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- Futile_cycle abstract "A futile cycle, also known as a substrate cycle, occurs when two metabolic pathways run simultaneously in opposite directions and have no overall effect other than to dissipate energy in the form of heat. For example, if glycolysis and gluconeogenesis were to be active at the same time, glucose would be converted to pyruvate by glycolysis and then converted back to glucose by gluconeogenesis, with an overall consumption of ATP. Futile cycles may have a role in metabolic regulation, where a futile cycle would be a system oscillating between two states and very sensitive to small changes in the activity of any of the enzymes involved. The cycle does generate heat, and may be used to maintain thermal homeostasis, for example in the brown adipose tissue of young mammals, or to generate heat rapidly, for example in insect flight muscles and in hibernating animals during periodical arousal from torpor.It has been reported that the glucose metabolism substrate cycle is not a futile cycle but a regulatory process. For example, when energy is suddenly needed, ATP is replaced by AMP, a much more reactive adenine.".
- Futile_cycle thumbnail Biochem_reaction_arrow_forward_NNNN_horiz_med.png?width=300.
- Futile_cycle wikiPageID "10059553".
- Futile_cycle wikiPageLength "3727".
- Futile_cycle wikiPageOutDegree "27".
- Futile_cycle wikiPageRevisionID "605217848".
- Futile_cycle wikiPageWikiLink Adenosine_triphosphate.
- Futile_cycle wikiPageWikiLink Brown_adipose_tissue.
- Futile_cycle wikiPageWikiLink Catalysis.
- Futile_cycle wikiPageWikiLink Category:Glycolysis.
- Futile_cycle wikiPageWikiLink Category:Metabolism.
- Futile_cycle wikiPageWikiLink Dissipation.
- Futile_cycle wikiPageWikiLink Enzyme.
- Futile_cycle wikiPageWikiLink Gluconeogenesis.
- Futile_cycle wikiPageWikiLink Glucose.
- Futile_cycle wikiPageWikiLink Glycolysis.
- Futile_cycle wikiPageWikiLink Heat.
- Futile_cycle wikiPageWikiLink Homeostasis.
- Futile_cycle wikiPageWikiLink Hydrolysis.
- Futile_cycle wikiPageWikiLink Insect.
- Futile_cycle wikiPageWikiLink Mammal.
- Futile_cycle wikiPageWikiLink Metabolic_pathway.
- Futile_cycle wikiPageWikiLink Phosphofructokinase_1.
- Futile_cycle wikiPageWikiLink Pyruvate.
- Futile_cycle wikiPageWikiLink Pyruvic_acid.
- Futile_cycle wikiPageWikiLink Torpor.
- Futile_cycle wikiPageWikiLink File:Biochem_reaction_arrow_forward_NNNN_horiz_med.png.
- Futile_cycle wikiPageWikiLinkText "Futile cycle".
- Futile_cycle wikiPageWikiLinkText "futile cycle".
- Futile_cycle hasPhotoCollection Futile_cycle.
- Futile_cycle wikiPageUsesTemplate Template:Biochem-stub.
- Futile_cycle wikiPageUsesTemplate Template:MeshName.
- Futile_cycle wikiPageUsesTemplate Template:Reflist.
- Futile_cycle subject Category:Glycolysis.
- Futile_cycle subject Category:Metabolism.
- Futile_cycle type Article.
- Futile_cycle type Article.
- Futile_cycle type Pathway.
- Futile_cycle type Process.
- Futile_cycle comment "A futile cycle, also known as a substrate cycle, occurs when two metabolic pathways run simultaneously in opposite directions and have no overall effect other than to dissipate energy in the form of heat. For example, if glycolysis and gluconeogenesis were to be active at the same time, glucose would be converted to pyruvate by glycolysis and then converted back to glucose by gluconeogenesis, with an overall consumption of ATP.".
- Futile_cycle label "Futile cycle".
- Futile_cycle sameAs Substratzyklus.
- Futile_cycle sameAs Substraattikierto.
- Futile_cycle sameAs 無益回路.
- Futile_cycle sameAs m.02q0hcb.
- Futile_cycle sameAs Q905391.
- Futile_cycle sameAs Q905391.
- Futile_cycle wasDerivedFrom Futile_cycle?oldid=605217848.
- Futile_cycle depiction Biochem_reaction_arrow_forward_NNNN_horiz_med.png.
- Futile_cycle isPrimaryTopicOf Futile_cycle.