Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/CPEB> ?p ?o }
Showing triples 1 to 77 of
77
with 100 triples per page.
- CPEB abstract "CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine tail of messenger RNA. CPEB most commonly activates the target RNA for translation, but can also act as a repressor, dependent on its phosphorylation state. In animals, CPEB is expressed in several alternative splicing isoforms that are specific to particular tissues and functions, including the self-cleaving Mammalian CPEB3 ribozyme. CPEB was first identified in Xenopus oocytes and associated with meiosis; a role has also been identified in the spermatogenesis of Caenorhabditis elegans.CPEB is involved in closed-loop regulation of mRNAs that keeps them inactive. The closed-loop structure between the 3'UTR and 5'UTR inhibits translation. This has been observed in Xenopus laevis in which eIF4E bound to the 5' cap interacts with Maskin bound to CPEB on the 3' UTR creating translationally inactive transcripts. This translational inhibition is lifted once CPEB is phosphorylated, displacing the Maskin binding site, allowing for the polymerization of the PolyA tail, which can recruit the translational machinery by means of PABP. However, it is important to note that this mechanism has been under great scrutiny.".
- CPEB wikiPageID "11969499".
- CPEB wikiPageLength "7145".
- CPEB wikiPageOutDegree "44".
- CPEB wikiPageRevisionID "633171587".
- CPEB wikiPageWikiLink 3UTR.
- CPEB wikiPageWikiLink 3_UTR.
- CPEB wikiPageWikiLink 5UTR.
- CPEB wikiPageWikiLink 5_cap.
- CPEB wikiPageWikiLink African_clawed_frog.
- CPEB wikiPageWikiLink Alternative_splicing.
- CPEB wikiPageWikiLink Aplysia_californica.
- CPEB wikiPageWikiLink Biomolecular_structure.
- CPEB wikiPageWikiLink Caenorhabditis_elegans.
- CPEB wikiPageWikiLink California_sea_hare.
- CPEB wikiPageWikiLink Category:Memory.
- CPEB wikiPageWikiLink Category:RNA-binding_proteins.
- CPEB wikiPageWikiLink Conserved_sequence.
- CPEB wikiPageWikiLink Cytoplasmic_polyadenylation_element.
- CPEB wikiPageWikiLink Drosophila.
- CPEB wikiPageWikiLink EIF4E.
- CPEB wikiPageWikiLink EIF4EBP1.
- CPEB wikiPageWikiLink Five-prime_cap.
- CPEB wikiPageWikiLink Five_prime_untranslated_region.
- CPEB wikiPageWikiLink GLD-2.
- CPEB wikiPageWikiLink Heritability.
- CPEB wikiPageWikiLink Heritable.
- CPEB wikiPageWikiLink MRNA.
- CPEB wikiPageWikiLink Mammalian_CPEB3_ribozyme.
- CPEB wikiPageWikiLink Meiosis.
- CPEB wikiPageWikiLink Memory.
- CPEB wikiPageWikiLink Messenger_RNA.
- CPEB wikiPageWikiLink N-terminus.
- CPEB wikiPageWikiLink Neuron.
- CPEB wikiPageWikiLink Oocyte.
- CPEB wikiPageWikiLink PABPC1.
- CPEB wikiPageWikiLink PARN.
- CPEB wikiPageWikiLink PUM2.
- CPEB wikiPageWikiLink Phosphorylated.
- CPEB wikiPageWikiLink Phosphorylation.
- CPEB wikiPageWikiLink Poly(A)-specific_ribonuclease.
- CPEB wikiPageWikiLink PolyA-binding_protein.
- CPEB wikiPageWikiLink PolyA_tail.
- CPEB wikiPageWikiLink Polyadenylation.
- CPEB wikiPageWikiLink Polymerization.
- CPEB wikiPageWikiLink Prion.
- CPEB wikiPageWikiLink Protein.
- CPEB wikiPageWikiLink Protein-protein_interaction.
- CPEB wikiPageWikiLink Protein–protein_interaction.
- CPEB wikiPageWikiLink RNA.
- CPEB wikiPageWikiLink SYMPK.
- CPEB wikiPageWikiLink Spermatogenesis.
- CPEB wikiPageWikiLink Tertiary_structure.
- CPEB wikiPageWikiLink Three_prime_untranslated_region.
- CPEB wikiPageWikiLink Translation_(biology).
- CPEB wikiPageWikiLink Translation_(genetics).
- CPEB wikiPageWikiLink Xenopus.
- CPEB wikiPageWikiLink Xenopus_laevis.
- CPEB wikiPageWikiLink Yeast.
- CPEB wikiPageWikiLinkText "CPE binding protein".
- CPEB wikiPageWikiLinkText "CPEB".
- CPEB wikiPageWikiLinkText "CPEB3".
- CPEB hasPhotoCollection CPEB.
- CPEB wikiPageUsesTemplate Template:For.
- CPEB wikiPageUsesTemplate Template:Protein-stub.
- CPEB wikiPageUsesTemplate Template:Reflist.
- CPEB subject Category:Memory.
- CPEB subject Category:RNA-binding_proteins.
- CPEB type Article.
- CPEB type Article.
- CPEB comment "CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine tail of messenger RNA. CPEB most commonly activates the target RNA for translation, but can also act as a repressor, dependent on its phosphorylation state. In animals, CPEB is expressed in several alternative splicing isoforms that are specific to particular tissues and functions, including the self-cleaving Mammalian CPEB3 ribozyme.".
- CPEB label "CPEB".
- CPEB sameAs m.02r_2zh.
- CPEB sameAs Q5013631.
- CPEB sameAs Q5013631.
- CPEB wasDerivedFrom CPEB?oldid=633171587.
- CPEB isPrimaryTopicOf CPEB.