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- DNA_polymerase_alpha abstract "DNA polymerase alpha also known as Pol α is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase alpha complex consists of 4 subunits: POLA1, POLA2, PRIM1, and PRIM2.Pol α has limited processivity and lacks 3′ exonuclease activity for proofreading errors. Thus it is not well suited to efficiently and accurately copy long templates (unlike Pol Delta and Epsilon). Instead it plays a more limited role in replication. Pol α is responsible for the initiation of DNA replication at origins of replication (on both the leading and lagging strands) and during synthesis of Okazaki fragments on the lagging strand. The Pol α complex (pol α-DNA primase complex) consists of four subunits: the catalytic subunit POLA1, the regulatory subunit POLA2, and the small and the large primase subunits PRIM1 and PRIM2 respectively. Once primase has created the RNA primer, Pol α starts replication elongating the primer with ~20 nucleotides.".
- DNA_polymerase_alpha ecNumber "2.7.7.7".
- DNA_polymerase_alpha wikiPageID "44593240".
- DNA_polymerase_alpha wikiPageLength "1686".
- DNA_polymerase_alpha wikiPageOutDegree "12".
- DNA_polymerase_alpha wikiPageRevisionID "638317832".
- DNA_polymerase_alpha wikiPageWikiLink Category:EC_2.7.7.
- DNA_polymerase_alpha wikiPageWikiLink DNA_polymerase_alpha_catalytic_subunit.
- DNA_polymerase_alpha wikiPageWikiLink DNA_polymerase_alpha_subunit_2.
- DNA_polymerase_alpha wikiPageWikiLink DNA_replication.
- DNA_polymerase_alpha wikiPageWikiLink Enzyme.
- DNA_polymerase_alpha wikiPageWikiLink Eukaryote.
- DNA_polymerase_alpha wikiPageWikiLink Exonuclease.
- DNA_polymerase_alpha wikiPageWikiLink Okazaki_fragment.
- DNA_polymerase_alpha wikiPageWikiLink Okazaki_fragments.
- DNA_polymerase_alpha wikiPageWikiLink POLA1.
- DNA_polymerase_alpha wikiPageWikiLink POLA2.
- DNA_polymerase_alpha wikiPageWikiLink PRIM1.
- DNA_polymerase_alpha wikiPageWikiLink PRIM2.
- DNA_polymerase_alpha wikiPageWikiLink Processivity.
- DNA_polymerase_alpha wikiPageWikiLinkText "DNA polymerase alpha".
- DNA_polymerase_alpha wikiPageWikiLinkText "Pol α (alpha)".
- DNA_polymerase_alpha wikiPageWikiLinkText "Pol α".
- DNA_polymerase_alpha casNumber "9012".
- DNA_polymerase_alpha ecNumber "2.7".
- DNA_polymerase_alpha hasPhotoCollection DNA_polymerase_alpha.
- DNA_polymerase_alpha iubmbEcNumber "2".
- DNA_polymerase_alpha name "DNA-directed DNA polymerase".
- DNA_polymerase_alpha wikiPageUsesTemplate Template:DNA_replication.
- DNA_polymerase_alpha wikiPageUsesTemplate Template:Enzyme-stub.
- DNA_polymerase_alpha wikiPageUsesTemplate Template:Infobox_enzyme.
- DNA_polymerase_alpha wikiPageUsesTemplate Template:MeshName.
- DNA_polymerase_alpha wikiPageUsesTemplate Template:NLM_content.
- DNA_polymerase_alpha wikiPageUsesTemplate Template:Reflist.
- DNA_polymerase_alpha subject Category:EC_2.7.7.
- DNA_polymerase_alpha hypernym Complex.
- DNA_polymerase_alpha type Biomolecule.
- DNA_polymerase_alpha type Building.
- DNA_polymerase_alpha type Enzyme.
- DNA_polymerase_alpha type Thing.
- DNA_polymerase_alpha type Q206229.
- DNA_polymerase_alpha type Q8047.
- DNA_polymerase_alpha comment "DNA polymerase alpha also known as Pol α is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase alpha complex consists of 4 subunits: POLA1, POLA2, PRIM1, and PRIM2.Pol α has limited processivity and lacks 3′ exonuclease activity for proofreading errors. Thus it is not well suited to efficiently and accurately copy long templates (unlike Pol Delta and Epsilon). Instead it plays a more limited role in replication.".
- DNA_polymerase_alpha label "DNA polymerase alpha".
- DNA_polymerase_alpha sameAs DNA_polymeráza_α.
- DNA_polymerase_alpha sameAs ADN_polymérase_alpha.
- DNA_polymerase_alpha sameAs ADN_polimerase_alfa.
- DNA_polymerase_alpha sameAs Complesso_DNA_polimerasi_α-primasi.
- DNA_polymerase_alpha sameAs m.012dyktq.
- DNA_polymerase_alpha sameAs Q3500847.
- DNA_polymerase_alpha sameAs Q3500847.
- DNA_polymerase_alpha wasDerivedFrom DNA_polymerase_alpha?oldid=638317832.
- DNA_polymerase_alpha isPrimaryTopicOf DNA_polymerase_alpha.
- DNA_polymerase_alpha name "DNA-directed DNA polymerase".