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- Fanapanel abstract "Fanapanel (INN, code name ZK-200775), also known as MPQX, is a quinoxalinedione derivative drug which acts as a competitive antagonist of the AMPA receptor. It was under development by Schering AG for the treatment of cerebral ischemia associated with stroke and trauma, but clinical trials were halted for safety reasons related to possible glial cell toxicity and due to intolerable side effects such as excessive sedation, reduction in consciousness (consisting of stupor and coma), and transient neurological deterioration. The drug was also observed to produce visual alteration and impairment, including blurred vision, strongly impaired color perception, and reduced visual acuity and dark vision, side effects thought to be caused by blockade of AMPA receptors in the retina.".
- Fanapanel atcPrefix "None".
- Fanapanel casNumber "161605-73-8".
- Fanapanel iupacName "{[7-(4-Morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydro-1(2H)-quinoxalinyl]methyl}phosphonic acid".
- Fanapanel pubchem "208953".
- Fanapanel thumbnail Fanapanel.svg?width=300.
- Fanapanel wikiPageID "44910077".
- Fanapanel wikiPageLength "4524".
- Fanapanel wikiPageOutDegree "32".
- Fanapanel wikiPageRevisionID "661025033".
- Fanapanel wikiPageWikiLink AMPA_receptor.
- Fanapanel wikiPageWikiLink Blurred_vision.
- Fanapanel wikiPageWikiLink Brain_ischemia.
- Fanapanel wikiPageWikiLink Category:AMPA_receptor_antagonists.
- Fanapanel wikiPageWikiLink Category:Ketones.
- Fanapanel wikiPageWikiLink Category:Morpholines.
- Fanapanel wikiPageWikiLink Category:Neuroprotective_agents.
- Fanapanel wikiPageWikiLink Category:Organofluorides.
- Fanapanel wikiPageWikiLink Category:Quinoxalines.
- Fanapanel wikiPageWikiLink Cerebral_ischemia.
- Fanapanel wikiPageWikiLink Chemical_derivative.
- Fanapanel wikiPageWikiLink Clinical_trial.
- Fanapanel wikiPageWikiLink Cognitive_deficit.
- Fanapanel wikiPageWikiLink Color_perception.
- Fanapanel wikiPageWikiLink Color_vision.
- Fanapanel wikiPageWikiLink Coma.
- Fanapanel wikiPageWikiLink Competitive_antagonist.
- Fanapanel wikiPageWikiLink Consciousness.
- Fanapanel wikiPageWikiLink Dark_vision.
- Fanapanel wikiPageWikiLink Derivative_(chemistry).
- Fanapanel wikiPageWikiLink Drug.
- Fanapanel wikiPageWikiLink Glial_cell_toxicity.
- Fanapanel wikiPageWikiLink International_Nonproprietary_Name.
- Fanapanel wikiPageWikiLink Irampanel.
- Fanapanel wikiPageWikiLink Neurological_deterioration.
- Fanapanel wikiPageWikiLink Neurotoxicity.
- Fanapanel wikiPageWikiLink Night_vision.
- Fanapanel wikiPageWikiLink Quinoxalinedione.
- Fanapanel wikiPageWikiLink Retina.
- Fanapanel wikiPageWikiLink Schering_AG.
- Fanapanel wikiPageWikiLink Sedation.
- Fanapanel wikiPageWikiLink Side_effect.
- Fanapanel wikiPageWikiLink Stroke.
- Fanapanel wikiPageWikiLink Stupor.
- Fanapanel wikiPageWikiLink Traumatic_brain_injury.
- Fanapanel wikiPageWikiLink Visual_acuity.
- Fanapanel wikiPageWikiLink Visual_impairment.
- Fanapanel wikiPageWikiLink Zonampanel.
- Fanapanel wikiPageWikiLinkText "Fanapanel".
- Fanapanel atcPrefix "None".
- Fanapanel c "14".
- Fanapanel casNumber "161605".
- Fanapanel chemspiderid "181046".
- Fanapanel f "3".
- Fanapanel h "15".
- Fanapanel hasPhotoCollection Fanapanel.
- Fanapanel inchi "1".
- Fanapanel inchikey "WZMQMKNCWDCCMT-UHFFFAOYAZ".
- Fanapanel iupacName "{[7--2,3-dioxo-6--3,4-dihydro-1-quinoxalinyl]methyl}phosphonic acid".
- Fanapanel molecularWeight "409.254".
- Fanapanel n "3".
- Fanapanel o "6".
- Fanapanel p "1".
- Fanapanel pubchem "208953".
- Fanapanel smiles "c1cCF".
- Fanapanel stdinchi "1".
- Fanapanel stdinchikey "WZMQMKNCWDCCMT-UHFFFAOYSA-N".
- Fanapanel wikiPageUsesTemplate Template:Drugbox.
- Fanapanel wikiPageUsesTemplate Template:Glutamatergics.
- Fanapanel wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Fanapanel wikiPageUsesTemplate Template:Reflist.
- Fanapanel subject Category:AMPA_receptor_antagonists.
- Fanapanel subject Category:Ketones.
- Fanapanel subject Category:Morpholines.
- Fanapanel subject Category:Neuroprotective_agents.
- Fanapanel subject Category:Organofluorides.
- Fanapanel subject Category:Quinoxalines.
- Fanapanel hypernym Drug.
- Fanapanel type ChemicalSubstance.
- Fanapanel type Drug.
- Fanapanel type ChemicalObject.
- Fanapanel type Thing.
- Fanapanel type Q8386.
- Fanapanel comment "Fanapanel (INN, code name ZK-200775), also known as MPQX, is a quinoxalinedione derivative drug which acts as a competitive antagonist of the AMPA receptor.".
- Fanapanel label "Fanapanel".
- Fanapanel sameAs m.012k_6hb.
- Fanapanel sameAs Q19597235.
- Fanapanel sameAs Q19597235.
- Fanapanel wasDerivedFrom Fanapanel?oldid=661025033.
- Fanapanel depiction Fanapanel.svg.
- Fanapanel isPrimaryTopicOf Fanapanel.