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- Cymserine abstract "Cymserine is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity (15×) for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of the better-known acetylcholinesterase enzyme. This gives it a much more specific profile of effects that may be useful for treating Alzheimer's disease without producing side effects such as tremors, lacrimation, and salivation that are seen with the older nonselective cholinesterase inhibitors currently used for this application, such as donepezil. A number of cymserine derivatives have been developed with much greater selectivity for butyrylcholinesterase, and both cymserine and several of its analogues have been tested in animals, and found to increase brain acetylcholine levels and produce nootropic effects, as well as reducing levels of amyloid precursor protein and amyloid beta, which are commonly used biomarkers for the development of Alzheimer's disease.".
- Cymserine casNumber "145209-39-8".
- Cymserine iupacName "((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl)-4-isopropylphenylcarbamate".
- Cymserine pubchem "9907847".
- Cymserine thumbnail Cymserine_structure.png?width=300.
- Cymserine wikiPageID "31770614".
- Cymserine wikiPageLength "4221".
- Cymserine wikiPageOutDegree "19".
- Cymserine wikiPageRevisionID "676317123".
- Cymserine wikiPageWikiLink Acetylcholine.
- Cymserine wikiPageWikiLink Acetylcholinesterase.
- Cymserine wikiPageWikiLink Acetylcholinesterase_inhibitor.
- Cymserine wikiPageWikiLink Alzheimers_disease.
- Cymserine wikiPageWikiLink Amyloid_beta.
- Cymserine wikiPageWikiLink Amyloid_precursor_protein.
- Cymserine wikiPageWikiLink Butyrylcholinesterase.
- Cymserine wikiPageWikiLink Category:Alkaloids.
- Cymserine wikiPageWikiLink Category:Carbamates.
- Cymserine wikiPageWikiLink Category:Indole_alkaloids.
- Cymserine wikiPageWikiLink Category:Pyrroloindoles.
- Cymserine wikiPageWikiLink Cholinesterase_inhibitor.
- Cymserine wikiPageWikiLink Donepezil.
- Cymserine wikiPageWikiLink Lacrimation.
- Cymserine wikiPageWikiLink Nootropic.
- Cymserine wikiPageWikiLink Physostigmine.
- Cymserine wikiPageWikiLink Saliva.
- Cymserine wikiPageWikiLink Salivation.
- Cymserine wikiPageWikiLink Tears.
- Cymserine wikiPageWikiLink Tremor.
- Cymserine wikiPageWikiLink Category:Butyrylcholinesterase_inhibitors.
- Cymserine wikiPageWikiLink File:Cymserine_derivs.png.
- Cymserine wikiPageWikiLinkText "Cymserine".
- Cymserine c "23".
- Cymserine casNumber "145209".
- Cymserine chemspiderid "26000641".
- Cymserine h "29".
- Cymserine hasPhotoCollection Cymserine.
- Cymserine iupacName "-4".
- Cymserine molecularWeight "379.495".
- Cymserine n "3".
- Cymserine o "2".
- Cymserine pubchem "9907847".
- Cymserine smiles "C[C@@]12[C@@]NC3=CC=CC=C31".
- Cymserine stdinchi "1".
- Cymserine stdinchikey "WHFRVERUBMJQSO-GHTZIAJQSA-N".
- Cymserine verifiedrevid "430522824".
- Cymserine width "220".
- Cymserine wikiPageUsesTemplate Template:Antidementia.
- Cymserine wikiPageUsesTemplate Template:Cholinergics.
- Cymserine wikiPageUsesTemplate Template:Drugbox.
- Cymserine wikiPageUsesTemplate Template:Reflist.
- Cymserine subject Category:Alkaloids.
- Cymserine subject Category:Carbamates.
- Cymserine subject Category:Indole_alkaloids.
- Cymserine subject Category:Pyrroloindoles.
- Cymserine subject Category:Butyrylcholinesterase_inhibitors.
- Cymserine hypernym Drug.
- Cymserine type Article.
- Cymserine type Biomolecule.
- Cymserine type ChemicalSubstance.
- Cymserine type Drug.
- Cymserine type Alkaloid.
- Cymserine type Amide.
- Cymserine type Article.
- Cymserine type Biomolecule.
- Cymserine type Carbamate.
- Cymserine type Ester.
- Cymserine type Heterocycle.
- Cymserine type ChemicalObject.
- Cymserine type Thing.
- Cymserine type Q8386.
- Cymserine comment "Cymserine is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity (15×) for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of the better-known acetylcholinesterase enzyme.".
- Cymserine label "Cymserine".
- Cymserine sameAs Cymserina.
- Cymserine sameAs m.0gttb5t.
- Cymserine sameAs Cimserin.
- Cymserine sameAs Cimserin.
- Cymserine sameAs Q5199864.
- Cymserine sameAs Q5199864.
- Cymserine wasDerivedFrom Cymserine?oldid=676317123.
- Cymserine depiction Cymserine_structure.png.
- Cymserine isPrimaryTopicOf Cymserine.