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- DNA_fragmentation abstract "DNA fragmentation is the separation or breaking of DNA strands into pieces. It can be done intentionally by laboratory personnel or by cells, or can occur spontaneously. Spontaneous or accidental DNA fragmentation is fragmentation that gradually accumulates in a cell. It can be measured by e.g. the Comet assay.The degree of DNA fragmentation can predict outcomes for in vitro fertilization (IVF) and its expansion intracytoplasmic sperm injection (ICSI). The sperm chromatin dispersion test (SCD) and TUNEL assay are both effective in detecting sperm DNA damage. Using bright-field microscopy, the SCD test appears to be more sensitive than the TUNEL assay.Its main units of measurement is the DNA Fragmentation Index (DFI). A DFI of 20% or more significantly reduces the success rates after ICSI.DNA fragmentation was first documented by Williamson in 1970 when he observed discrete oligomeric fragments occurring during cell death in primary neonatal liver cultures. He described the cytoplasmic DNA isolated from mouse liver cells after culture as characterized by DNA fragments with a molecular weight consisting of multiples of 135 kDa. This finding was consistent with the hypothesis that these DNA fragments were a specific degradation product of nuclear DNA.".
- DNA_fragmentation thumbnail Complete_Histone_with_DNA.png?width=300.
- DNA_fragmentation wikiPageID "1822649".
- DNA_fragmentation wikiPageLength "9673".
- DNA_fragmentation wikiPageOutDegree "25".
- DNA_fragmentation wikiPageRevisionID "647812358".
- DNA_fragmentation wikiPageWikiLink Apoptosis.
- DNA_fragmentation wikiPageWikiLink Apoptotic_DNA_fragmentation.
- DNA_fragmentation wikiPageWikiLink Atomic_mass_unit.
- DNA_fragmentation wikiPageWikiLink Base_pair.
- DNA_fragmentation wikiPageWikiLink Base_pairs.
- DNA_fragmentation wikiPageWikiLink Bright-field_microscopy.
- DNA_fragmentation wikiPageWikiLink Caspase-activated_DNase.
- DNA_fragmentation wikiPageWikiLink Category:DNA.
- DNA_fragmentation wikiPageWikiLink Comet_assay.
- DNA_fragmentation wikiPageWikiLink DFFA.
- DNA_fragmentation wikiPageWikiLink DNA.
- DNA_fragmentation wikiPageWikiLink DNA_profiling.
- DNA_fragmentation wikiPageWikiLink French_pressure_cell_press.
- DNA_fragmentation wikiPageWikiLink Gel_electrophoresis.
- DNA_fragmentation wikiPageWikiLink In_vitro_fertilisation.
- DNA_fragmentation wikiPageWikiLink In_vitro_fertilization.
- DNA_fragmentation wikiPageWikiLink Inhibitor_of_caspase-activated_DNase.
- DNA_fragmentation wikiPageWikiLink Intracytoplasmic_sperm_injection.
- DNA_fragmentation wikiPageWikiLink KDa.
- DNA_fragmentation wikiPageWikiLink Nebulizer.
- DNA_fragmentation wikiPageWikiLink Restriction_Fragment_Length_Polymorphism.
- DNA_fragmentation wikiPageWikiLink Restriction_digest.
- DNA_fragmentation wikiPageWikiLink Restriction_endonuclease.
- DNA_fragmentation wikiPageWikiLink Restriction_enzyme.
- DNA_fragmentation wikiPageWikiLink Restriction_fragment_length_polymorphism.
- DNA_fragmentation wikiPageWikiLink Sonication.
- DNA_fragmentation wikiPageWikiLink Sperm_chromatin_dispersion.
- DNA_fragmentation wikiPageWikiLink Subcloning.
- DNA_fragmentation wikiPageWikiLink TUNEL_assay.
- DNA_fragmentation wikiPageWikiLink Units_of_measurement.
- DNA_fragmentation wikiPageWikiLink File:Complete_Histone_with_DNA.png.
- DNA_fragmentation wikiPageWikiLinkText "DNA cleavage".
- DNA_fragmentation wikiPageWikiLinkText "DNA fragmentation".
- DNA_fragmentation wikiPageWikiLinkText "fragment".
- DNA_fragmentation wikiPageWikiLinkText "fragmentation".
- DNA_fragmentation hasPhotoCollection DNA_fragmentation.
- DNA_fragmentation wikiPageUsesTemplate Template:Reflist.
- DNA_fragmentation subject Category:DNA.
- DNA_fragmentation hypernym Separation.
- DNA_fragmentation type Disease.
- DNA_fragmentation comment "DNA fragmentation is the separation or breaking of DNA strands into pieces. It can be done intentionally by laboratory personnel or by cells, or can occur spontaneously. Spontaneous or accidental DNA fragmentation is fragmentation that gradually accumulates in a cell. It can be measured by e.g. the Comet assay.The degree of DNA fragmentation can predict outcomes for in vitro fertilization (IVF) and its expansion intracytoplasmic sperm injection (ICSI).".
- DNA_fragmentation label "DNA fragmentation".
- DNA_fragmentation sameAs Frammentazione_del_DNA.
- DNA_fragmentation sameAs m.0cc5y88.
- DNA_fragmentation sameAs Q3749256.
- DNA_fragmentation sameAs Q3749256.
- DNA_fragmentation wasDerivedFrom DNA_fragmentation?oldid=647812358.
- DNA_fragmentation depiction Complete_Histone_with_DNA.png.
- DNA_fragmentation isPrimaryTopicOf DNA_fragmentation.