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- Epigenetics_of_physical_exercise abstract "Epigenetics of physical exercise is the study of epigenetic modifications resulting from physical exercise to the genome of cells. Epigenetic modifications are heritable alterations that are not due to changes in the sequence of nucleotides. Epigenetic modifications, such as histone modifications and DNA methylation, alter the accessibility to DNA and change chromatin structure, thereby regulating patterns of gene expression. Methylated histones can act as binding sites for certain transcription factors due to their bromodomains and chromodomains. Methylated histones can also prevent the binding of transcription factors by hiding the transcription factor's recognition site, which is usually found on the major groove of DNA. The methyl groups bound to the cytosine residues lie in the major groove of DNA, the same region most transcription factors use to read a DNA sequence. A common epigenetic tag found in DNA is the covalent attachment of a methyl group to the C5 position of the cytosine found in CpG dinucleotide sequences. CpG methylation is an important mechanism of transcriptional silencing. Methylation of CpG islands is shown to reduce gene expression by the formation of tightly condensed heterochromatin that is transcriptionally inactive. CpG sites in a gene are most commonly found in the promoter regions of a gene while also being present in non promoter regions. The CpG sites in non promoter regions tend to be constitutively methylated, causing transcription machinery to ignore them as possible promoters. The CpG site near promoter regions are mostly left unmethylated until a cell decides to methylate them and repress transcription. Methylation of CpGs in promoter regions result in the transcriptional silencing of a gene. Environmental factors including physical exercise have been shown to have a beneficial influence on epigenetic modifications.".
- Epigenetics_of_physical_exercise wikiPageID "42663845".
- Epigenetics_of_physical_exercise wikiPageLength "16531".
- Epigenetics_of_physical_exercise wikiPageOutDegree "26".
- Epigenetics_of_physical_exercise wikiPageRevisionID "677446596".
- Epigenetics_of_physical_exercise wikiPageWikiLink Category:Epigenetics.
- Epigenetics_of_physical_exercise wikiPageWikiLink Category:Genetics.
- Epigenetics_of_physical_exercise wikiPageWikiLink Cellular_differentiation.
- Epigenetics_of_physical_exercise wikiPageWikiLink Chromatin.
- Epigenetics_of_physical_exercise wikiPageWikiLink Cytosine.
- Epigenetics_of_physical_exercise wikiPageWikiLink DNA_methylation.
- Epigenetics_of_physical_exercise wikiPageWikiLink Diabetes_mellitus_type_2.
- Epigenetics_of_physical_exercise wikiPageWikiLink Epigenetics.
- Epigenetics_of_physical_exercise wikiPageWikiLink GLUT4.
- Epigenetics_of_physical_exercise wikiPageWikiLink Gene_expression.
- Epigenetics_of_physical_exercise wikiPageWikiLink Gene_silencing.
- Epigenetics_of_physical_exercise wikiPageWikiLink Genome.
- Epigenetics_of_physical_exercise wikiPageWikiLink Glut4.
- Epigenetics_of_physical_exercise wikiPageWikiLink HDAC.
- Epigenetics_of_physical_exercise wikiPageWikiLink Heterochromatin.
- Epigenetics_of_physical_exercise wikiPageWikiLink Histone.
- Epigenetics_of_physical_exercise wikiPageWikiLink Histone_acetyltransferase.
- Epigenetics_of_physical_exercise wikiPageWikiLink Histone_deacetylase.
- Epigenetics_of_physical_exercise wikiPageWikiLink Methylation.
- Epigenetics_of_physical_exercise wikiPageWikiLink MicroRNA.
- Epigenetics_of_physical_exercise wikiPageWikiLink Micro_RNA.
- Epigenetics_of_physical_exercise wikiPageWikiLink Non-coding_RNA.
- Epigenetics_of_physical_exercise wikiPageWikiLink Nucleotide.
- Epigenetics_of_physical_exercise wikiPageWikiLink Osteoblast.
- Epigenetics_of_physical_exercise wikiPageWikiLink PGC-1a.
- Epigenetics_of_physical_exercise wikiPageWikiLink PPARGC1A.
- Epigenetics_of_physical_exercise wikiPageWikiLink PPARγ.
- Epigenetics_of_physical_exercise wikiPageWikiLink Peroxisome_proliferator-activated_receptor_gamma.
- Epigenetics_of_physical_exercise wikiPageWikiLink Promoter_(genetics).
- Epigenetics_of_physical_exercise wikiPageWikiLink Telomere.
- Epigenetics_of_physical_exercise wikiPageWikiLinkText "Epigenetics of physical exercise".
- Epigenetics_of_physical_exercise hasPhotoCollection Epigenetics_of_physical_exercise.
- Epigenetics_of_physical_exercise wikiPageUsesTemplate Template:Orphan.
- Epigenetics_of_physical_exercise wikiPageUsesTemplate Template:Reflist.
- Epigenetics_of_physical_exercise subject Category:Epigenetics.
- Epigenetics_of_physical_exercise subject Category:Genetics.
- Epigenetics_of_physical_exercise hypernym Study.
- Epigenetics_of_physical_exercise type Book.
- Epigenetics_of_physical_exercise comment "Epigenetics of physical exercise is the study of epigenetic modifications resulting from physical exercise to the genome of cells. Epigenetic modifications are heritable alterations that are not due to changes in the sequence of nucleotides. Epigenetic modifications, such as histone modifications and DNA methylation, alter the accessibility to DNA and change chromatin structure, thereby regulating patterns of gene expression.".
- Epigenetics_of_physical_exercise label "Epigenetics of physical exercise".
- Epigenetics_of_physical_exercise sameAs m.010hplkk.
- Epigenetics_of_physical_exercise sameAs Q18353747.
- Epigenetics_of_physical_exercise sameAs Q18353747.
- Epigenetics_of_physical_exercise wasDerivedFrom Epigenetics_of_physical_exercise?oldid=677446596.
- Epigenetics_of_physical_exercise isPrimaryTopicOf Epigenetics_of_physical_exercise.