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- Codocyte abstract "Codocytes, also known as target cells or Mexican hat cells, are red blood cells that have the appearance of a shooting target with a bullseye. In optical microscopy these cells appear to have a dark center (a central, hemoglobinized area) surrounded by a white ring (an area of relative pallor), followed by dark outer (peripheral) second ring containing a band of hemoglobin. However in electron microscopy they appear very thin and bell shaped. Because of their thinness they are referred to as leptocytes and because of the wavy bowl shape they are referred to as Mexican hat cells. On routine smear morphology, some people like to make a distinction between leptocyes and codocytes- suggesting that in leptocytes the central spot is not completely detached from the peripheral ring, i.e. the pallor is in a C shape rather than a full ring.These cells are characterized by a disproportional increase in the ratio of surface membrane area to volume. This is also described as a "relative membrane excess." It is due to either increased red cell surface area (increased beyond normal), or else a decreased intracellular hemoglobin content (which may cause an abnormal decrease in cell volume without affecting the amount of membrane area). The increase in the surface area to volume ratio also gives the cell decreased osmotic fragility, as it allows it to take up more water for a given amount of osmotic stress.In vivo (within the blood vessel), the codocyte is a bell-shaped cell. It assumes a "target" configuration only when processed to obtain a blood film. In the film these cells appear thinner than normal, primarily due to their pallor (by which thickness is judged on microscopy).".
- Codocyte thumbnail Target_cells_and_spherocytes.jpg?width=300.
- Codocyte wikiPageExternalLink arbl.cvmbs.colostate.edu.
- Codocyte wikiPageExternalLink LB2.html.
- Codocyte wikiPageExternalLink www.ornl.gov.
- Codocyte wikiPageID "2929810".
- Codocyte wikiPageLength "5118".
- Codocyte wikiPageOutDegree "14".
- Codocyte wikiPageRevisionID "677048662".
- Codocyte wikiPageWikiLink Alpha-thalassemia.
- Codocyte wikiPageWikiLink Autosplenectomy.
- Codocyte wikiPageWikiLink Beta-thalassemia.
- Codocyte wikiPageWikiLink Beta_thalassemia.
- Codocyte wikiPageWikiLink Biological_membrane.
- Codocyte wikiPageWikiLink Bullseye_(target).
- Codocyte wikiPageWikiLink Category:Abnormal_clinical_and_laboratory_findings_for_RBCs.
- Codocyte wikiPageWikiLink Hemoglobin_C.
- Codocyte wikiPageWikiLink Lecithin—cholesterol_acyltransferase.
- Codocyte wikiPageWikiLink Liver_disease.
- Codocyte wikiPageWikiLink Macrophage.
- Codocyte wikiPageWikiLink Opsonin.
- Codocyte wikiPageWikiLink Sickle-cell_disease.
- Codocyte wikiPageWikiLink Sickle_cell_anemia.
- Codocyte wikiPageWikiLink Splenectomy.
- Codocyte wikiPageWikiLink File:Target_cells_and_spherocytes.jpg.
- Codocyte wikiPageWikiLinkText "Codocyte".
- Codocyte wikiPageWikiLinkText "Target cell".
- Codocyte wikiPageWikiLinkText "codocyte".
- Codocyte wikiPageWikiLinkText "target cells".
- Codocyte hasPhotoCollection Codocyte.
- Codocyte wikiPageUsesTemplate Template:Abnormal_clinical_and_laboratory_findings.
- Codocyte wikiPageUsesTemplate Template:Citation_needed.
- Codocyte wikiPageUsesTemplate Template:Reflist.
- Codocyte subject Category:Abnormal_clinical_and_laboratory_findings_for_RBCs.
- Codocyte hypernym Cells.
- Codocyte type AnatomicalStructure.
- Codocyte type Article.
- Codocyte type Article.
- Codocyte comment "Codocytes, also known as target cells or Mexican hat cells, are red blood cells that have the appearance of a shooting target with a bullseye. In optical microscopy these cells appear to have a dark center (a central, hemoglobinized area) surrounded by a white ring (an area of relative pallor), followed by dark outer (peripheral) second ring containing a band of hemoglobin. However in electron microscopy they appear very thin and bell shaped.".
- Codocyte label "Codocyte".
- Codocyte sameAs Codocyte.
- Codocyte sameAs Target_cells.
- Codocyte sameAs m.08dc53.
- Codocyte sameAs Q3515681.
- Codocyte sameAs Q3515681.
- Codocyte wasDerivedFrom Codocyte?oldid=677048662.
- Codocyte depiction Target_cells_and_spherocytes.jpg.
- Codocyte isPrimaryTopicOf Codocyte.