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- FERMT3 abstract "Fermitin family homolog 3) (FERMT3), also known as kindlin-3 (KIND3), MIG2-like protein (MIG2B), or unc-112-related protein 2 (URP2) is a protein that in humans is encoded by the FERMT3 gene.The kindlin family of proteins, member of the B4.1 superfamily, comprises three conserved protein homologues, kindlin 1, 2, and 3. They each contain a bipartite FERM domain comprising four subdomains F0, F1, F2, and F3 that show homology with the FERM head (H) domain of the cytoskeletal Talin protein. Kindlins have been linked to Kindler syndrome, leukocyte adhesion deficiency, cancer and other acquired human diseases. They are essential in the organisation of focal adhesions that mediate cell-extracellular matrix junctions and are involved in other cellular compartments that control cell-cell contacts and nucleus functioning. Therefore they are responsible for cell to cell crosstalk via cell-cell contacts and integrin mediated cell adhesion through focal adhesion proteins and as specialised adhesion structures of hematopoietic cells they are also present in podosome's F actin surrounding ring structure. Isoform 2 may act as a repressor of NF-kappa-B and apoptosis".
- FERMT3 entrezgene "83706".
- FERMT3 thumbnail FERMT-3_PROTEIN_SEQUENCE.png?width=300.
- FERMT3 wikiPageID "29949841".
- FERMT3 wikiPageLength "11930".
- FERMT3 wikiPageOutDegree "24".
- FERMT3 wikiPageRevisionID "635797254".
- FERMT3 wikiPageWikiLink Animal.
- FERMT3 wikiPageWikiLink Cytoskeleton.
- FERMT3 wikiPageWikiLink Erythrocyte.
- FERMT3 wikiPageWikiLink FERM_domain.
- FERMT3 wikiPageWikiLink Gene.
- FERMT3 wikiPageWikiLink Glanzmanns_thrombasthenia.
- FERMT3 wikiPageWikiLink Hemostasis.
- FERMT3 wikiPageWikiLink Kindler_syndrome.
- FERMT3 wikiPageWikiLink Leukocyte_adhesion_deficiency.
- FERMT3 wikiPageWikiLink Leukocytes.
- FERMT3 wikiPageWikiLink Metazoan.
- FERMT3 wikiPageWikiLink NF-kappa-B.
- FERMT3 wikiPageWikiLink NF-κB.
- FERMT3 wikiPageWikiLink Natural_Killer_cell.
- FERMT3 wikiPageWikiLink Natural_killer_cell.
- FERMT3 wikiPageWikiLink Neutrophil_granulocyte.
- FERMT3 wikiPageWikiLink Neutrophilia.
- FERMT3 wikiPageWikiLink Parazoa.
- FERMT3 wikiPageWikiLink Platelet.
- FERMT3 wikiPageWikiLink Platelets.
- FERMT3 wikiPageWikiLink Pleckstrin_homology_domain.
- FERMT3 wikiPageWikiLink Protein.
- FERMT3 wikiPageWikiLink Red_blood_cell.
- FERMT3 wikiPageWikiLink Talin_protein.
- FERMT3 wikiPageWikiLink Thrombosis.
- FERMT3 wikiPageWikiLink White_blood_cell.
- FERMT3 wikiPageWikiLink File:FERMT-3_PROTEIN_SEQUENCE.png.
- FERMT3 wikiPageWikiLink File:FERMT_3_Structure.jpg.
- FERMT3 wikiPageWikiLinkText "FERMT3".
- FERMT3 hasPhotoCollection FERMT3.
- FERMT3 wikiPageUsesTemplate Template:Citation_needed.
- FERMT3 wikiPageUsesTemplate Template:Cite_journal.
- FERMT3 wikiPageUsesTemplate Template:Gene-11-stub.
- FERMT3 wikiPageUsesTemplate Template:NLM_content.
- FERMT3 wikiPageUsesTemplate Template:PBB.
- FERMT3 wikiPageUsesTemplate Template:Primary_source-inline.
- FERMT3 wikiPageUsesTemplate Template:Refbegin.
- FERMT3 wikiPageUsesTemplate Template:Refend.
- FERMT3 wikiPageUsesTemplate Template:Reflist.
- FERMT3 hypernym Protein.
- FERMT3 type Article.
- FERMT3 type Biomolecule.
- FERMT3 type Protein.
- FERMT3 type Article.
- FERMT3 type Institute.
- FERMT3 type Source.
- FERMT3 type Thing.
- FERMT3 type Q206229.
- FERMT3 type Q8054.
- FERMT3 comment "Fermitin family homolog 3) (FERMT3), also known as kindlin-3 (KIND3), MIG2-like protein (MIG2B), or unc-112-related protein 2 (URP2) is a protein that in humans is encoded by the FERMT3 gene.The kindlin family of proteins, member of the B4.1 superfamily, comprises three conserved protein homologues, kindlin 1, 2, and 3. They each contain a bipartite FERM domain comprising four subdomains F0, F1, F2, and F3 that show homology with the FERM head (H) domain of the cytoskeletal Talin protein.".
- FERMT3 label "FERMT3".
- FERMT3 sameAs m.0fqs_7f.
- FERMT3 sameAs Q5425374.
- FERMT3 sameAs Q5425374.
- FERMT3 wasDerivedFrom FERMT3?oldid=635797254.
- FERMT3 depiction FERMT-3_PROTEIN_SEQUENCE.png.
- FERMT3 isPrimaryTopicOf FERMT3.