Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/BU09059> ?p ?o }
Showing triples 1 to 53 of
53
with 100 triples per page.
- BU09059 abstract "BU09059 is a potent and selective, reversible (short-acting) antagonist of the κ-opioid receptor (KOR). It was derived from the irreversible KOR antagonist JDTic in search of an antagonist with a reversible profile of inactivation of the KOR that could be used to treat psychiatric disorders. In addition to its reversibility, BU09059 is much more selective than JDTic, showing 15-fold and 616-fold preference for the KOR over the μ- and δ-opioid receptors (Ki = 1.72 nM, 26.5 nM, and 1060 nM, respectively).".
- BU09059 iupacName "[1-ethoxy-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-1-oxopropan-2-yl] (3R)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide".
- BU09059 thumbnail BU09059_structure.png?width=300.
- BU09059 wikiPageID "46402118".
- BU09059 wikiPageLength "3046".
- BU09059 wikiPageOutDegree "15".
- BU09059 wikiPageRevisionID "656588936".
- BU09059 wikiPageWikiLink ALKS-5461.
- BU09059 wikiPageWikiLink AT-076.
- BU09059 wikiPageWikiLink CERC-501.
- BU09059 wikiPageWikiLink Category:Kappa_antagonists.
- BU09059 wikiPageWikiLink Category:Opioid_antagonists.
- BU09059 wikiPageWikiLink Category:Synthetic_opioids.
- BU09059 wikiPageWikiLink Irreversible_antagonist.
- BU09059 wikiPageWikiLink JDTic.
- BU09059 wikiPageWikiLink Mental_disorder.
- BU09059 wikiPageWikiLink PF-4455242.
- BU09059 wikiPageWikiLink Psychiatric_disorder.
- BU09059 wikiPageWikiLink Receptor_antagonist.
- BU09059 wikiPageWikiLink Reversible_antagonist.
- BU09059 wikiPageWikiLink Δ-opioid_receptor.
- BU09059 wikiPageWikiLink Κ-opioid_receptor.
- BU09059 wikiPageWikiLink Μ-opioid_receptor.
- BU09059 wikiPageWikiLinkText "BU09059".
- BU09059 c "28".
- BU09059 h "37".
- BU09059 hasPhotoCollection BU09059.
- BU09059 iupacName "[1-ethoxy-3-[-4--3,4-dimethylpiperidin-1-yl]-1-oxopropan-2-yl] -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide".
- BU09059 molecularWeight "495.609".
- BU09059 n "3".
- BU09059 o "5".
- BU09059 smiles "Oc3ccccC1CCNCCNCCCc2ccc4O".
- BU09059 wikiPageUsesTemplate Template:Drugbox.
- BU09059 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- BU09059 wikiPageUsesTemplate Template:Opioidergics.
- BU09059 wikiPageUsesTemplate Template:Reflist.
- BU09059 subject Category:Kappa_antagonists.
- BU09059 subject Category:Opioid_antagonists.
- BU09059 subject Category:Synthetic_opioids.
- BU09059 hypernym Antagonist.
- BU09059 type ChemicalSubstance.
- BU09059 type Drug.
- BU09059 type ChemicalObject.
- BU09059 type Thing.
- BU09059 type Q8386.
- BU09059 comment "BU09059 is a potent and selective, reversible (short-acting) antagonist of the κ-opioid receptor (KOR). It was derived from the irreversible KOR antagonist JDTic in search of an antagonist with a reversible profile of inactivation of the KOR that could be used to treat psychiatric disorders.".
- BU09059 label "BU09059".
- BU09059 sameAs m.01347xql.
- BU09059 sameAs Q19903625.
- BU09059 sameAs Q19903625.
- BU09059 wasDerivedFrom BU09059?oldid=656588936.
- BU09059 depiction BU09059_structure.png.
- BU09059 isPrimaryTopicOf BU09059.