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- Arginine_repressor_ArgR abstract "In molecular biology, the arginine repressor (ArgR) is a repressor of prokaryotic arginine deiminase pathways.The arginine dihydrolase (AD) pathway is found in many prokaryotes and some primitive eukaryotes, an example of the latter being Giardia lamblia (Giardia intestinalis). The three-enzyme anaerobic pathway breaks down L-arginine to form 1 mol of ATP, carbon dioxide and ammonia. In simpler bacteria, the first enzyme, arginine deiminase, can account for up to 10% of total cell protein.Most prokaryotic arginine deiminase pathways are under the control of a repressor gene, termed ArgR. This is a negative regulator, and will only release the arginine deiminase operon for expression in the presence of arginine. The crystal structure of apo-ArgR from Bacillus stearothermophilus has been determined to 2.5A by means of X-ray crystallography. The protein exists as a hexamer of identical subunits, and is shown to have six DNA-binding domains, clustered around a central oligomeric core when bound to arginine. It predominantly interacts with A.T residues in ARG boxes. This hexameric protein binds DNA at its N terminus to repress arginine biosyntheis or activate arginine catabolism. Some species have several ArgR paralogs. In a neighbour-joining tree, some of these paralogous sequences show long branches and differ significantly from the well-conserved C-terminal region.".
- Arginine_repressor_ArgR symbol "Arg_repressor".
- Arginine_repressor_ArgR symbol "Arg_repressor_C".
- Arginine_repressor_ArgR thumbnail PDB_1xxa_EBI.jpg?width=300.
- Arginine_repressor_ArgR wikiPageID "32115510".
- Arginine_repressor_ArgR wikiPageLength "3964".
- Arginine_repressor_ArgR wikiPageOutDegree "25".
- Arginine_repressor_ArgR wikiPageRevisionID "601848326".
- Arginine_repressor_ArgR wikiPageWikiLink Ammonia.
- Arginine_repressor_ArgR wikiPageWikiLink Arginine.
- Arginine_repressor_ArgR wikiPageWikiLink Arginine_deiminase.
- Arginine_repressor_ArgR wikiPageWikiLink Carbon_dioxide.
- Arginine_repressor_ArgR wikiPageWikiLink Catabolism.
- Arginine_repressor_ArgR wikiPageWikiLink Category:Protein_domains.
- Arginine_repressor_ArgR wikiPageWikiLink Cell_(biology).
- Arginine_repressor_ArgR wikiPageWikiLink Crystal_structure.
- Arginine_repressor_ArgR wikiPageWikiLink Gene_expression.
- Arginine_repressor_ArgR wikiPageWikiLink Giardia_lamblia.
- Arginine_repressor_ArgR wikiPageWikiLink Homology_(biology).
- Arginine_repressor_ArgR wikiPageWikiLink Mole_(unit).
- Arginine_repressor_ArgR wikiPageWikiLink Molecular_binding.
- Arginine_repressor_ArgR wikiPageWikiLink Operon.
- Arginine_repressor_ArgR wikiPageWikiLink Prokaryote.
- Arginine_repressor_ArgR wikiPageWikiLink Prokaryotes.
- Arginine_repressor_ArgR wikiPageWikiLink Prokaryotic.
- Arginine_repressor_ArgR wikiPageWikiLink Protein.
- Arginine_repressor_ArgR wikiPageWikiLink Protein-protein_interaction.
- Arginine_repressor_ArgR wikiPageWikiLink Protein–protein_interaction.
- Arginine_repressor_ArgR wikiPageWikiLink Repressor.
- Arginine_repressor_ArgR wikiPageWikiLink Residue_(chemistry).
- Arginine_repressor_ArgR wikiPageWikiLink Sequence_(biology).
- Arginine_repressor_ArgR wikiPageWikiLink Species.
- Arginine_repressor_ArgR wikiPageWikiLink X-ray_crystallography.
- Arginine_repressor_ArgR caption "c-terminal domain of escherichia coli arginine repressor/ l-arginine complex; pb derivative".
- Arginine_repressor_ArgR hasPhotoCollection Arginine_repressor_ArgR.
- Arginine_repressor_ArgR interpro "IPR020899".
- Arginine_repressor_ArgR name "Arginine repressor, C-terminal domain".
- Arginine_repressor_ArgR name "Arginine repressor, DNA binding domain".
- Arginine_repressor_ArgR pfam "PF01316".
- Arginine_repressor_ArgR pfam "PF02863".
- Arginine_repressor_ArgR scop "1".
- Arginine_repressor_ArgR symbol "Arg_repressor".
- Arginine_repressor_ArgR symbol "Arg_repressor_C".
- Arginine_repressor_ArgR wikiPageUsesTemplate Template:Infobox_protein_family.
- Arginine_repressor_ArgR wikiPageUsesTemplate Template:InterPro_content.
- Arginine_repressor_ArgR wikiPageUsesTemplate Template:Orphan.
- Arginine_repressor_ArgR wikiPageUsesTemplate Template:Reflist.
- Arginine_repressor_ArgR subject Category:Protein_domains.
- Arginine_repressor_ArgR hypernym Repressor.
- Arginine_repressor_ArgR type Article.
- Arginine_repressor_ArgR type Biomolecule.
- Arginine_repressor_ArgR type Protein.
- Arginine_repressor_ArgR type Article.
- Arginine_repressor_ArgR type Chemical.
- Arginine_repressor_ArgR type Domain.
- Arginine_repressor_ArgR type Thing.
- Arginine_repressor_ArgR type Q206229.
- Arginine_repressor_ArgR type Q8054.
- Arginine_repressor_ArgR comment "In molecular biology, the arginine repressor (ArgR) is a repressor of prokaryotic arginine deiminase pathways.The arginine dihydrolase (AD) pathway is found in many prokaryotes and some primitive eukaryotes, an example of the latter being Giardia lamblia (Giardia intestinalis). The three-enzyme anaerobic pathway breaks down L-arginine to form 1 mol of ATP, carbon dioxide and ammonia.".
- Arginine_repressor_ArgR label "Arginine repressor ArgR".
- Arginine_repressor_ArgR sameAs m.0gwz7j0.
- Arginine_repressor_ArgR sameAs Q4789583.
- Arginine_repressor_ArgR sameAs Q4789583.
- Arginine_repressor_ArgR wasDerivedFrom Arginine_repressor_ArgR?oldid=601848326.
- Arginine_repressor_ArgR depiction PDB_1xxa_EBI.jpg.
- Arginine_repressor_ArgR isPrimaryTopicOf Arginine_repressor_ArgR.