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- Autophagin abstract "Autophagin-1 (Atg4/Apg4) is a unique cysteine protease responsible for the cleavage of the carboxyl terminus of Atg8/Apg8/Aut7, a reaction essential for its lipidation during autophagy. Human Atg4 homologues cleave the carboxyl termini of the three human Atg8 homologues, microtubule-associated protein light chain 3 (LC3), GABARAP, and GATE-16.The rapid advancement in our understanding of the mechanisms and regulation of autophagy has placed this process in the center of current research in major human disorders. The future challenge is to develop easy methods to separately manipulate the activity of each of the autophagic pathways. This would allow researchers to further understand their contribution to disease such as cancer, neurodegeneration, infectious disease, muscular disorders and possibly will provide therapeutic tools.".
- Autophagin wikiPageID "10270766".
- Autophagin wikiPageLength "2167".
- Autophagin wikiPageOutDegree "16".
- Autophagin wikiPageRevisionID "641038453".
- Autophagin wikiPageWikiLink Apoptosis.
- Autophagin wikiPageWikiLink Autophagy.
- Autophagin wikiPageWikiLink C-terminus.
- Autophagin wikiPageWikiLink Cancer.
- Autophagin wikiPageWikiLink Carboxyl_terminus.
- Autophagin wikiPageWikiLink Category:Cellular_processes.
- Autophagin wikiPageWikiLink Category:EC_3.4.22.
- Autophagin wikiPageWikiLink Category:Posttranslational_modification.
- Autophagin wikiPageWikiLink Cysteine.
- Autophagin wikiPageWikiLink Homology_(biology).
- Autophagin wikiPageWikiLink Infection.
- Autophagin wikiPageWikiLink Infectious_disease.
- Autophagin wikiPageWikiLink Microtubule.
- Autophagin wikiPageWikiLink Neurodegeneration.
- Autophagin wikiPageWikiLink Protease.
- Autophagin wikiPageWikiLink Ubiquitin.
- Autophagin wikiPageWikiLinkText "Autophagin".
- Autophagin wikiPageWikiLinkText "autophagin".
- Autophagin hasPhotoCollection Autophagin.
- Autophagin wikiPageUsesTemplate Template:Cysteine_proteases.
- Autophagin subject Category:Cellular_processes.
- Autophagin subject Category:EC_3.4.22.
- Autophagin subject Category:Posttranslational_modification.
- Autophagin hypernym Protease.
- Autophagin type Biomolecule.
- Autophagin type Process.
- Autophagin comment "Autophagin-1 (Atg4/Apg4) is a unique cysteine protease responsible for the cleavage of the carboxyl terminus of Atg8/Apg8/Aut7, a reaction essential for its lipidation during autophagy.".
- Autophagin label "Autophagin".
- Autophagin sameAs Autofagina.
- Autophagin sameAs m.02q71r7.
- Autophagin sameAs Q4826891.
- Autophagin sameAs Q4826891.
- Autophagin wasDerivedFrom Autophagin?oldid=641038453.
- Autophagin isPrimaryTopicOf Autophagin.