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- Echinocandin_B abstract "Echinocandin B, a lipopeptide, is a naturally occurring cyclic hexapeptide with a linoleoyl side chain. It belongs to a class of antifungal agents called echinocandins, which inhibits the synthesis of glucan, a major component of the fungal cell wall, via noncompetitive inhibition of a crucial enzyme, β-(1,3)-D-glucan synthase. Echinocandin B is a fermentation product of Aspergillus nidulans and the closely related species, A. rugulosus; discovered in 1974 in A. nidulans var. echinulatus strain A 32204 in Germany, it was the first of the echinocandin class of antifungals. Echninocandin B can undergo deacylation (removal of the lipid side chain) by the action of a deacylase enzyme from the filamentous bacterium Actinoplanes utahensis, which catalyzes the cleavage of the linoleoyl side chain; in three subsequent synthetic steps, including a chemical reacylation, the antifungal drug anidulafungin is synthesized.".
- Echinocandin_B thumbnail Echinocandin_B.png?width=300.
- Echinocandin_B wikiPageID "17981572".
- Echinocandin_B wikiPageLength "4379".
- Echinocandin_B wikiPageOutDegree "12".
- Echinocandin_B wikiPageRevisionID "637931761".
- Echinocandin_B wikiPageWikiLink Anidulafungin.
- Echinocandin_B wikiPageWikiLink Aspergillus_nidulans.
- Echinocandin_B wikiPageWikiLink Category:Antifungals.
- Echinocandin_B wikiPageWikiLink Category:Echinocandins.
- Echinocandin_B wikiPageWikiLink Category:Peptides.
- Echinocandin_B wikiPageWikiLink Echinocandin.
- Echinocandin_B wikiPageWikiLink Enzyme.
- Echinocandin_B wikiPageWikiLink Fungicide.
- Echinocandin_B wikiPageWikiLink Linoleic_acid.
- Echinocandin_B wikiPageWikiLink Lipopeptide.
- Echinocandin_B wikiPageWikiLink Non-competitive_inhibition.
- Echinocandin_B wikiPageWikiLink Noncompetitive_inhibition.
- Echinocandin_B wikiPageWikiLinkText "Echinocandin B".
- Echinocandin_B wikiPageWikiLinkText "echinocandin B".
- Echinocandin_B hasPhotoCollection Echinocandin_B.
- Echinocandin_B imagefile "Echinocandin B.png".
- Echinocandin_B imagesize "250".
- Echinocandin_B verifiedfields "changed".
- Echinocandin_B verifiedrevid "428779394".
- Echinocandin_B watchedfields "changed".
- Echinocandin_B wikiPageUsesTemplate Template:Chembox.
- Echinocandin_B wikiPageUsesTemplate Template:Organic-compound-stub.
- Echinocandin_B subject Category:Antifungals.
- Echinocandin_B subject Category:Echinocandins.
- Echinocandin_B subject Category:Peptides.
- Echinocandin_B type Article.
- Echinocandin_B type Biomolecule.
- Echinocandin_B type ChemicalCompound.
- Echinocandin_B type ChemicalSubstance.
- Echinocandin_B type Article.
- Echinocandin_B type Biomolecule.
- Echinocandin_B type Peptide.
- Echinocandin_B type ChemicalObject.
- Echinocandin_B type Thing.
- Echinocandin_B type Q11173.
- Echinocandin_B comment "Echinocandin B, a lipopeptide, is a naturally occurring cyclic hexapeptide with a linoleoyl side chain. It belongs to a class of antifungal agents called echinocandins, which inhibits the synthesis of glucan, a major component of the fungal cell wall, via noncompetitive inhibition of a crucial enzyme, β-(1,3)-D-glucan synthase. Echinocandin B is a fermentation product of Aspergillus nidulans and the closely related species, A. rugulosus; discovered in 1974 in A. nidulans var.".
- Echinocandin_B label "Echinocandin B".
- Echinocandin_B sameAs اچینوکاندین_بی.
- Echinocandin_B sameAs m.047m8j3.
- Echinocandin_B sameAs Ehinokandin_B.
- Echinocandin_B sameAs Ehinokandin_B.
- Echinocandin_B sameAs Q5332458.
- Echinocandin_B sameAs Q5332458.
- Echinocandin_B wasDerivedFrom Echinocandin_B?oldid=637931761.
- Echinocandin_B depiction Echinocandin_B.png.
- Echinocandin_B isPrimaryTopicOf Echinocandin_B.