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- Dual-specificity_phosphatase abstract "Dual-specificity phosphatase is a form of phosphatase that can act upon tyrosine or serine/threonine residues.There are several families of Dual-Specificity Phosphatase (DUSP) enzymes in mammals. All share a similar catalytic mechanism, by which a conserved cysteine residue forms a covalent intermediate with the phosphate group to be eliminated. The residues surrounding their calatytic core obey a rather strict consensus: His-Cys-x-x-x-x-x-Arg-Ser. The serine side chain and an additional conserved aspartate play a central role in the elimination of the Cys-linked intermediate, thus completing their enzymatic cycle. The main difference between tyrosine-specific phosphatases and dual-specificity phosphatases lies in the width of the latter enzymes' catalytic pocket: thus they can accommodate phosphorylated serine or threonine side chains as well as phosphorylated tyrosines.".
- Dual-specificity_phosphatase wikiPageID "30010105".
- Dual-specificity_phosphatase wikiPageLength "3927".
- Dual-specificity_phosphatase wikiPageOutDegree "5".
- Dual-specificity_phosphatase wikiPageRevisionID "607903765".
- Dual-specificity_phosphatase wikiPageWikiLink Category:Enzymes.
- Dual-specificity_phosphatase wikiPageWikiLink Phosphatase.
- Dual-specificity_phosphatase wikiPageWikiLink Serine.
- Dual-specificity_phosphatase wikiPageWikiLink Threonine.
- Dual-specificity_phosphatase wikiPageWikiLink Tyrosine.
- Dual-specificity_phosphatase wikiPageWikiLinkText "".
- Dual-specificity_phosphatase wikiPageWikiLinkText "Dual-specificity phosphatase".
- Dual-specificity_phosphatase wikiPageWikiLinkText "dual-specificity phosphatase".
- Dual-specificity_phosphatase hasPhotoCollection Dual-specificity_phosphatase.
- Dual-specificity_phosphatase wikiPageUsesTemplate Template:Biochem-stub.
- Dual-specificity_phosphatase wikiPageUsesTemplate Template:Intracellular_signaling_peptides_and_proteins.
- Dual-specificity_phosphatase wikiPageUsesTemplate Template:Protein_tyrosine_phosphatases.
- Dual-specificity_phosphatase wikiPageUsesTemplate Template:Reflist.
- Dual-specificity_phosphatase subject Category:Enzymes.
- Dual-specificity_phosphatase hypernym Form.
- Dual-specificity_phosphatase comment "Dual-specificity phosphatase is a form of phosphatase that can act upon tyrosine or serine/threonine residues.There are several families of Dual-Specificity Phosphatase (DUSP) enzymes in mammals. All share a similar catalytic mechanism, by which a conserved cysteine residue forms a covalent intermediate with the phosphate group to be eliminated. The residues surrounding their calatytic core obey a rather strict consensus: His-Cys-x-x-x-x-x-Arg-Ser.".
- Dual-specificity_phosphatase label "Dual-specificity phosphatase".
- Dual-specificity_phosphatase sameAs m.0g54q3k.
- Dual-specificity_phosphatase sameAs Q5310143.
- Dual-specificity_phosphatase sameAs Q5310143.
- Dual-specificity_phosphatase wasDerivedFrom Dual-specificity_phosphatase?oldid=607903765.
- Dual-specificity_phosphatase isPrimaryTopicOf Dual-specificity_phosphatase.