Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/FKBP> ?p ?o }
Showing triples 1 to 93 of
93
with 100 triples per page.
- FKBP abstract "FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence. FKBPs have been identified in many eukaryotes from yeast to humans and function as protein folding chaperones for proteins containing proline residues. Along with cyclophilin, FKBPs belong to the immunophilin family.FKBP12 is notable in humans for binding the immunosuppressant molecule tacrolimus (originally designated FK506), which is used in treating patients after organ transplant and patients suffering from autoimmune disorders. Tacrolimus has been found to reduce episodes of organ rejection over a related treatment, the drug ciclosporin, which binds cyclophilin. Both the FKBP-tacrolimus complex and the ciclosporin-cyclophilin complex inhibit a phosphatase called calcineurin, thus blocking signal transduction in the T-lymphocyte transduction pathway. This therapeutic role is not related to prolyl isomerase activity.".
- FKBP symbol "FKBP_C".
- FKBP thumbnail Fkbp-surface-1fkj.png?width=300.
- FKBP wikiPageExternalLink drugs.htm.
- FKBP wikiPageID "7130280".
- FKBP wikiPageLength "6069".
- FKBP wikiPageOutDegree "45".
- FKBP wikiPageRevisionID "682827535".
- FKBP wikiPageWikiLink AH_receptor-interacting_protein.
- FKBP wikiPageWikiLink AIPL1.
- FKBP wikiPageWikiLink Autoimmune.
- FKBP wikiPageWikiLink Autoimmunity.
- FKBP wikiPageWikiLink Biomolecular_structure.
- FKBP wikiPageWikiLink Calcineurin.
- FKBP wikiPageWikiLink Category:EC_5.2.1.
- FKBP wikiPageWikiLink Category:Protein_families.
- FKBP wikiPageWikiLink Chaperone_(protein).
- FKBP wikiPageWikiLink Chemically_induced_dimerization.
- FKBP wikiPageWikiLink Ciclosporin.
- FKBP wikiPageWikiLink Cyclophilin.
- FKBP wikiPageWikiLink Eukaryote.
- FKBP wikiPageWikiLink FK506.
- FKBP wikiPageWikiLink FKBP10.
- FKBP wikiPageWikiLink FKBP11.
- FKBP wikiPageWikiLink FKBP14.
- FKBP wikiPageWikiLink FKBP15.
- FKBP wikiPageWikiLink FKBP1A.
- FKBP wikiPageWikiLink FKBP1B.
- FKBP wikiPageWikiLink FKBP2.
- FKBP wikiPageWikiLink FKBP3.
- FKBP wikiPageWikiLink FKBP5.
- FKBP wikiPageWikiLink FKBP52.
- FKBP wikiPageWikiLink FKBP6.
- FKBP wikiPageWikiLink FKBP7.
- FKBP wikiPageWikiLink FKBP8.
- FKBP wikiPageWikiLink FKBP9.
- FKBP wikiPageWikiLink FKBP9L.
- FKBP wikiPageWikiLink Human.
- FKBP wikiPageWikiLink Immunophilin.
- FKBP wikiPageWikiLink Immunophilins.
- FKBP wikiPageWikiLink Immunosuppressant.
- FKBP wikiPageWikiLink Immunosuppression.
- FKBP wikiPageWikiLink LOC541473.
- FKBP wikiPageWikiLink Lymphocyte.
- FKBP wikiPageWikiLink Organ_transplant.
- FKBP wikiPageWikiLink Organ_transplantation.
- FKBP wikiPageWikiLink Phosphatase.
- FKBP wikiPageWikiLink Primary_structure.
- FKBP wikiPageWikiLink Proline.
- FKBP wikiPageWikiLink Prolyl_isomerase.
- FKBP wikiPageWikiLink Protein.
- FKBP wikiPageWikiLink Protein_folding.
- FKBP wikiPageWikiLink Signal_transduction.
- FKBP wikiPageWikiLink Tacrolimus.
- FKBP wikiPageWikiLink Yeast.
- FKBP wikiPageWikiLink File:Fkbp-cartoon-1fkj.png.
- FKBP wikiPageWikiLinkText "FK-binding protein 12".
- FKBP wikiPageWikiLinkText "FKBP".
- FKBP wikiPageWikiLinkText "FKBP12".
- FKBP caption "The human protein FKBP12 bound to FK506 . The protein surface is colored by hydrophobicity; the deep cleft in which the ligand is bound is hydrophobic.".
- FKBP hasPhotoCollection FKBP.
- FKBP interpro "IPR001179".
- FKBP name "FKBP-type peptidyl-prolyl cis-trans isomerase".
- FKBP pdb ", , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,".
- FKBP pfam "PF00254".
- FKBP prosite "PDOC00426".
- FKBP scop "1".
- FKBP symbol "FKBP_C".
- FKBP wikiPageUsesTemplate Template:Geometric_isomerases.
- FKBP wikiPageUsesTemplate Template:Isomerase-stub.
- FKBP wikiPageUsesTemplate Template:Pfam_box.
- FKBP wikiPageUsesTemplate Template:Reflist.
- FKBP subject Category:EC_5.2.1.
- FKBP subject Category:Protein_families.
- FKBP hypernym Family.
- FKBP type Article.
- FKBP type Biomolecule.
- FKBP type Protein.
- FKBP type Article.
- FKBP type Chemical.
- FKBP type Thing.
- FKBP type Q206229.
- FKBP type Q8054.
- FKBP comment "FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence. FKBPs have been identified in many eukaryotes from yeast to humans and function as protein folding chaperones for proteins containing proline residues.".
- FKBP label "FKBP".
- FKBP sameAs FKBP.
- FKBP sameAs FKBP.
- FKBP sameAs m.0h5rty.
- FKBP sameAs Q583864.
- FKBP sameAs Q583864.
- FKBP wasDerivedFrom FKBP?oldid=682827535.
- FKBP depiction Fkbp-surface-1fkj.png.
- FKBP isPrimaryTopicOf FKBP.