRP-6 casNumber "87616".
- GHRP-6 chemspiderid "26333269".
- GHRP-6 eliminationHalfLife "9000.0".
- GHRP-6 h "56".
- GHRP-6 hasPhotoCollection GHRP-6.
- GHRP-6 inchi "1".
- GHRP-6 inchikey "WZHKXNSOCOQYQX-KAGZITNABO".
- GHRP-6 iupacName "L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-Lysinamide".
- GHRP-6 molecularWeight "873.014".
- GHRP-6 n "12".
- GHRP-6 o "6".
- GHRP-6 pubchem "5486806".
- GHRP-6 smiles "C[C@@H]NC[C@@H]NC[C@H]N".
- GHRP-6 stdinchi "1".
- GHRP-6 stdinchikey "WZHKXNSOCOQYQX-KAGZITNASA-N".
- GHRP-6 verifiedfields "changed".
- GHRP-6 verifiedrevid "428750426".
- GHRP-6 watchedfields "changed".
- GHRP-6 wikiPageUsesTemplate Template:Citation_needed.
- GHRP-6 wikiPageUsesTemplate Template:Cite_journal.
- GHRP-6 wikiPageUsesTemplate Template:Drugbox.
- GHRP-6 wikiPageUsesTemplate Template:More_footnotes.
- GHRP-6 wikiPageUsesTemplate Template:Multiple_issues.
- GHRP-6 wikiPageUsesTemplate Template:Neuropeptidergics.
- GHRP-6 wikiPageUsesTemplate Template:Reflist.
- GHRP-6 wikiPageUsesTemplate Template:Systemic-hormonal-drug-stub.
- GHRP-6 subject Category:Ghrelin_receptor_agonists.
- GHRP-6 subject Category:Growth_hormone_secretagogues.
- GHRP-6 subject Category:Hormonal_agents.
- GHRP-6 subject Category:Peptides.
- GHRP-6 type ChemicalSubstance.
- GHRP-6 type Drug.
- GHRP-6 type ChemicalObject.
- GHRP-6 type Thing.
- GHRP-6 type Q8386.
- GHRP-6 comment "Growth hormone-releasing peptide 6 (GHRP-6) (developmental code name SKF-110679), also known as growth hormone-releasing hexapeptide, is one of several synthetic met-enkephalin analogues that include unnatural D-amino acids, were developed for their growth hormone-releasing activity and are called growth hormone secretagogues. They lack opioid activity but are potent stimulators of growth hormone (GH) release.".
- GHRP-6 label "GHRP-6".
- GHRP-6 sameAs m.02rhn4d.
- GHRP-6 sameAs GHRP.
- GHRP-6 sameAs Heksapeptid_oslobađanja_hormona_rasta.
- GHRP-6 sameAs Heksapeptid_oslobađanja_hormona_rasta.
- GHRP-6 sameAs Q5611751.
- GHRP-6 sameAs Q5611751.
- GHRP-6 wasDerivedFrom GHRP-6?oldid=677858174.
- GHRP-6 depiction GHRP-6.png.
- GHRP-6 isPrimaryTopicOf GHRP-6.