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- Costamere abstract "The costamere is a structural-functional component of striated muscle cells which connects the sarcomere of the muscle to the cell membrane.Costameres are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils. They physically couple force-generating sarcomeres with the sarcolemma in striated muscle cells and are thus considered one of several "Achilles' heels" of skeletal muscle, a critical component of striated muscle morphology which, when compromised, is thought to directly contribute to the development of several distinct myopathies.The dystrophin-associated glycoprotein (DAG) complex contains various integral and peripheral membrane proteins such as dystroglycans and sarcoglycans, which are thought to be responsible for linking the internal cytoskeletal system of individual myofibers to structural proteins within the extracellular matrix (such as collagen and laminin). Therefore, it is one of the features of the sarcolemma which helps to couple the sarcomere to the extracellular connective tissue as some experiments have shown. Desmin protein may also bind to the DAG complex, and regions of it are known to be involved in signaling.".
- Costamere meshName "Costameres".
- Costamere thumbnail Costamere_structure_in_mouse_quadriceps_-_journal.pone.0002604.g003-cropped.png?width=300.
- Costamere wikiPageID "8541878".
- Costamere wikiPageLength "3122".
- Costamere wikiPageOutDegree "14".
- Costamere wikiPageRevisionID "683763141".
- Costamere wikiPageWikiLink Achilles_heel.
- Costamere wikiPageWikiLink Category:Histology.
- Costamere wikiPageWikiLink Collagen.
- Costamere wikiPageWikiLink Dystroglycan.
- Costamere wikiPageWikiLink Dystroglycans.
- Costamere wikiPageWikiLink Laminin.
- Costamere wikiPageWikiLink Myofibril.
- Costamere wikiPageWikiLink Myopathies.
- Costamere wikiPageWikiLink Myopathy.
- Costamere wikiPageWikiLink Sarcoglycan.
- Costamere wikiPageWikiLink Sarcoglycans.
- Costamere wikiPageWikiLink Sarcolemma.
- Costamere wikiPageWikiLink Sarcomere.
- Costamere wikiPageWikiLink Striated_muscle.
- Costamere wikiPageWikiLink Striated_muscle_tissue.
- Costamere wikiPageWikiLink Z-disk.
- Costamere wikiPageWikiLink File:Costamere_structure_in_mouse_quadriceps_-_journal.pone.0002604.g003-cropped.png.
- Costamere wikiPageWikiLinkText "Costamere".
- Costamere wikiPageWikiLinkText "DPC".
- Costamere wikiPageWikiLinkText "costamere".
- Costamere wikiPageWikiLinkText "costameric".
- Costamere hasPhotoCollection Costamere.
- Costamere latin "costamerum".
- Costamere meshname "Costameres".
- Costamere name "Costamere".
- Costamere wikiPageUsesTemplate Template:Cell-biology-stub.
- Costamere wikiPageUsesTemplate Template:Epithelial_tissue.
- Costamere wikiPageUsesTemplate Template:Infobox_anatomy.
- Costamere wikiPageUsesTemplate Template:Muscle_tissue.
- Costamere wikiPageUsesTemplate Template:Reflist.
- Costamere subject Category:Histology.
- Costamere hypernym Component.
- Costamere type AnatomicalStructure.
- Costamere type MilitaryUnit.
- Costamere type Thing.
- Costamere type Q4936952.
- Costamere comment "The costamere is a structural-functional component of striated muscle cells which connects the sarcomere of the muscle to the cell membrane.Costameres are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils.".
- Costamere label "Costamere".
- Costamere sameAs Costamer.
- Costamere sameAs Costámero.
- Costamere sameAs Costâmero.
- Costamere sameAs m.02776mr.
- Costamere sameAs Q1136436.
- Costamere sameAs Q1136436.
- Costamere wasDerivedFrom Costamere?oldid=683763141.
- Costamere depiction Costamere_structure_in_mouse_quadriceps_-_journal.pone.0002604.g003-cropped.png.
- Costamere isPrimaryTopicOf Costamere.
- Costamere name "Costamere".