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- David_MacLennan abstract "For the Scottish theatre practitioner, see David MacLennan (theatre practitioner).For the CEO of Cargill, see Dave MacLennan.David H MacLennan, OC, OOnt, FRSC, FRS (born July 3, 1937) is a Canadian biochemist and geneticist known for his basic work on proteins that regulate calcium flux through the sarcoplasmic reticulum (SR), thereby regulating muscle contraction and relaxation, and for his discoveries in the field of muscle diseases caused by genetic defects in calcium regulatory proteins.Born in Swan River Manitoba, he received a BSA from the University of Manitoba in 1959 and a DSc (hc) in 2001. He received MS (1961) and PhD (1963) degrees from Purdue University and was then a Postdoctoral Fellow (1963-1964) and an Assistant Professor (1964-1968) at the University of Wisconsin. In 1969, he was appointed Associate Professor in the Banting and Best Department of Medical Research and, later, Professor (1974), Chair (1978-1990), J. W. Billes Professor of Medical Research (1987-) and University Professor (1993-).MacLennan has made fundamental contributions to our understanding of the mechanism of ion transport by SR calcium pumps, the storage of calcium in the SR by acidic lumenal proteins and the release of calcium from the SR by calcium release channels. He has led teams that defined the genetic basis for the human skeletal muscle diseases, malignant hyperthermia, central core disease and Brody disease and he has demonstrated that mutations in phospholamban, a regulator of the calcium pump, can cause cardiomyopathy. His identification of a calcium release channel mutation that causes porcine stress syndrome resulted in a diagnostic test that has decreased the incidence of the disease dramatically, with substantial economic benefits to the swine industry.".
- David_MacLennan birthDate "1937-07-03".
- David_MacLennan birthYear "1937".
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- David_MacLennan wikiPageWikiLink Canadian_Medical_Hall_of_Fame.
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- David_MacLennan wikiPageWikiLink Dave_MacLennan.
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- David_MacLennan wikiPageWikiLink Gairdner_Foundation_International_Award.
- David_MacLennan wikiPageWikiLink International_Society_for_Heart_Research.
- David_MacLennan wikiPageWikiLink Izaak-Walton-Killam_Award.
- David_MacLennan wikiPageWikiLink Killam_Prize.
- David_MacLennan wikiPageWikiLink Malignant_hyperthermia.
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- David_MacLennan wikiPageWikiLink Phospholamban.
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- David_MacLennan wikiPageWikiLink Royal_Society_of_Canada.
- David_MacLennan wikiPageWikiLink Royal_Society_of_London.
- David_MacLennan wikiPageWikiLink Skeletal_muscle.
- David_MacLennan wikiPageWikiLink University_of_Manitoba.
- David_MacLennan wikiPageWikiLinkText "David MacLennan".
- David_MacLennan dateOfBirth "1937-07-03".
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- David_MacLennan name "Maclennan, David".
- David_MacLennan shortDescription "Canadian medical researcher".
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- David_MacLennan description "Canadian medical researcher".
- David_MacLennan description "Canadian medical researcher".
- David_MacLennan subject Category:1937_births.
- David_MacLennan subject Category:Canadian_Medical_Hall_of_Fame.
- David_MacLennan subject Category:Canadian_medical_researchers.
- David_MacLennan subject Category:Fellows_of_the_Royal_Society.
- David_MacLennan subject Category:Fellows_of_the_Royal_Society_of_Canada.
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- David_MacLennan subject Category:Members_of_the_United_States_National_Academy_of_Sciences.
- David_MacLennan subject Category:Officers_of_the_Order_of_Canada.
- David_MacLennan subject Category:University_of_Toronto_faculty.
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- David_MacLennan comment "For the Scottish theatre practitioner, see David MacLennan (theatre practitioner).For the CEO of Cargill, see Dave MacLennan.David H MacLennan, OC, OOnt, FRSC, FRS (born July 3, 1937) is a Canadian biochemist and geneticist known for his basic work on proteins that regulate calcium flux through the sarcoplasmic reticulum (SR), thereby regulating muscle contraction and relaxation, and for his discoveries in the field of muscle diseases caused by genetic defects in calcium regulatory proteins.Born in Swan River Manitoba, he received a BSA from the University of Manitoba in 1959 and a DSc (hc) in 2001. ".
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- David_MacLennan sameAs 戴维·麦克伦南.
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- David_MacLennan depiction Photo,_Dr_David_H_MacLennan.jpeg.
- David_MacLennan givenName "David".
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- David_MacLennan name "David Maclennan".
- David_MacLennan name "Maclennan, David".
- David_MacLennan surname "Maclennan".