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- Carbon_monoxide-releasing_molecules abstract "Carbon monoxide-releasing molecules (CO-RMs) are chemical compounds that release controlled amounts of carbon monoxide (CO) to cells and tissues and are being developed as potential therapeutic agents. Although long recognized as a poison, CO also exhibits beneficial effects in small doses. These effects include anti-inflammatory activity, vasodilatation, and cardioprotection. CO is produced in mammals during the degradation of heme by heme oxygenase-1, a redox-sensitive enzyme induced by oxidative stress. It is this enzymatic reaction that inspired the development of synthetic CO-RMs.Synthetic CO-RMs are typically metal carbonyl complexes. A representative CO-RM that has been extensively characterized both from a biochemical and pharmacological view point is the ruthenium(II) complex Ru(glycinate)Cl(CO)3, also known as CORM-3.".
- Carbon_monoxide-releasing_molecules thumbnail RuCl(gly)(CO)3.png?width=300.
- Carbon_monoxide-releasing_molecules wikiPageID "43083758".
- Carbon_monoxide-releasing_molecules wikiPageLength "2095".
- Carbon_monoxide-releasing_molecules wikiPageOutDegree "8".
- Carbon_monoxide-releasing_molecules wikiPageRevisionID "622705062".
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Anti-inflammatory.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Carbon_monoxide.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Category:Carbonyl_complexes.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Glycinate.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Glycine.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Heme_oxygenase.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Metal_carbonyl.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Metal_carbonyl_complex.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink Oxidative_stress.
- Carbon_monoxide-releasing_molecules wikiPageWikiLink File:RuCl(gly)(CO)3.png.
- Carbon_monoxide-releasing_molecules wikiPageWikiLinkText "Carbon monoxide-releasing molecules".
- Carbon_monoxide-releasing_molecules hasPhotoCollection Carbon_monoxide-releasing_molecules.
- Carbon_monoxide-releasing_molecules subject Category:Carbonyl_complexes.
- Carbon_monoxide-releasing_molecules hypernym Compounds.
- Carbon_monoxide-releasing_molecules type ChemicalCompound.
- Carbon_monoxide-releasing_molecules comment "Carbon monoxide-releasing molecules (CO-RMs) are chemical compounds that release controlled amounts of carbon monoxide (CO) to cells and tissues and are being developed as potential therapeutic agents. Although long recognized as a poison, CO also exhibits beneficial effects in small doses. These effects include anti-inflammatory activity, vasodilatation, and cardioprotection.".
- Carbon_monoxide-releasing_molecules label "Carbon monoxide-releasing molecules".
- Carbon_monoxide-releasing_molecules sameAs m.010xc0k5.
- Carbon_monoxide-releasing_molecules sameAs Q18343452.
- Carbon_monoxide-releasing_molecules sameAs Q18343452.
- Carbon_monoxide-releasing_molecules wasDerivedFrom Carbon_monoxide-releasing_molecules?oldid=622705062.
- Carbon_monoxide-releasing_molecules depiction RuCl(gly)(CO)3.png.
- Carbon_monoxide-releasing_molecules isPrimaryTopicOf Carbon_monoxide-releasing_molecules.