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- Controlled_release abstract "Controlled release is a term referring to the presentation or delivery of compounds in response to stimuli or time. This can be for purposes in several areas including agriculture, cosmetics and personal care, pharmaceuticals and food science. Most commonly it refers to time dependent release in oral dose formulations. Timed release has several distinct variants such assustained release where prolonged release is intended, pulse release, delayed release (e.g. to target different regions of the GI tract) etc. A distinction of controlled release is that not only prolongs action but it attempts to maintain drug levels within the therapeutic window to avoid potentially hazardous peaks in drug concentration following ingestion or injection and to maximize therapeutic efficiency.The science of controlled release originates from the development of oral sustained-release products in the late 1940s and early 1950s, the development of controlled release of marine anti-foulants in the 1950s and controlled release fertilizer in the 1970s where sustained and controlled delivery of nutrients following a single application to the soil. Delivery is usually effected by dissolution, degradation or disintegration of an excipient in which the active compound is formulated. Enteric coating and other encapsulation technologies can further modify release profiles.In addition to pills, capsules and injectable drug carriers (that often have an additional release function), forms of controlled release medicines include gels, implants and devices (e.g. the Vaginal ring and contraceptive implant) and transdermal patches.Examples of stimuli that may be used to bring about release include pH, enzymes, light, magnetic fields, temperature, ultrasonics, osmosis and more recently electronic control of MEMS and NEMS.Examples of cosmetics, personal care and food science applications often centre on odour or flavour release.The release technology scientific and industrial community is represented by the Controlled Release Society (CRS). The CRS is the worldwide society for delivery science and technologies. CRS serves more than 1,600 members from more than 50 countries. Two-thirds of CRS membership is represented by industry and one-third represents academia and government. CRS is affiliated with the Journal of Controlled Release and Drug Delivery and Translational Research scientific journals.".
- Controlled_release wikiPageExternalLink controlled_release_technology.html.
- Controlled_release wikiPageExternalLink default.aspx.
- Controlled_release wikiPageExternalLink www.ukicrs.org.
- Controlled_release wikiPageID "9360334".
- Controlled_release wikiPageLength "3618".
- Controlled_release wikiPageOutDegree "16".
- Controlled_release wikiPageRevisionID "672885306".
- Controlled_release wikiPageWikiLink Category:Drug_delivery_devices.
- Controlled_release wikiPageWikiLink Category:Routes_of_administration.
- Controlled_release wikiPageWikiLink Contraceptive_implant.
- Controlled_release wikiPageWikiLink Controlled-release_fertiliser.
- Controlled_release wikiPageWikiLink Controlled_release_fertilizer.
- Controlled_release wikiPageWikiLink Drug_carrier.
- Controlled_release wikiPageWikiLink Drug_carriers.
- Controlled_release wikiPageWikiLink Enteric_coating.
- Controlled_release wikiPageWikiLink Excipient.
- Controlled_release wikiPageWikiLink Journal_of_Controlled_Release.
- Controlled_release wikiPageWikiLink MEMS.
- Controlled_release wikiPageWikiLink Microelectromechanical_systems.
- Controlled_release wikiPageWikiLink Nanoelectromechanical_systems.
- Controlled_release wikiPageWikiLink Sustained_release.
- Controlled_release wikiPageWikiLink Therapeutic_index.
- Controlled_release wikiPageWikiLink Therapeutic_window.
- Controlled_release wikiPageWikiLink Time_release_technology.
- Controlled_release wikiPageWikiLink Transdermal_patch.
- Controlled_release wikiPageWikiLink Transdermal_patches.
- Controlled_release wikiPageWikiLink Vaginal_ring.
- Controlled_release wikiPageWikiLinkText "Controlled release".
- Controlled_release wikiPageWikiLinkText "control release".
- Controlled_release wikiPageWikiLinkText "controlled release".
- Controlled_release wikiPageWikiLinkText "controlled-release".
- Controlled_release wikiPageWikiLinkText "slow-releasing".
- Controlled_release hasPhotoCollection Controlled_release.
- Controlled_release wikiPageUsesTemplate Template:Mergeto.
- Controlled_release wikiPageUsesTemplate Template:Pharma-stub.
- Controlled_release wikiPageUsesTemplate Template:Reflist.
- Controlled_release subject Category:Drug_delivery_devices.
- Controlled_release subject Category:Routes_of_administration.
- Controlled_release hypernym Term.
- Controlled_release type Article.
- Controlled_release type Drug.
- Controlled_release type Article.
- Controlled_release type Drug.
- Controlled_release type Route.
- Controlled_release comment "Controlled release is a term referring to the presentation or delivery of compounds in response to stimuli or time. This can be for purposes in several areas including agriculture, cosmetics and personal care, pharmaceuticals and food science. Most commonly it refers to time dependent release in oral dose formulations. Timed release has several distinct variants such assustained release where prolonged release is intended, pulse release, delayed release (e.g.".
- Controlled_release label "Controlled release".
- Controlled_release sameAs m.0h56ky9.
- Controlled_release sameAs Q5165929.
- Controlled_release sameAs Q5165929.
- Controlled_release wasDerivedFrom Controlled_release?oldid=672885306.
- Controlled_release isPrimaryTopicOf Controlled_release.