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- Flagellar_motor_switch abstract "In molecular biology, the flagellar motor switch is a protein complex. In Escherichia coli and Salmonella typhimurium it regulates the direction of flagellar rotation and hence controls swimming behaviour. The switch is a complex apparatus that responds to signals transduced by the chemotaxis sensory signalling system during chemotactic behaviour. CheY, the chemotaxis response regulator, is believed to act directly on the switch to induce tumbles in the swimming pattern, but no physical interactions of CheY and switch proteins have yet been demonstrated.The switch complex comprises at least three proteins - FliG, FliM and FliN. It has been shown that FliG interacts with FliM, FliM interacts with itself, and FliM interacts with FliN. Several amino acids within the middle third of FliG appear to be strongly involved in the FliG-FliM interaction, with residues near the N- or C-termini being less important. Such clustering suggests that FliG-FliM interaction plays a central role in switching.Analysis of the FliG, FliM and FliN sequences shows that none are especially hydrophobic or appear to be integral membrane proteins. This result is consistent with other evidence suggesting that the proteins may be peripheral to the membrane, possibly mounted on the basal body M ring. FliG is present in about 25 copies per flagellum. The structure of the C-terminal domain of FliG is known, this domain functions specifically in motor rotation.".
- Flagellar_motor_switch symbol "FliG_C".
- Flagellar_motor_switch symbol "FliM".
- Flagellar_motor_switch thumbnail PDB_1lkv_EBI.jpg?width=300.
- Flagellar_motor_switch wikiPageID "32764387".
- Flagellar_motor_switch wikiPageLength "4399".
- Flagellar_motor_switch wikiPageOutDegree "22".
- Flagellar_motor_switch wikiPageRevisionID "591325919".
- Flagellar_motor_switch wikiPageWikiLink Amino_acid.
- Flagellar_motor_switch wikiPageWikiLink Amino_acids.
- Flagellar_motor_switch wikiPageWikiLink Basal_body.
- Flagellar_motor_switch wikiPageWikiLink Biomolecular_structure.
- Flagellar_motor_switch wikiPageWikiLink C-termini.
- Flagellar_motor_switch wikiPageWikiLink C-terminus.
- Flagellar_motor_switch wikiPageWikiLink Category:Protein_families.
- Flagellar_motor_switch wikiPageWikiLink Chemotaxis.
- Flagellar_motor_switch wikiPageWikiLink Escherichia_coli.
- Flagellar_motor_switch wikiPageWikiLink Flagella.
- Flagellar_motor_switch wikiPageWikiLink Flagellum.
- Flagellar_motor_switch wikiPageWikiLink Hydrophobe.
- Flagellar_motor_switch wikiPageWikiLink Hydrophobic.
- Flagellar_motor_switch wikiPageWikiLink Integral_membrane_protein.
- Flagellar_motor_switch wikiPageWikiLink Multiprotein_complex.
- Flagellar_motor_switch wikiPageWikiLink N-terminus.
- Flagellar_motor_switch wikiPageWikiLink Peripheral.
- Flagellar_motor_switch wikiPageWikiLink Protein.
- Flagellar_motor_switch wikiPageWikiLink Protein-protein_interaction.
- Flagellar_motor_switch wikiPageWikiLink Protein_complex.
- Flagellar_motor_switch wikiPageWikiLink Protein_domain.
- Flagellar_motor_switch wikiPageWikiLink Proteins.
- Flagellar_motor_switch wikiPageWikiLink Protein–protein_interaction.
- Flagellar_motor_switch wikiPageWikiLink Salmonella_enterica_subsp._enterica.
- Flagellar_motor_switch wikiPageWikiLink Salmonella_typhimurium.
- Flagellar_motor_switch wikiPageWikiLink Secondary_structure.
- Flagellar_motor_switch wikiPageWikiLink Sequence_(biology).
- Flagellar_motor_switch wikiPageWikiLink Signal_transduction.
- Flagellar_motor_switch wikiPageWikiLinkText "flagellar motor switch".
- Flagellar_motor_switch wikiPageWikiLinkText "flagellar switch-complex".
- Flagellar_motor_switch caption "crystal structure of the middle and c-terminal domains of the flagellar rotor protein flig".
- Flagellar_motor_switch hasPhotoCollection Flagellar_motor_switch.
- Flagellar_motor_switch interpro "IPR000090".
- Flagellar_motor_switch interpro "IPR001689".
- Flagellar_motor_switch name "Flagellar motor switch protein FliM".
- Flagellar_motor_switch name "FliG C-terminal domain".
- Flagellar_motor_switch pfam "PF01706".
- Flagellar_motor_switch pfam "PF02154".
- Flagellar_motor_switch pfamClan "CL0355".
- Flagellar_motor_switch pfamClan "CL0436".
- Flagellar_motor_switch scop "1".
- Flagellar_motor_switch symbol "FliG_C".
- Flagellar_motor_switch symbol "FliM".
- Flagellar_motor_switch wikiPageUsesTemplate Template:Infobox_protein_family.
- Flagellar_motor_switch wikiPageUsesTemplate Template:InterPro_content.
- Flagellar_motor_switch wikiPageUsesTemplate Template:Reflist.
- Flagellar_motor_switch subject Category:Protein_families.
- Flagellar_motor_switch type Biomolecule.
- Flagellar_motor_switch type Protein.
- Flagellar_motor_switch type Chemical.
- Flagellar_motor_switch type Thing.
- Flagellar_motor_switch type Q206229.
- Flagellar_motor_switch type Q8054.
- Flagellar_motor_switch comment "In molecular biology, the flagellar motor switch is a protein complex. In Escherichia coli and Salmonella typhimurium it regulates the direction of flagellar rotation and hence controls swimming behaviour. The switch is a complex apparatus that responds to signals transduced by the chemotaxis sensory signalling system during chemotactic behaviour.".
- Flagellar_motor_switch label "Flagellar motor switch".
- Flagellar_motor_switch sameAs m.0h3sx4v.
- Flagellar_motor_switch sameAs Q5456916.
- Flagellar_motor_switch sameAs Q5456916.
- Flagellar_motor_switch wasDerivedFrom Flagellar_motor_switch?oldid=591325919.
- Flagellar_motor_switch depiction PDB_1lkv_EBI.jpg.
- Flagellar_motor_switch isPrimaryTopicOf Flagellar_motor_switch.