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- Corticotropin-releasing_factor_family abstract "Corticotropin-releasing factor, CRF is a family of related neuropeptides in vertebrates. This family includes corticotropin-releasing hormone, urotensin-I, urocortin, and sauvagine. The family can be grouped into 2 separate paralogous lineages, with urotensin-I, urocortin and sauvagine in one group and CRH forming the other group. Urocortin and sauvagine appear to represent orthologues of fish urotensin-I in mammals and amphibians, respectively. The peptides have a variety of physiological effects on stress and anxiety, vasoregulation, thermoregulation, growth and metabolism, metamorphosis and reproduction in various species, and are all released as prohormones.Corticotropin-releasing hormone (CRH) is a hormone found mainly in the paraventricular nucleus of the mammalian hypothalamus that regulates the release of corticotropin (ACTH) from the pituitary gland. The paraventricular nucleus transports CRH to the anterior pituitary, stimulating adrenocorticotropic hormone (ACTH) release via CRH type 1 receptors, thereby activating the hypothalamic-pituitary-adrenal axis (HPA) and, thus, glucocorticoid release.CRH is evolutionary-related to a number of other active peptides. Urocortin acts in vitro to stimulate the secretion of adrenocorticotropic hormone. Urotensin is found in the teleost caudal neurosecretory system and may play a role in osmoregulation and as a corticotropin-releasing factor. Urotensin-I is released from the urophysis of fish, and produces ACTH and subsequent cortisol release in vivo. The nonhormonal portion of the prohormone is thought to be the urotensin binding protein (urophysin). Sauvagine (P01144), isolated from frog skin, has a potent hypotensive and diuretic effect.".
- Corticotropin-releasing_factor_family symbol "CRF".
- Corticotropin-releasing_factor_family wikiPageID "356729".
- Corticotropin-releasing_factor_family wikiPageLength "3168".
- Corticotropin-releasing_factor_family wikiPageOutDegree "42".
- Corticotropin-releasing_factor_family wikiPageRevisionID "596685505".
- Corticotropin-releasing_factor_family wikiPageWikiLink Adrenocorticotropic_hormone.
- Corticotropin-releasing_factor_family wikiPageWikiLink Anterior_pituitary.
- Corticotropin-releasing_factor_family wikiPageWikiLink Anxiety.
- Corticotropin-releasing_factor_family wikiPageWikiLink Category:Hormones.
- Corticotropin-releasing_factor_family wikiPageWikiLink Category:Protein_domains.
- Corticotropin-releasing_factor_family wikiPageWikiLink Caudal_neurosecretory_system.
- Corticotropin-releasing_factor_family wikiPageWikiLink Corticotropin.
- Corticotropin-releasing_factor_family wikiPageWikiLink Corticotropin-releasing_hormone.
- Corticotropin-releasing_factor_family wikiPageWikiLink Corticotropin-releasing_hormone_receptor_1.
- Corticotropin-releasing_factor_family wikiPageWikiLink Cortisol.
- Corticotropin-releasing_factor_family wikiPageWikiLink Diuretic.
- Corticotropin-releasing_factor_family wikiPageWikiLink Diuretic_hormone.
- Corticotropin-releasing_factor_family wikiPageWikiLink Glucocorticoid.
- Corticotropin-releasing_factor_family wikiPageWikiLink Homology_(biology).
- Corticotropin-releasing_factor_family wikiPageWikiLink Hypotension.
- Corticotropin-releasing_factor_family wikiPageWikiLink Hypotensive.
- Corticotropin-releasing_factor_family wikiPageWikiLink Hypothalamic-pituitary-adrenal_axis.
- Corticotropin-releasing_factor_family wikiPageWikiLink Hypothalamic–pituitary–adrenal_axis.
- Corticotropin-releasing_factor_family wikiPageWikiLink Hypothalamus.
- Corticotropin-releasing_factor_family wikiPageWikiLink Neuropeptide.
- Corticotropin-releasing_factor_family wikiPageWikiLink Osmoregulation.
- Corticotropin-releasing_factor_family wikiPageWikiLink Paralog.
- Corticotropin-releasing_factor_family wikiPageWikiLink Paraventricular_nucleus.
- Corticotropin-releasing_factor_family wikiPageWikiLink Paraventricular_nucleus_of_hypothalamus.
- Corticotropin-releasing_factor_family wikiPageWikiLink Pituitary_gland.
- Corticotropin-releasing_factor_family wikiPageWikiLink Prohormone.
- Corticotropin-releasing_factor_family wikiPageWikiLink Prohormones.
- Corticotropin-releasing_factor_family wikiPageWikiLink Protein_family.
- Corticotropin-releasing_factor_family wikiPageWikiLink Sauvagine.
- Corticotropin-releasing_factor_family wikiPageWikiLink Teleost.
- Corticotropin-releasing_factor_family wikiPageWikiLink Teleostei.
- Corticotropin-releasing_factor_family wikiPageWikiLink Thermoregulation.
- Corticotropin-releasing_factor_family wikiPageWikiLink Urocortin.
- Corticotropin-releasing_factor_family wikiPageWikiLink Urophysin.
- Corticotropin-releasing_factor_family wikiPageWikiLink Urophysis.
- Corticotropin-releasing_factor_family wikiPageWikiLink Urotensin-II.
- Corticotropin-releasing_factor_family wikiPageWikiLink Vasoregulation.
- Corticotropin-releasing_factor_family wikiPageWikiLink Vertebrate.
- Corticotropin-releasing_factor_family wikiPageWikiLinkText "CRF".
- Corticotropin-releasing_factor_family wikiPageWikiLinkText "Corticotropin-releasing factor family".
- Corticotropin-releasing_factor_family wikiPageWikiLinkText "corticotropin-releasing factor family".
- Corticotropin-releasing_factor_family hasPhotoCollection Corticotropin-releasing_factor_family.
- Corticotropin-releasing_factor_family interpro "IPR000187".
- Corticotropin-releasing_factor_family name "Corticotropin-releasing factor family".
- Corticotropin-releasing_factor_family pfam "PF00473".
- Corticotropin-releasing_factor_family prosite "PDOC00442".
- Corticotropin-releasing_factor_family scop "1".
- Corticotropin-releasing_factor_family symbol "CRF".
- Corticotropin-releasing_factor_family wikiPageUsesTemplate Template:InterPro.
- Corticotropin-releasing_factor_family wikiPageUsesTemplate Template:InterPro_content.
- Corticotropin-releasing_factor_family wikiPageUsesTemplate Template:Pfam_box.
- Corticotropin-releasing_factor_family wikiPageUsesTemplate Template:Reflist.
- Corticotropin-releasing_factor_family wikiPageUsesTemplate Template:Uniprot.
- Corticotropin-releasing_factor_family subject Category:Hormones.
- Corticotropin-releasing_factor_family subject Category:Protein_domains.
- Corticotropin-releasing_factor_family hypernym Family.
- Corticotropin-releasing_factor_family type Biomolecule.
- Corticotropin-releasing_factor_family type Protein.
- Corticotropin-releasing_factor_family type Biomolecule.
- Corticotropin-releasing_factor_family type Domain.
- Corticotropin-releasing_factor_family type Thing.
- Corticotropin-releasing_factor_family type Q206229.
- Corticotropin-releasing_factor_family type Q8054.
- Corticotropin-releasing_factor_family comment "Corticotropin-releasing factor, CRF is a family of related neuropeptides in vertebrates. This family includes corticotropin-releasing hormone, urotensin-I, urocortin, and sauvagine. The family can be grouped into 2 separate paralogous lineages, with urotensin-I, urocortin and sauvagine in one group and CRH forming the other group. Urocortin and sauvagine appear to represent orthologues of fish urotensin-I in mammals and amphibians, respectively.".
- Corticotropin-releasing_factor_family label "Corticotropin-releasing factor family".
- Corticotropin-releasing_factor_family sameAs العامل_المطلق_لموجهة_القشرة.
- Corticotropin-releasing_factor_family sameAs m.0dlkmv3.
- Corticotropin-releasing_factor_family sameAs Q5173291.
- Corticotropin-releasing_factor_family sameAs Q5173291.
- Corticotropin-releasing_factor_family wasDerivedFrom Corticotropin-releasing_factor_family?oldid=596685505.
- Corticotropin-releasing_factor_family isPrimaryTopicOf Corticotropin-releasing_factor_family.