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- Emicerfont abstract "Emicerfont (GW-876,008) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress, and activates the two corticotropin-releasing hormone receptors CRH-1 and CRH-2. This then triggers the release of corticotropin (ACTH), another hormone which is involved in the physiological response to stress. Emicerfont blocks the CRH-1 receptor, and so reduces ACTH release. It has been investigated for the treatment of irritable bowel syndrome and alcoholism, and while it was not effective enough to be adopted for medical use in these applications, it continues to be used for research, as the role of the CRH-ACTH system in IBS remains poorly understood.".
- Emicerfont atcPrefix "none".
- Emicerfont casNumber "786701-13-1".
- Emicerfont iupacName "1-(1-[1-(4-methoxy-2-methylphenyl)-6-methyl-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl)imidazolidin-2-one".
- Emicerfont pubchem "11223423".
- Emicerfont thumbnail Emicerfont_structure.png?width=300.
- Emicerfont wikiPageID "47504867".
- Emicerfont wikiPageLength "2932".
- Emicerfont wikiPageOutDegree "14".
- Emicerfont wikiPageRevisionID "675725532".
- Emicerfont wikiPageWikiLink Adrenocorticotropic_hormone.
- Emicerfont wikiPageWikiLink Alcoholism.
- Emicerfont wikiPageWikiLink Antalarmin.
- Emicerfont wikiPageWikiLink Category:CRF-1_antagonists.
- Emicerfont wikiPageWikiLink Category:Corticotropin-releasing_hormone.
- Emicerfont wikiPageWikiLink Chronic_stress.
- Emicerfont wikiPageWikiLink Corticotropin-releasing_hormone.
- Emicerfont wikiPageWikiLink Corticotropin-releasing_hormone_antagonist.
- Emicerfont wikiPageWikiLink Corticotropin-releasing_hormone_receptor.
- Emicerfont wikiPageWikiLink Corticotropin-releasing_hormone_receptor_1.
- Emicerfont wikiPageWikiLink Corticotropin_releasing_hormone.
- Emicerfont wikiPageWikiLink Corticotropin_releasing_hormone_antagonists.
- Emicerfont wikiPageWikiLink Corticotropin_releasing_hormone_receptor_1.
- Emicerfont wikiPageWikiLink GlaxoSmithKline.
- Emicerfont wikiPageWikiLink Irritable_bowel_syndrome.
- Emicerfont wikiPageWikiLink Pexacerfont.
- Emicerfont wikiPageWikiLink Verucerfont.
- Emicerfont wikiPageWikiLinkText "emicerfont".
- Emicerfont atcPrefix "none".
- Emicerfont c "22".
- Emicerfont casNumber "786701".
- Emicerfont h "24".
- Emicerfont hasPhotoCollection Emicerfont.
- Emicerfont iupacName "1".
- Emicerfont molecularWeight "404.465".
- Emicerfont n "6".
- Emicerfont o "2".
- Emicerfont pubchem "11223423".
- Emicerfont routesOfAdministration "Oral".
- Emicerfont smiles "CC1=CN2CCC3=C2N=CC".
- Emicerfont wikiPageUsesTemplate Template:Drugbox.
- Emicerfont wikiPageUsesTemplate Template:Neuropeptidergics.
- Emicerfont wikiPageUsesTemplate Template:Reflist.
- Emicerfont subject Category:CRF-1_antagonists.
- Emicerfont subject Category:Corticotropin-releasing_hormone.
- Emicerfont hypernym Drug.
- Emicerfont type ChemicalSubstance.
- Emicerfont type Drug.
- Emicerfont type ChemicalObject.
- Emicerfont type Thing.
- Emicerfont type Q8386.
- Emicerfont comment "Emicerfont (GW-876,008) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress, and activates the two corticotropin-releasing hormone receptors CRH-1 and CRH-2.".
- Emicerfont label "Emicerfont".
- Emicerfont wasDerivedFrom Emicerfont?oldid=675725532.
- Emicerfont depiction Emicerfont_structure.png.
- Emicerfont isPrimaryTopicOf Emicerfont.