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- Chemical_genetics abstract "Chemical genetics is the investigation of proteins and signal transduction pathways by the screening of chemical libraries of small molecules. Chemical genetics is analogous to classical genetics where random mutations are introduced in organisms, the phenotype of these mutants is observed, and finally the specific gene mutation (genotype) that produced that phenotype is identified. In chemical genetics, the phenotype is disturbed not by introduction of mutations, but by exposure to small molecules (drug candidates). Phenotypic screening of chemical libraries is used to identify drug targets (forward chemical genetics) or to validate those targets in experimental models of disease (reverse chemical genetics). Recent applications of this topic have been implicated in signal transduction, which may play a role in discovering new cancer treatments.".
- Chemical_genetics wikiPageID "36436244".
- Chemical_genetics wikiPageLength "3334".
- Chemical_genetics wikiPageOutDegree "13".
- Chemical_genetics wikiPageRevisionID "661528393".
- Chemical_genetics wikiPageWikiLink Category:Genetics.
- Chemical_genetics wikiPageWikiLink Chemical_biology.
- Chemical_genetics wikiPageWikiLink Chemical_library.
- Chemical_genetics wikiPageWikiLink Chemogenomics.
- Chemical_genetics wikiPageWikiLink Genetics.
- Chemical_genetics wikiPageWikiLink Genotype.
- Chemical_genetics wikiPageWikiLink High-throughput_screening.
- Chemical_genetics wikiPageWikiLink Phenotype.
- Chemical_genetics wikiPageWikiLink Phenotypic_screening.
- Chemical_genetics wikiPageWikiLink Protein.
- Chemical_genetics wikiPageWikiLink Signal_transduction.
- Chemical_genetics wikiPageWikiLink Small_molecule.
- Chemical_genetics wikiPageWikiLinkText "Chemical genetics".
- Chemical_genetics wikiPageWikiLinkText "chemical genetics".
- Chemical_genetics hasPhotoCollection Chemical_genetics.
- Chemical_genetics wikiPageUsesTemplate Template:Pharma-stub.
- Chemical_genetics wikiPageUsesTemplate Template:Reflist.
- Chemical_genetics subject Category:Genetics.
- Chemical_genetics hypernym Investigation.
- Chemical_genetics type Work.
- Chemical_genetics comment "Chemical genetics is the investigation of proteins and signal transduction pathways by the screening of chemical libraries of small molecules. Chemical genetics is analogous to classical genetics where random mutations are introduced in organisms, the phenotype of these mutants is observed, and finally the specific gene mutation (genotype) that produced that phenotype is identified.".
- Chemical_genetics label "Chemical genetics".
- Chemical_genetics sameAs m.0k96kbl.
- Chemical_genetics sameAs Q5090466.
- Chemical_genetics sameAs Q5090466.
- Chemical_genetics wasDerivedFrom Chemical_genetics?oldid=661528393.
- Chemical_genetics isPrimaryTopicOf Chemical_genetics.