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- DnaB_helicase abstract "DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerisation of the N-terminal domain has been observed and may occur during the enzymatic cycle. Initially when DnaB binds to dnaA, it is associated with dnaC, a negative regulator. After DnaC dissociates, DnaB binds dnaG.The N-terminal has a multi-helical structure that forms an orthogonal bundle. The C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.In eukaryotes, helicase function is provided by the MCM (Minichromosome maintenance) complex.The DnaB helicase is the product of the dnaB gene. The helicase enzyme that is produced is a hexamer in E. coli, as well as in many other bacteria.The energy for DnaB activity is provided by NTP hydrolysis. Mechanical energy moves the DnaB into the replication fork, physically splitting it in half.".
- DnaB_helicase ecNumber "3.6.1.-".
- DnaB_helicase entrezgene "948555".
- DnaB_helicase symbol "DnaB".
- DnaB_helicase symbol "DnaB_C".
- DnaB_helicase symbol "dnaB".
- DnaB_helicase thumbnail PDB_1jwe_EBI.jpg?width=300.
- DnaB_helicase uniprot "P0ACB0".
- DnaB_helicase wikiPageID "505434".
- DnaB_helicase wikiPageLength "5652".
- DnaB_helicase wikiPageOutDegree "18".
- DnaB_helicase wikiPageRevisionID "682229598".
- DnaB_helicase wikiPageWikiLink ATP_hydrolysis.
- DnaB_helicase wikiPageWikiLink Adenosine_triphosphate.
- DnaB_helicase wikiPageWikiLink Bacteria.
- DnaB_helicase wikiPageWikiLink Category:DNA_replication.
- DnaB_helicase wikiPageWikiLink Category:EC_3.6.1.
- DnaB_helicase wikiPageWikiLink Category:Protein_domains.
- DnaB_helicase wikiPageWikiLink DNA.
- DnaB_helicase wikiPageWikiLink DNA_replication.
- DnaB_helicase wikiPageWikiLink DnaA.
- DnaB_helicase wikiPageWikiLink DnaC.
- DnaB_helicase wikiPageWikiLink DnaG.
- DnaB_helicase wikiPageWikiLink Enzyme.
- DnaB_helicase wikiPageWikiLink Minichromosome_maintenance.
- DnaB_helicase wikiPageWikiLink N-terminal.
- DnaB_helicase wikiPageWikiLink N-terminus.
- DnaB_helicase wikiPageWikiLink Protein.
- DnaB_helicase wikiPageWikiLink Protein_dimer.
- DnaB_helicase wikiPageWikiLink Protein_domain.
- DnaB_helicase wikiPageWikiLink Replication_fork.
- DnaB_helicase wikiPageWikiLinkText "DnaB helicase".
- DnaB_helicase wikiPageWikiLinkText "DnaB".
- DnaB_helicase wikiPageWikiLinkText "dnaB helicase".
- DnaB_helicase wikiPageWikiLinkText "dnaB".
- DnaB_helicase caption "nmr structure of the n-terminal domain of e. coli dnab helicase".
- DnaB_helicase cdd "cd00984".
- DnaB_helicase ecnumber "3.6".
- DnaB_helicase entrezgene "948555".
- DnaB_helicase hasPhotoCollection DnaB_helicase.
- DnaB_helicase interpro "IPR007693".
- DnaB_helicase interpro "IPR007694".
- DnaB_helicase name "DnaB-like helicase C terminal domain".
- DnaB_helicase name "DnaB-like helicase N terminal domain".
- DnaB_helicase name "Replicative DNA helicase".
- DnaB_helicase pfam "PF00772".
- DnaB_helicase pfam "PF03796".
- DnaB_helicase pfamClan "CL0023".
- DnaB_helicase scop "1".
- DnaB_helicase symbol "DnaB".
- DnaB_helicase symbol "DnaB_C".
- DnaB_helicase symbol "dnaB".
- DnaB_helicase uniprot "P0ACB0".
- DnaB_helicase wikiPageUsesTemplate Template:Citation_needed.
- DnaB_helicase wikiPageUsesTemplate Template:Cleanup.
- DnaB_helicase wikiPageUsesTemplate Template:DNA_replication.
- DnaB_helicase wikiPageUsesTemplate Template:Infobox_protein.
- DnaB_helicase wikiPageUsesTemplate Template:Infobox_protein_family.
- DnaB_helicase wikiPageUsesTemplate Template:InterPro_content.
- DnaB_helicase wikiPageUsesTemplate Template:Lowercase_title.
- DnaB_helicase wikiPageUsesTemplate Template:MeshName.
- DnaB_helicase wikiPageUsesTemplate Template:Reflist.
- DnaB_helicase subject Category:DNA_replication.
- DnaB_helicase subject Category:EC_3.6.1.
- DnaB_helicase subject Category:Protein_domains.
- DnaB_helicase hypernym Enzyme.
- DnaB_helicase type Article.
- DnaB_helicase type Biomolecule.
- DnaB_helicase type Protein.
- DnaB_helicase type Article.
- DnaB_helicase type Chemical.
- DnaB_helicase type Domain.
- DnaB_helicase type Page.
- DnaB_helicase type Thing.
- DnaB_helicase type Q206229.
- DnaB_helicase type Q8054.
- DnaB_helicase comment "DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerisation of the N-terminal domain has been observed and may occur during the enzymatic cycle. Initially when DnaB binds to dnaA, it is associated with dnaC, a negative regulator.".
- DnaB_helicase label "DnaB helicase".
- DnaB_helicase sameAs هيليكاز_دانا_بي.
- DnaB_helicase sameAs DnaBヘリカーゼ.
- DnaB_helicase sameAs m.02jhgw.
- DnaB_helicase sameAs DnaB.
- DnaB_helicase sameAs DnaB_helikaza.
- DnaB_helicase sameAs DnaB_helikaza.
- DnaB_helicase sameAs Q2033993.
- DnaB_helicase sameAs Q2033993.
- DnaB_helicase wasDerivedFrom DnaB_helicase?oldid=682229598.
- DnaB_helicase depiction PDB_1jwe_EBI.jpg.
- DnaB_helicase isPrimaryTopicOf DnaB_helicase.
- DnaB_helicase name "Replicative DNA helicase".