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- Endophenotype abstract "Endophenotype is a genetic epidemiology term which is used to separate behavioral symptoms into more stable phenotypes with a clear genetic connection. The concept was coined by Bernard John and Kenneth R. Lewis in a 1966 paper attempting to explain the geographic distribution of grasshoppers. They claimed that the particular geographic distribution could not be explained by the obvious and external "exophenotype" of the grasshoppers, but instead must be explained by their microscopic and internal "endophenotype."The next major use of the term was in psychiatric genetics, to bridge the gap between high-level symptom presentation and low-level genetic variability, such as single nucleotide polymorphisms. It is therefore more applicable to more heritable disorders, such as bipolar disorder and schizophrenia. Since then, the concept has expanded to many other fields, such as the study of ADHD, addiction, Alzheimer's disease obesity and cystic fibrosis. Some other terms which have a similar meaning but do not stress the genetic connection as highly are "intermediate phenotype", "biological marker", "subclinical trait", "vulnerability marker", and "cognitive marker". The strength of an endophenotype is its ability to differentiate between potential diagnoses that present with similar symptoms.".
- Endophenotype wikiPageID "14102851".
- Endophenotype wikiPageLength "11783".
- Endophenotype wikiPageOutDegree "41".
- Endophenotype wikiPageRevisionID "679044453".
- Endophenotype wikiPageWikiLink 5-HT1B_receptor.
- Endophenotype wikiPageWikiLink ADHD.
- Endophenotype wikiPageWikiLink Addiction.
- Endophenotype wikiPageWikiLink Alzheimers_disease.
- Endophenotype wikiPageWikiLink Amygdala.
- Endophenotype wikiPageWikiLink Anterior_cingulate_cortex.
- Endophenotype wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- Endophenotype wikiPageWikiLink Biological_markers.
- Endophenotype wikiPageWikiLink Biomarker.
- Endophenotype wikiPageWikiLink Bipolar_disorder.
- Endophenotype wikiPageWikiLink CHRNA7.
- Endophenotype wikiPageWikiLink Category:Behavioural_genetics.
- Endophenotype wikiPageWikiLink Category:Bioindicators.
- Endophenotype wikiPageWikiLink Category:Biological_psychiatry.
- Endophenotype wikiPageWikiLink Category:Genetics.
- Endophenotype wikiPageWikiLink Cav1.2.
- Endophenotype wikiPageWikiLink Cystic_fibrosis.
- Endophenotype wikiPageWikiLink Diathesis–stress_model.
- Endophenotype wikiPageWikiLink FABP7.
- Endophenotype wikiPageWikiLink FMRI.
- Endophenotype wikiPageWikiLink Face_perception.
- Endophenotype wikiPageWikiLink Functional_magnetic_resonance_imaging.
- Endophenotype wikiPageWikiLink Genetic_epidemiology.
- Endophenotype wikiPageWikiLink Genetics.
- Endophenotype wikiPageWikiLink Grasshopper.
- Endophenotype wikiPageWikiLink Obesity.
- Endophenotype wikiPageWikiLink Phenotype.
- Endophenotype wikiPageWikiLink Phenotypes.
- Endophenotype wikiPageWikiLink Population_distribution.
- Endophenotype wikiPageWikiLink Prefrontal_cortex.
- Endophenotype wikiPageWikiLink Prepulse_inhibition.
- Endophenotype wikiPageWikiLink Psychiatric_genetics.
- Endophenotype wikiPageWikiLink Psychosis.
- Endophenotype wikiPageWikiLink Range_(biology).
- Endophenotype wikiPageWikiLink Reelin.
- Endophenotype wikiPageWikiLink Schizophrenia.
- Endophenotype wikiPageWikiLink Sensory_gating.
- Endophenotype wikiPageWikiLink Serotonin.
- Endophenotype wikiPageWikiLink Single-nucleotide_polymorphism.
- Endophenotype wikiPageWikiLink Single_nucleotide_polymorphism.
- Endophenotype wikiPageWikiLink Striatum.
- Endophenotype wikiPageWikiLink Suicide.
- Endophenotype wikiPageWikiLink Symptom.
- Endophenotype wikiPageWikiLink Voltage-dependent_calcium_channel.
- Endophenotype wikiPageWikiLink Working_memory.
- Endophenotype wikiPageWikiLinkText "Endophenotype".
- Endophenotype wikiPageWikiLinkText "Endophenotypic Factors".
- Endophenotype wikiPageWikiLinkText "Intermediate Phenotypes".
- Endophenotype wikiPageWikiLinkText "cognitive endophenotype".
- Endophenotype wikiPageWikiLinkText "endophenotype".
- Endophenotype wikiPageWikiLinkText "endophenotypes".
- Endophenotype wikiPageWikiLinkText "endophenotypic".
- Endophenotype hasPhotoCollection Endophenotype.
- Endophenotype wikiPageUsesTemplate Template:Cn.
- Endophenotype wikiPageUsesTemplate Template:Reflist.
- Endophenotype subject Category:Behavioural_genetics.
- Endophenotype subject Category:Bioindicators.
- Endophenotype subject Category:Biological_psychiatry.
- Endophenotype subject Category:Genetics.
- Endophenotype hypernym Term.
- Endophenotype type Article.
- Endophenotype type Model.
- Endophenotype type Article.
- Endophenotype type Model.
- Endophenotype comment "Endophenotype is a genetic epidemiology term which is used to separate behavioral symptoms into more stable phenotypes with a clear genetic connection. The concept was coined by Bernard John and Kenneth R. Lewis in a 1966 paper attempting to explain the geographic distribution of grasshoppers.".
- Endophenotype label "Endophenotype".
- Endophenotype sameAs Endofenotipo.
- Endophenotype sameAs m.03ctrbf.
- Endophenotype sameAs Эндофенотип.
- Endophenotype sameAs Endofenotyp.
- Endophenotype sameAs Q2032061.
- Endophenotype sameAs Q2032061.
- Endophenotype wasDerivedFrom Endophenotype?oldid=679044453.
- Endophenotype isPrimaryTopicOf Endophenotype.