Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Fibrinogen> ?p ?o }
- Fibrinogen abstract "Fibrinogen (factor I) is a glycoprotein in vertebrates that helps in the formation of blood clots. It consists of a linear array of three nodules held together by a very thin thread which is estimated to have a diameter between 8 and 15 Angstrom (Å). The two end nodules are alike but the center one is slightly smaller. Measurements of shadow lengths indicate that nodule diameters are in the range 50 to 70 Å. The length of the dried molecule is 475 ± 25 Å.The fibrinogen molecule is a soluble, large, and complex glycoprotein, 340 kDa plasma glycoprotein, that is converted by thrombin into fibrin during blood clot formation. It has a rod-like shape with dimensions of 9 × 47.5 × 6 nm and it shows a negative net charge at physiological pH (IP at pH 5.2). Fibrinogen is synthesized in the liver by the hepatocytes. The concentration of fibrinogen in the blood plasma is 200–400 mg/dL (normally measured using the Clauss method).During normal blood coagulation, a coagulation cascade activates the zymogen prothrombin by converting it into the serine protease thrombin. Thrombin then converts the soluble fibrinogen into insoluble fibrin strands. These strands are then cross-linked by factor XIII to form a blood clot. FXIIa stabilizes fibrin further by incorporation of the fibrinolysis inhibitors alpha-2-antiplasmin and TAFI (thrombin activatable fibrinolysis inhibitor, procarboxypeptidase B), and binding to several adhesive proteins of various cells. Both the activation of factor XIII by thrombin and plasminogen activator (t-PA) are catalyzed by fibrin. Fibrin specifically binds the activated coagulation factors factor Xa and thrombin and entraps them in the network of fibers, thus functioning as a temporary inhibitor of these enzymes, which stay active and can be released during fibrinolysis. Research from 2011 has shown that fibrin plays a key role in the inflammatory response and development of rheumatoid arthritis.".
- Fibrinogen arm "q".
- Fibrinogen band "28".
- Fibrinogen chromosome "4".
- Fibrinogen entrezgene "2243".
- Fibrinogen entrezgene "2244".
- Fibrinogen entrezgene "2266".
- Fibrinogen hgncid "3661".
- Fibrinogen hgncid "3662".
- Fibrinogen hgncid "3694".
- Fibrinogen omim "134820".
- Fibrinogen omim "134830".
- Fibrinogen omim "134850".
- Fibrinogen refseq "NM_000508".
- Fibrinogen refseq "NM_005141".
- Fibrinogen refseq "NM_021870".
- Fibrinogen symbol "FGA".
- Fibrinogen symbol "FGB".
- Fibrinogen symbol "FGG".
- Fibrinogen symbol "Fib_alpha".
- Fibrinogen symbol "Fibrinogen_C".
- Fibrinogen symbol "Fibrinogen_aC".
- Fibrinogen thumbnail Fibrinandligand.png?width=300.
- Fibrinogen uniprot "P02671".
- Fibrinogen uniprot "P02675".
- Fibrinogen uniprot "P02679".
- Fibrinogen wikiPageExternalLink Page1.htm.
- Fibrinogen wikiPageExternalLink link?SOURCE=Reactome&ID=REACT_214.
- Fibrinogen wikiPageExternalLink watch?v=RQpBj8ebbNY&index=3&list=WL.
- Fibrinogen wikiPageID "238687".
- Fibrinogen wikiPageLength "14950".
- Fibrinogen wikiPageOutDegree "73".
- Fibrinogen wikiPageRevisionID "678814427".
- Fibrinogen wikiPageWikiLink Acute-phase_protein.
- Fibrinogen wikiPageWikiLink Amino_acid.
- Fibrinogen wikiPageWikiLink Angiopoietin.
- Fibrinogen wikiPageWikiLink Angstrom.
- Fibrinogen wikiPageWikiLink Atomic_mass_unit.
- Fibrinogen wikiPageWikiLink Blood_plasma.
- Fibrinogen wikiPageWikiLink C-terminus.
- Fibrinogen wikiPageWikiLink Carbohydrate.
- Fibrinogen wikiPageWikiLink Carboxypeptidase_B2.
- Fibrinogen wikiPageWikiLink Cardiovascular_disease.
- Fibrinogen wikiPageWikiLink Category:Acute_phase_proteins.
- Fibrinogen wikiPageWikiLink Category:Blood_proteins.
- Fibrinogen wikiPageWikiLink Category:Coagulation_system.
- Fibrinogen wikiPageWikiLink Category:Precursor_proteins.
- Fibrinogen wikiPageWikiLink Clauss_method.
- Fibrinogen wikiPageWikiLink Coagulation.
- Fibrinogen wikiPageWikiLink Cryoprecipitate.
- Fibrinogen wikiPageWikiLink Cysteine.
- Fibrinogen wikiPageWikiLink Cytochalasin_D.
- Fibrinogen wikiPageWikiLink Disseminated_intravascular_coagulation.
- Fibrinogen wikiPageWikiLink Disulfide.
- Fibrinogen wikiPageWikiLink FGG.
- Fibrinogen wikiPageWikiLink Factor_X.
- Fibrinogen wikiPageWikiLink Factor_XIII.
- Fibrinogen wikiPageWikiLink Factor_Xa.
- Fibrinogen wikiPageWikiLink Fibrin.
- Fibrinogen wikiPageWikiLink Fibrinogen_alpha_chain.
- Fibrinogen wikiPageWikiLink Fibrinogen_beta_chain.
- Fibrinogen wikiPageWikiLink Fibrinolysis.
- Fibrinogen wikiPageWikiLink Fibrinopeptide.
- Fibrinogen wikiPageWikiLink Ficolin.
- Fibrinogen wikiPageWikiLink Fresh_frozen_plasma.
- Fibrinogen wikiPageWikiLink Gingiva.
- Fibrinogen wikiPageWikiLink Glycoprotein.
- Fibrinogen wikiPageWikiLink IIIa.
- Fibrinogen wikiPageWikiLink Hepatocyte.
- Fibrinogen wikiPageWikiLink Hexamer.
- Fibrinogen wikiPageWikiLink Inflammation.
- Fibrinogen wikiPageWikiLink KDa.
- Fibrinogen wikiPageWikiLink Lectin.
- Fibrinogen wikiPageWikiLink Liver.
- Fibrinogen wikiPageWikiLink Major_trauma.
- Fibrinogen wikiPageWikiLink Mammal.
- Fibrinogen wikiPageWikiLink N-terminus.
- Fibrinogen wikiPageWikiLink Oligomer.
- Fibrinogen wikiPageWikiLink Partial_thromboplastin_time.
- Fibrinogen wikiPageWikiLink Peptide.
- Fibrinogen wikiPageWikiLink Periodontal_disease.
- Fibrinogen wikiPageWikiLink Periodontal_pathology.
- Fibrinogen wikiPageWikiLink Physical_trauma.
- Fibrinogen wikiPageWikiLink Platelet.
- Fibrinogen wikiPageWikiLink Polymer.
- Fibrinogen wikiPageWikiLink Pregnancy.
- Fibrinogen wikiPageWikiLink Protein.
- Fibrinogen wikiPageWikiLink Prothrombin.
- Fibrinogen wikiPageWikiLink Prothrombin_time.
- Fibrinogen wikiPageWikiLink Rheumatoid_arthritis.
- Fibrinogen wikiPageWikiLink Sepsis.
- Fibrinogen wikiPageWikiLink Serine_protease.
- Fibrinogen wikiPageWikiLink T-PA.
- Fibrinogen wikiPageWikiLink TAFI.
- Fibrinogen wikiPageWikiLink Tachylectin_5A.
- Fibrinogen wikiPageWikiLink Thrombin.
- Fibrinogen wikiPageWikiLink Thrombus.
- Fibrinogen wikiPageWikiLink Tissue_plasminogen_activator.
- Fibrinogen wikiPageWikiLink Vein.
- Fibrinogen wikiPageWikiLink Vertebrate.