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- Burantashi abstract "Burantashi (literally "penis get up") is a native Hausa-Fulani powder derived from the bark of the African tree Pausinystalia yohimbe.Burantashi is used as a food additive to barbecued meat (suya) in Nigeria, especially the Northern parts. The extracts contain the alkaloid yohimbine, an alpha-2 antagonist that has been used widely with variable success in erectile dysfunction, but the whole bark of the tree was not studied until recently. In one recent study, pure Burantashi powder obtained from a local suya vendor in Lagos, Nigeria was extracted aqueously and studied on the renal circulation of Sprague-Dawley rats. In the in vivo study, the extract code-named "CCD-X", caused a rise in mean arterial pressure (MAP), and a rise in renal medullary blood flow (MBF). This systemic vasoconstrictor and renal medullary dilator action was attenuated separately by the endothelin -A receptor blocker - BMS-182874, ET-B blocker -BQ788, but blocked by their combination. Further, the nitric oxide inhibitor (NO), L-Nomega - nitro-Arginine Methyl Ester (L-NAME) 10 mg/kg totally inhibited the rise in medullary blood flow due to CCD-X. In vitro studies in isolated perfused kidneys (IPK) and in pressurised microvessels (PMV) confirmed the in vivo effect to cause vasoconstriction, which was inhibited by endothelin A and B antagonists. The pressor dose response characteristic of CCD-X on PMV was similar to that of endothelin-1 with EC50 close to 100 ng. It was concluded from these studies that, the aqueous extract exhibited a vasoconstrictor effect -possibly alpha-2 mediated like yohimbine. However, it possessed additional effects as an andothelin receptor A and B agonist, and also released nitric oxide. The possibility of a post-receptor cross-talk among ET-B, alpha-2 receptors and NO release was also considered. Thin layer chromatography showed that the bark is rich in sesquiterpenes, and has antifungal and antibiotic properties as well. Whether CCD-X will be useful in sickle cell disease (releasing NO) is unknown. Further basic and clinical research are needed before the effects of Burantashi can be effectively evaluated.".
- Burantashi wikiPageExternalLink travels-30-12-2004-001.htm.
- Burantashi wikiPageID "6285712".
- Burantashi wikiPageLength "3060".
- Burantashi wikiPageOutDegree "24".
- Burantashi wikiPageRevisionID "601715743".
- Burantashi wikiPageWikiLink Alkaloid.
- Burantashi wikiPageWikiLink Alpha-2_adrenergic_receptor.
- Burantashi wikiPageWikiLink Antibiotic.
- Burantashi wikiPageWikiLink Antibiotics.
- Burantashi wikiPageWikiLink Antifungal.
- Burantashi wikiPageWikiLink Antifungal_medication.
- Burantashi wikiPageWikiLink Category:Traditional_African_medicine.
- Burantashi wikiPageWikiLink Endothelin.
- Burantashi wikiPageWikiLink Erectile_dysfunction.
- Burantashi wikiPageWikiLink Fula_people.
- Burantashi wikiPageWikiLink Fulani.
- Burantashi wikiPageWikiLink Hausa_people.
- Burantashi wikiPageWikiLink Laboratory_rat.
- Burantashi wikiPageWikiLink Lagos.
- Burantashi wikiPageWikiLink Lagos,_Nigeria.
- Burantashi wikiPageWikiLink Mean_arterial_pressure.
- Burantashi wikiPageWikiLink Nigeria.
- Burantashi wikiPageWikiLink Nitric_oxide.
- Burantashi wikiPageWikiLink Pausinystalia_johimbe.
- Burantashi wikiPageWikiLink Pausinystalia_yohimbe.
- Burantashi wikiPageWikiLink Receptor_antagonist.
- Burantashi wikiPageWikiLink Renal_medulla.
- Burantashi wikiPageWikiLink Sani_Abacha.
- Burantashi wikiPageWikiLink Sesquiterpene.
- Burantashi wikiPageWikiLink Sickle-cell_disease.
- Burantashi wikiPageWikiLink Sickle_cell_disease.
- Burantashi wikiPageWikiLink Sprague-Dawley_rat.
- Burantashi wikiPageWikiLink Thin-layer_chromatography.
- Burantashi wikiPageWikiLink Thin_layer_chromatography.
- Burantashi wikiPageWikiLink Vasoconstriction.
- Burantashi wikiPageWikiLink Vasoconstrictor.
- Burantashi wikiPageWikiLink Yohimbine.
- Burantashi hasPhotoCollection Burantashi.
- Burantashi wikiPageUsesTemplate Template:Multiple_issues.
- Burantashi wikiPageUsesTemplate Template:Reflist.
- Burantashi subject Category:Traditional_African_medicine.
- Burantashi hypernym Powder.
- Burantashi type Article.
- Burantashi type ChemicalCompound.
- Burantashi type Article.
- Burantashi comment "Burantashi (literally "penis get up") is a native Hausa-Fulani powder derived from the bark of the African tree Pausinystalia yohimbe.Burantashi is used as a food additive to barbecued meat (suya) in Nigeria, especially the Northern parts. The extracts contain the alkaloid yohimbine, an alpha-2 antagonist that has been used widely with variable success in erectile dysfunction, but the whole bark of the tree was not studied until recently.".
- Burantashi label "Burantashi".
- Burantashi sameAs m.0f_hhq.
- Burantashi sameAs Q4998119.
- Burantashi sameAs Q4998119.
- Burantashi wasDerivedFrom Burantashi?oldid=601715743.
- Burantashi isPrimaryTopicOf Burantashi.