Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Erdosteine> ?p ?o }
Showing triples 1 to 93 of
93
with 100 triples per page.
- Erdosteine abstract "Erdosteine is a mucolytic. Specifically it is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains two blocked sulfhydryl groups which are released following first-pass metabolism. The three active metabolites exhibit mucolytic and free radical scavenging activity. Erdosteine modulates mucus production and viscosity and increases mucociliary transport, thereby improving expectoration. It also exhibits inhibitory activity against the effects of free radicals produced by cigarette smoke.Clinical studies in patients with chronic obstructive lung disease have demonstrated the efficacy and tolerability of erdosteine. Erdosteine 300 mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than bromhexine 30 mg twice daily.Co-administration of erdosteine and amoxicillin in patients with acute infective exacerbation of chronic bronchitis resulted in higher concentrations of the antibiotic in the sputum, leading to earlier and more pronounced amelioration of clinical symptoms compared with placebo.Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild. The LD50 is very high, 3,500-5,000 mg/kg.".
- Erdosteine atcPrefix "R05".
- Erdosteine atcSuffix "CB15".
- Erdosteine casNumber "84611-23-4".
- Erdosteine fdaUniiCode "76J0853EKA".
- Erdosteine iupacName "2-[(2-oxothiolan-3-yl)carbamoylmethylsulfanyl]acetic acid".
- Erdosteine pubchem "65632".
- Erdosteine thumbnail Erdosteine.png?width=300.
- Erdosteine wikiPageID "12285532".
- Erdosteine wikiPageLength "4114".
- Erdosteine wikiPageOutDegree "14".
- Erdosteine wikiPageRevisionID "682100694".
- Erdosteine wikiPageWikiLink Amoxicillin.
- Erdosteine wikiPageWikiLink Bromhexine.
- Erdosteine wikiPageWikiLink Category:Amides.
- Erdosteine wikiPageWikiLink Category:Antitussives.
- Erdosteine wikiPageWikiLink Category:Carboxylic_acids.
- Erdosteine wikiPageWikiLink Category:Thioethers.
- Erdosteine wikiPageWikiLink Category:Thiolactones.
- Erdosteine wikiPageWikiLink Chronic_bronchitis.
- Erdosteine wikiPageWikiLink Chronic_obstructive_pulmonary_disease.
- Erdosteine wikiPageWikiLink First_pass_effect.
- Erdosteine wikiPageWikiLink Median_lethal_dose.
- Erdosteine wikiPageWikiLink Mucokinetics.
- Erdosteine wikiPageWikiLink Mucolytic_agent.
- Erdosteine wikiPageWikiLink Radical_(chemistry).
- Erdosteine wikiPageWikiLink Thiol.
- Erdosteine wikiPageWikiLinkText "Erdosteine".
- Erdosteine wikiPageWikiLinkText "erdosteine".
- Erdosteine atcPrefix "R05".
- Erdosteine atcSuffix "CB15".
- Erdosteine c "8".
- Erdosteine casNumber "84611".
- Erdosteine chemspiderid "59073".
- Erdosteine eliminationHalfLife "-10800.0".
- Erdosteine h "11".
- Erdosteine hasPhotoCollection Erdosteine.
- Erdosteine inchi "1".
- Erdosteine inchikey "QGFORSXNKQLDNO-UHFFFAOYAW".
- Erdosteine iupacName "2".
- Erdosteine kegg "D07383".
- Erdosteine metabolism "hepatic".
- Erdosteine molecularWeight "249.309".
- Erdosteine n "1".
- Erdosteine o "4".
- Erdosteine proteinBound "65.0".
- Erdosteine pubchem "65632".
- Erdosteine routesOfAdministration "oral, inhalation".
- Erdosteine s "2".
- Erdosteine smiles "O=C1SCCC1NCCSCCO".
- Erdosteine stdinchi "1".
- Erdosteine stdinchikey "QGFORSXNKQLDNO-UHFFFAOYSA-N".
- Erdosteine unii "76".
- Erdosteine verifiedrevid "447814556".
- Erdosteine wikiPageUsesTemplate Template:Citation_needed.
- Erdosteine wikiPageUsesTemplate Template:Cough_and_cold_preparations.
- Erdosteine wikiPageUsesTemplate Template:Drugbox.
- Erdosteine wikiPageUsesTemplate Template:Reflist.
- Erdosteine wikiPageUsesTemplate Template:Respiratory-system-drug-stub.
- Erdosteine subject Category:Amides.
- Erdosteine subject Category:Antitussives.
- Erdosteine subject Category:Carboxylic_acids.
- Erdosteine subject Category:Thioethers.
- Erdosteine subject Category:Thiolactones.
- Erdosteine type Article.
- Erdosteine type ChemicalSubstance.
- Erdosteine type Drug.
- Erdosteine type Group.
- Erdosteine type Amide.
- Erdosteine type Article.
- Erdosteine type Chemical.
- Erdosteine type Drug.
- Erdosteine type Ether.
- Erdosteine type Group.
- Erdosteine type Heterocycle.
- Erdosteine type Thioester.
- Erdosteine type Thioether.
- Erdosteine type ChemicalObject.
- Erdosteine type Thing.
- Erdosteine type Q8386.
- Erdosteine comment "Erdosteine is a mucolytic. Specifically it is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains two blocked sulfhydryl groups which are released following first-pass metabolism. The three active metabolites exhibit mucolytic and free radical scavenging activity. Erdosteine modulates mucus production and viscosity and increases mucociliary transport, thereby improving expectoration.".
- Erdosteine label "Erdosteine".
- Erdosteine sameAs Erdosteina.
- Erdosteine sameAs Erdosteina.
- Erdosteine sameAs m.02vyztt.
- Erdosteine sameAs Erdostein.
- Erdosteine sameAs Erdostein.
- Erdosteine sameAs Ердостеїн.
- Erdosteine sameAs Q3731252.
- Erdosteine sameAs Q3731252.
- Erdosteine wasDerivedFrom Erdosteine?oldid=682100694.
- Erdosteine depiction Erdosteine.png.
- Erdosteine isPrimaryTopicOf Erdosteine.