Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Fabomotizole> ?p ?o }
- Fabomotizole abstract "Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety.Experiments of mice have shown antimutagenic and antiteratogenic properties.Fabomotizole has found little clinical use outside of Russia and has not been evaluated by the FDA.".
- Fabomotizole atcPrefix "N05".
- Fabomotizole atcSuffix "BX04".
- Fabomotizole bioavailability "43.64".
- Fabomotizole casNumber "173352-39-1".
- Fabomotizole fdaUniiCode "HDO6HX6NZU".
- Fabomotizole iupacName "5-Ethoxy-2-[2-(morpholino)-ethylthio]benzimidazole".
- Fabomotizole pubchem "9862937".
- Fabomotizole thumbnail Fabomotizole.svg?width=300.
- Fabomotizole wikiPageID "25162841".
- Fabomotizole wikiPageLength "5874".
- Fabomotizole wikiPageOutDegree "23".
- Fabomotizole wikiPageRevisionID "680749415".
- Fabomotizole wikiPageWikiLink Anxiolytic.
- Fabomotizole wikiPageWikiLink BDNF.
- Fabomotizole wikiPageWikiLink Brain-derived_neurotrophic_factor.
- Fabomotizole wikiPageWikiLink Category:Anxiolytics.
- Fabomotizole wikiPageWikiLink Category:Benzimidazoles.
- Fabomotizole wikiPageWikiLink Category:Drugs_with_unknown_mechanisms_of_action.
- Fabomotizole wikiPageWikiLink Category:Melatonin_receptor_antagonists.
- Fabomotizole wikiPageWikiLink Category:Monoamine_oxidase_inhibitors.
- Fabomotizole wikiPageWikiLink Category:Morpholines.
- Fabomotizole wikiPageWikiLink Category:Phenol_ethers.
- Fabomotizole wikiPageWikiLink Category:Russian_drugs.
- Fabomotizole wikiPageWikiLink Category:Sigma_agonists.
- Fabomotizole wikiPageWikiLink Category:Thioethers.
- Fabomotizole wikiPageWikiLink Drug.
- Fabomotizole wikiPageWikiLink First-pass_effect.
- Fabomotizole wikiPageWikiLink First_pass_effect.
- Fabomotizole wikiPageWikiLink GABAergic.
- Fabomotizole wikiPageWikiLink Mechanism_of_action.
- Fabomotizole wikiPageWikiLink Melatonin_receptor_1A.
- Fabomotizole wikiPageWikiLink Melatonin_receptor_1C.
- Fabomotizole wikiPageWikiLink Muscle_relaxant.
- Fabomotizole wikiPageWikiLink Nerve_growth_factor.
- Fabomotizole wikiPageWikiLink Neuroprotection.
- Fabomotizole wikiPageWikiLink Neuroprotective.
- Fabomotizole wikiPageWikiLink Sedative.
- Fabomotizole wikiPageWikiLink Sigma_receptor.
- Fabomotizole wikiPageWikiLinkText "Fabomotizole".
- Fabomotizole atcPrefix "N05".
- Fabomotizole atcSuffix "BX04".
- Fabomotizole bioavailability "43.64".
- Fabomotizole c "15".
- Fabomotizole casNumber "173352".
- Fabomotizole chemspiderid "8038633".
- Fabomotizole eliminationHalfLife "194400.0".
- Fabomotizole h "21".
- Fabomotizole hasPhotoCollection Fabomotizole.
- Fabomotizole inchi "1".
- Fabomotizole inchikey "WWNUCVSRRUDYPP-UHFFFAOYAO".
- Fabomotizole iupacName "5".
- Fabomotizole legalUs "Not approved".
- Fabomotizole metabolism "extensive hepatic".
- Fabomotizole molecularWeight "307.41".
- Fabomotizole n "3".
- Fabomotizole o "2".
- Fabomotizole onset "468.00000000000006".
- Fabomotizole pubchem "9862937".
- Fabomotizole routesOfAdministration "Oral".
- Fabomotizole s "1".
- Fabomotizole smiles "C3COCCN3CCScnc1ccc2OCC".
- Fabomotizole stdinchi "1".
- Fabomotizole stdinchikey "WWNUCVSRRUDYPP-UHFFFAOYSA-N".
- Fabomotizole synonyms "Fabomotizole".
- Fabomotizole tradename "Afobazole".
- Fabomotizole unii "HDO6HX6NZU".
- Fabomotizole verifiedfields "changed".
- Fabomotizole verifiedrevid "477243457".
- Fabomotizole watchedfields "changed".
- Fabomotizole width "200".
- Fabomotizole wikiPageUsesTemplate Template:Anxiolytics.
- Fabomotizole wikiPageUsesTemplate Template:Drugbox.
- Fabomotizole wikiPageUsesTemplate Template:Melatonergics.
- Fabomotizole wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Fabomotizole wikiPageUsesTemplate Template:Reflist.
- Fabomotizole wikiPageUsesTemplate Template:Sigmaergics.
- Fabomotizole subject Category:Anxiolytics.
- Fabomotizole subject Category:Benzimidazoles.
- Fabomotizole subject Category:Drugs_with_unknown_mechanisms_of_action.
- Fabomotizole subject Category:Melatonin_receptor_antagonists.
- Fabomotizole subject Category:Monoamine_oxidase_inhibitors.
- Fabomotizole subject Category:Morpholines.
- Fabomotizole subject Category:Phenol_ethers.
- Fabomotizole subject Category:Russian_drugs.
- Fabomotizole subject Category:Sigma_agonists.
- Fabomotizole subject Category:Thioethers.
- Fabomotizole hypernym Drug.
- Fabomotizole type ChemicalSubstance.
- Fabomotizole type Drug.
- Fabomotizole type ChemicalObject.
- Fabomotizole type Thing.
- Fabomotizole type Q8386.
- Fabomotizole comment "Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms.".
- Fabomotizole label "Fabomotizole".
- Fabomotizole sameAs Fabomotizol.
- Fabomotizole sameAs آفوبازول.
- Fabomotizole sameAs Fabomotizole.
- Fabomotizole sameAs アホバゾール.
- Fabomotizole sameAs m.09gjt_3.