Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Frameshift_mutation> ?p ?o }
- Frameshift_mutation abstract "A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. Due to the triplet nature of gene expression by codons, the insertion or deletion can change the reading frame (the grouping of the codons), resulting in a completely different translation from the original. The earlier in the sequence the deletion or insertion occurs, the more altered the protein. A frameshift mutation is not the same as a single-nucleotide polymorphism in which a nucleotide is replaced, rather than inserted or deleted. A frameshift mutation will in general cause the reading of the codons after the mutation to code for different amino acids. The frameshift mutation will also alter the first stop codon ("UAA", "UGA" or "UAG") encountered in the sequence. The polypeptide being created could be abnormally short or abnormally long, and will most likely not be functional.Frameshift mutations are apparent in severe genetic diseases such as Tay-Sachs disease and Cystic Fibrosis; they increase susceptibility to certain cancers and classes of familial hypercholesterolaemia; in 1997, a frameshift mutation was linked to resistance to infection by the HIV retrovirus. Frameshift mutations have been proposed as a source of biological novelty, as with the alleged creation of nylonase, however, this interpretation is controversial. A study by Negoro et al (2006) found that a frameshift mutation was unlikely to have been the cause and that rather a two amino acid substitution in the catalytic cleft of an ancestral esterase amplified Ald-hydrolytic activity.".
- Frameshift_mutation thumbnail Frameshift_mutation.jpg?width=300.
- Frameshift_mutation wikiPageExternalLink apr04.html.
- Frameshift_mutation wikiPageExternalLink path.
- Frameshift_mutation wikiPageExternalLink fasta_www.cgi?rm=select&pgm=fy.
- Frameshift_mutation wikiPageExternalLink index.htm.
- Frameshift_mutation wikiPageExternalLink index.php.
- Frameshift_mutation wikiPageExternalLink SNP.
- Frameshift_mutation wikiPageID "610997".
- Frameshift_mutation wikiPageLength "34419".
- Frameshift_mutation wikiPageOutDegree "122".
- Frameshift_mutation wikiPageRevisionID "681945930".
- Frameshift_mutation wikiPageWikiLink Amino_acid.
- Frameshift_mutation wikiPageWikiLink Amino_acids.
- Frameshift_mutation wikiPageWikiLink Apoptosis.
- Frameshift_mutation wikiPageWikiLink Ashkenazi.
- Frameshift_mutation wikiPageWikiLink Ashkenazi_Jews.
- Frameshift_mutation wikiPageWikiLink Bacteria.
- Frameshift_mutation wikiPageWikiLink CCR5.
- Frameshift_mutation wikiPageWikiLink Cancer.
- Frameshift_mutation wikiPageWikiLink Cancers.
- Frameshift_mutation wikiPageWikiLink Catalysis.
- Frameshift_mutation wikiPageWikiLink Catalytic.
- Frameshift_mutation wikiPageWikiLink Category:Mutation.
- Frameshift_mutation wikiPageWikiLink Cell_(biology).
- Frameshift_mutation wikiPageWikiLink Cloning.
- Frameshift_mutation wikiPageWikiLink Codon.
- Frameshift_mutation wikiPageWikiLink Colorectal.
- Frameshift_mutation wikiPageWikiLink Crohns_Disease.
- Frameshift_mutation wikiPageWikiLink Crohns_disease.
- Frameshift_mutation wikiPageWikiLink Cystic_Fibrosis.
- Frameshift_mutation wikiPageWikiLink Cystic_fibrosis.
- Frameshift_mutation wikiPageWikiLink Cytosine.
- Frameshift_mutation wikiPageWikiLink DNA.
- Frameshift_mutation wikiPageWikiLink DNA_mismatch_repair.
- Frameshift_mutation wikiPageWikiLink DNA_replication.
- Frameshift_mutation wikiPageWikiLink Deletion_(genetics).
- Frameshift_mutation wikiPageWikiLink E._coli.
- Frameshift_mutation wikiPageWikiLink EF-Tu.
- Frameshift_mutation wikiPageWikiLink Emory_University.
- Frameshift_mutation wikiPageWikiLink Enzyme.
- Frameshift_mutation wikiPageWikiLink Enzymes.
- Frameshift_mutation wikiPageWikiLink Escherichia_coli.
- Frameshift_mutation wikiPageWikiLink Esterase.
- Frameshift_mutation wikiPageWikiLink Exon.
- Frameshift_mutation wikiPageWikiLink Exonuclease.
- Frameshift_mutation wikiPageWikiLink Experiment.
- Frameshift_mutation wikiPageWikiLink Familial_hypercholesterolaemia.
- Frameshift_mutation wikiPageWikiLink Familial_hypercholesterolemia.
- Frameshift_mutation wikiPageWikiLink File:Translation-genetics.png.
- Frameshift_mutation wikiPageWikiLink Fluorescence.
- Frameshift_mutation wikiPageWikiLink Frameshift.
- Frameshift_mutation wikiPageWikiLink Francis_Crick.
- Frameshift_mutation wikiPageWikiLink Gene_expression.
- Frameshift_mutation wikiPageWikiLink Gene_insertion.
- Frameshift_mutation wikiPageWikiLink Genetic_code.
- Frameshift_mutation wikiPageWikiLink Genetic_deletion.
- Frameshift_mutation wikiPageWikiLink Genetic_mutation.
- Frameshift_mutation wikiPageWikiLink Genetic_recombination.
- Frameshift_mutation wikiPageWikiLink Genome.
- Frameshift_mutation wikiPageWikiLink Guanosine_triphosphate.
- Frameshift_mutation wikiPageWikiLink Guide_RNA.
- Frameshift_mutation wikiPageWikiLink Huntingtons_disease.
- Frameshift_mutation wikiPageWikiLink Hypertrophic_cardiomyopathy.
- Frameshift_mutation wikiPageWikiLink Immunodeficiency.
- Frameshift_mutation wikiPageWikiLink Indel.
- Frameshift_mutation wikiPageWikiLink Insertion_(genetics).
- Frameshift_mutation wikiPageWikiLink Intron.
- Frameshift_mutation wikiPageWikiLink Large_intestine.
- Frameshift_mutation wikiPageWikiLink Lung.
- Frameshift_mutation wikiPageWikiLink Lungs.
- Frameshift_mutation wikiPageWikiLink MRNA.
- Frameshift_mutation wikiPageWikiLink Massive_parallel_sequencing.
- Frameshift_mutation wikiPageWikiLink Massively_parallel_sequencing.
- Frameshift_mutation wikiPageWikiLink Messenger_RNA.
- Frameshift_mutation wikiPageWikiLink Microsatellite.
- Frameshift_mutation wikiPageWikiLink Microsatellite_instability.
- Frameshift_mutation wikiPageWikiLink Mismatch_repair.
- Frameshift_mutation wikiPageWikiLink Missense_mutation.
- Frameshift_mutation wikiPageWikiLink Mitosis.
- Frameshift_mutation wikiPageWikiLink Mitotic.
- Frameshift_mutation wikiPageWikiLink Muscular_Dystrophy.
- Frameshift_mutation wikiPageWikiLink Muscular_dystrophy.
- Frameshift_mutation wikiPageWikiLink Mutation.
- Frameshift_mutation wikiPageWikiLink Neoplasm.
- Frameshift_mutation wikiPageWikiLink Nonsense_mutation.
- Frameshift_mutation wikiPageWikiLink Nucleotide.
- Frameshift_mutation wikiPageWikiLink Nucleotides.
- Frameshift_mutation wikiPageWikiLink Nylon-eating_bacteria.
- Frameshift_mutation wikiPageWikiLink Nylonase.
- Frameshift_mutation wikiPageWikiLink Open_reading_frame.
- Frameshift_mutation wikiPageWikiLink Organism.
- Frameshift_mutation wikiPageWikiLink Patent.
- Frameshift_mutation wikiPageWikiLink Peptide.
- Frameshift_mutation wikiPageWikiLink Phenotype.
- Frameshift_mutation wikiPageWikiLink Point_mutation.
- Frameshift_mutation wikiPageWikiLink Polypeptide.
- Frameshift_mutation wikiPageWikiLink Prokaryote.
- Frameshift_mutation wikiPageWikiLink Prokaryotes.
- Frameshift_mutation wikiPageWikiLink Proofreading.