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- Demecolcine abstract "Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed.During cell division Demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically Demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.In animal cloning procedures Demecolcine makes an ovum eject its nucleus, creating space for insertion of a new nucleus.".
- Demecolcine atcPrefix "L01".
- Demecolcine atcSuffix "CC01".
- Demecolcine casNumber "477-30-5".
- Demecolcine fdaUniiCode "Z01IVE25KI".
- Demecolcine iupacName "(S)-1,2,3,10-Tetramethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one".
- Demecolcine pubchem "2832".
- Demecolcine thumbnail Demecolcine.png?width=300.
- Demecolcine wikiPageID "20362448".
- Demecolcine wikiPageLength "4461".
- Demecolcine wikiPageOutDegree "19".
- Demecolcine wikiPageRevisionID "668907423".
- Demecolcine wikiPageWikiLink Acetyl.
- Demecolcine wikiPageWikiLink Alkaloid.
- Demecolcine wikiPageWikiLink Amine.
- Demecolcine wikiPageWikiLink Amino.
- Demecolcine wikiPageWikiLink Category:Alkaloids.
- Demecolcine wikiPageWikiLink Category:Heptalenes.
- Demecolcine wikiPageWikiLink Category:Ketones.
- Demecolcine wikiPageWikiLink Category:Microtubule_inhibitors.
- Demecolcine wikiPageWikiLink Category:Phenol_ethers.
- Demecolcine wikiPageWikiLink Cell_(biology).
- Demecolcine wikiPageWikiLink Chemotherapy.
- Demecolcine wikiPageWikiLink Colchicine.
- Demecolcine wikiPageWikiLink Depolymerization.
- Demecolcine wikiPageWikiLink Karyotype.
- Demecolcine wikiPageWikiLink Karyotyping.
- Demecolcine wikiPageWikiLink Metaphase.
- Demecolcine wikiPageWikiLink Methyl.
- Demecolcine wikiPageWikiLink Methyl_group.
- Demecolcine wikiPageWikiLink Microtubule.
- Demecolcine wikiPageWikiLink Microtubules.
- Demecolcine wikiPageWikiLink Spindle_fibre.
- Demecolcine wikiPageWikiLink Vinblastine.
- Demecolcine wikiPageWikiLinkText "Demecolcine".
- Demecolcine wikiPageWikiLinkText "demecolcine".
- Demecolcine alt "Ball-and-stick model of the demecolcine molecule".
- Demecolcine alt "Skeletal formula of demecolcine".
- Demecolcine atcPrefix "L01".
- Demecolcine atcSuffix "CC01".
- Demecolcine c "21".
- Demecolcine casNumber "477".
- Demecolcine chembl "312862".
- Demecolcine chemspiderid "191135".
- Demecolcine h "25".
- Demecolcine hasPhotoCollection Demecolcine.
- Demecolcine image "Demecolcine 3D ball.png".
- Demecolcine inchi "1".
- Demecolcine inchikey "NNJPGOLRFBJNIW-HNNXBMFYBY".
- Demecolcine iupacName "-12310".
- Demecolcine molecularWeight "371.43".
- Demecolcine n "1".
- Demecolcine o "5".
- Demecolcine pubchem "2832".
- Demecolcine smiles "O=C/1C=C/C=C2\C[C@@H]CCc3c2cccc3".
- Demecolcine stdinchi "1".
- Demecolcine stdinchikey "NNJPGOLRFBJNIW-HNNXBMFYSA-N".
- Demecolcine unii "Z01IVE25KI".
- Demecolcine verifiedrevid "414414817".
- Demecolcine watchedfields "changed".
- Demecolcine wikiPageUsesTemplate Template:Antineoplastic-drug-stub.
- Demecolcine wikiPageUsesTemplate Template:Chemotherapeutic_agents.
- Demecolcine wikiPageUsesTemplate Template:Drugbox.
- Demecolcine wikiPageUsesTemplate Template:Reflist.
- Demecolcine subject Category:Alkaloids.
- Demecolcine subject Category:Heptalenes.
- Demecolcine subject Category:Ketones.
- Demecolcine subject Category:Microtubule_inhibitors.
- Demecolcine subject Category:Phenol_ethers.
- Demecolcine hypernym Drug.
- Demecolcine type Biomolecule.
- Demecolcine type ChemicalSubstance.
- Demecolcine type Drug.
- Demecolcine type Group.
- Demecolcine type Alkaloid.
- Demecolcine type Biomolecule.
- Demecolcine type Chemical.
- Demecolcine type Ether.
- Demecolcine type Group.
- Demecolcine type Inhibitor.
- Demecolcine type Ketone.
- Demecolcine type Toxin.
- Demecolcine type ChemicalObject.
- Demecolcine type Thing.
- Demecolcine type Q8386.
- Demecolcine comment "Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic.".
- Demecolcine label "Demecolcine".
- Demecolcine sameAs m.04zwrkt.
- Demecolcine sameAs Demekolcin.
- Demecolcine sameAs Q16959658.
- Demecolcine sameAs Q16959658.
- Demecolcine wasDerivedFrom Demecolcine?oldid=668907423.
- Demecolcine depiction Demecolcine.png.
- Demecolcine isPrimaryTopicOf Demecolcine.