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- BD1063 abstract "BD1063 or 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine.In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.".
- BD1063 casNumber "150208-28-9".
- BD1063 iupacName "1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine".
- BD1063 thumbnail BD1063.png?width=300.
- BD1063 wikiPageID "36174254".
- BD1063 wikiPageLength "3292".
- BD1063 wikiPageOutDegree "14".
- BD1063 wikiPageRevisionID "670486859".
- BD1063 wikiPageWikiLink Alcoholism.
- BD1063 wikiPageWikiLink Antagonist.
- BD1063 wikiPageWikiLink BD1008.
- BD1063 wikiPageWikiLink BD1031.
- BD1063 wikiPageWikiLink Binding_affinity.
- BD1063 wikiPageWikiLink Category:Chloroarenes.
- BD1063 wikiPageWikiLink Category:Piperazines.
- BD1063 wikiPageWikiLink LR132.
- BD1063 wikiPageWikiLink Ligand_(biochemistry).
- BD1063 wikiPageWikiLink MDMA.
- BD1063 wikiPageWikiLink Sigma-1_receptor.
- BD1063 wikiPageWikiLink Sigma-2_receptor.
- BD1063 wikiPageWikiLink Sigma_receptor.
- BD1063 wikiPageWikiLinkText "BD1063".
- BD1063 c "13".
- BD1063 casNumber "150208".
- BD1063 chemspiderid "499765".
- BD1063 cl "2".
- BD1063 h "18".
- BD1063 hasPhotoCollection BD1063.
- BD1063 inchi "1".
- BD1063 inchikey "SUIZRDJCBVPASY-UHFFFAOYAY".
- BD1063 iupacName "1".
- BD1063 molecularWeight "273.2".
- BD1063 n "2".
- BD1063 smiles "CN1CCNCCc2cccCl".
- BD1063 stdinchi "1".
- BD1063 stdinchikey "SUIZRDJCBVPASY-UHFFFAOYSA-N".
- BD1063 wikiPageUsesTemplate Template:Drugbox.
- BD1063 wikiPageUsesTemplate Template:Reflist.
- BD1063 subject Category:Chloroarenes.
- BD1063 subject Category:Piperazines.
- BD1063 hypernym Antagonist.
- BD1063 type Article.
- BD1063 type ChemicalSubstance.
- BD1063 type Drug.
- BD1063 type Article.
- BD1063 type Chemical.
- BD1063 type Heterocycle.
- BD1063 type Organohalide.
- BD1063 type Organohalide.
- BD1063 type ChemicalObject.
- BD1063 type Thing.
- BD1063 type Q8386.
- BD1063 comment "BD1063 or 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine.In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.".
- BD1063 label "BD1063".
- BD1063 sameAs m.0ch4vps.
- BD1063 sameAs BD-1063.
- BD1063 sameAs BD-1063.
- BD1063 sameAs Q4835358.
- BD1063 sameAs Q4835358.
- BD1063 wasDerivedFrom BD1063?oldid=670486859.
- BD1063 depiction BD1063.png.
- BD1063 isPrimaryTopicOf BD1063.