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- CG_suppression abstract "CG suppression is a term for the phenomenon that CG dinucleotides are very uncommon in most portions of vertebrate genomes. In adult somatic tissues, cytosine residues may be methylated, and this occurs almost exclusively within a symmetric CpG context. Methylated C residues spontaneously deaminate to form T residues; hence CpG dinucleotides steadily mutate to TpG dinucleotides, which gives rise to the under-representation of CpG dinucleotides in the human genome (they occur at only 21% of the expected frequency). (On the other hand, spontaneous deamination of unmethylated C residues gives rise to U residues, a mutation that is quickly recognized and repaired by the cell). In human and mouse, CGs are the least frequent dinucleotide, making up less than 1% of all dinucleotides. GCs are the second most infrequent, making up more than 4% of all dinucleotides, so CGs are more than fourfold less frequent than all other dinucleotides.".
- CG_suppression thumbnail Cytosine_becomes_thymine.png?width=300.
- CG_suppression wikiPageID "13575397".
- CG_suppression wikiPageLength "2014".
- CG_suppression wikiPageOutDegree "9".
- CG_suppression wikiPageRevisionID "659857113".
- CG_suppression wikiPageWikiLink Category:Genomics.
- CG_suppression wikiPageWikiLink CpG_island.
- CG_suppression wikiPageWikiLink CpG_site.
- CG_suppression wikiPageWikiLink DNA_methylation.
- CG_suppression wikiPageWikiLink Dinucleotide.
- CG_suppression wikiPageWikiLink Human.
- CG_suppression wikiPageWikiLink Mouse.
- CG_suppression wikiPageWikiLink Nucleotide.
- CG_suppression wikiPageWikiLink Vertebrate.
- CG_suppression wikiPageWikiLink File:Cytosine_becomes_thymine.png.
- CG_suppression wikiPageWikiLinkText "CG suppression".
- CG_suppression hasPhotoCollection CG_suppression.
- CG_suppression wikiPageUsesTemplate Template:Genetics-stub.
- CG_suppression wikiPageUsesTemplate Template:Reflist.
- CG_suppression subject Category:Genomics.
- CG_suppression hypernym Term.
- CG_suppression type Genomic.
- CG_suppression type Omic.
- CG_suppression comment "CG suppression is a term for the phenomenon that CG dinucleotides are very uncommon in most portions of vertebrate genomes. In adult somatic tissues, cytosine residues may be methylated, and this occurs almost exclusively within a symmetric CpG context.".
- CG_suppression label "CG suppression".
- CG_suppression sameAs m.03c9vlc.
- CG_suppression sameAs Q5011010.
- CG_suppression sameAs Q5011010.
- CG_suppression wasDerivedFrom CG_suppression?oldid=659857113.
- CG_suppression depiction Cytosine_becomes_thymine.png.
- CG_suppression isPrimaryTopicOf CG_suppression.