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- Archease abstract "In molecular biology, the archease' superfamily of proteins are represented in all three domains of life. Archease genes are generally located adjacent to genes encoding proteins involved in DNA or RNA processing and therefore been predicted to be modulators or chaperones involved in DNA or RNA metabolism. Many of the roles of archeases remain to be established experimentally.The function of one of the archeases from the hyperthermophile Pyrococcus abyssi has been determined. The gene encoding the archease (PAB1946) is located in a bicistronic operon immediately upstream from a second open reading frame (PAB1947), which encodes a tRNA m5C methyltransferase. The methyl transferase catalyses m5C formation at several cytosine's within tRNAs with preference for C49; the specificity of the methyltransferase reaction being increased by the archease. The archease exists in monomeric and oligomeric states, with only the oligomeric forms able to bind the methyltransferase. Binding prevents aggregation and hinders dimerisation of the methyltransferase-tRNA complex.The function of this family of archeases as chaperones is supported by structural analysis of the archease from Methanobacterium thermoautotrophicum, which shows homology to heat shock protein 33, a chaperone protein that inhibits the aggregation of partially denatured proteins.".
- Archease symbol "Archease".
- Archease thumbnail PDB_1jw3_EBI.jpg?width=300.
- Archease wikiPageID "32114968".
- Archease wikiPageLength "3219".
- Archease wikiPageOutDegree "27".
- Archease wikiPageRevisionID "648594271".
- Archease wikiPageWikiLink Binding_(molecular).
- Archease wikiPageWikiLink Biomolecular_structure.
- Archease wikiPageWikiLink Catalysis.
- Archease wikiPageWikiLink Category:Protein_domains.
- Archease wikiPageWikiLink Chaperone_(protein).
- Archease wikiPageWikiLink Chaperone_protein.
- Archease wikiPageWikiLink Cytosine.
- Archease wikiPageWikiLink Domain_(biology).
- Archease wikiPageWikiLink Gene.
- Archease wikiPageWikiLink Genes.
- Archease wikiPageWikiLink Heat_shock_protein.
- Archease wikiPageWikiLink Life.
- Archease wikiPageWikiLink Metabolism.
- Archease wikiPageWikiLink Methyl.
- Archease wikiPageWikiLink Methyl_group.
- Archease wikiPageWikiLink Methyltransferase.
- Archease wikiPageWikiLink Molecular_binding.
- Archease wikiPageWikiLink Multiprotein_complex.
- Archease wikiPageWikiLink Open_reading_frame.
- Archease wikiPageWikiLink Operon.
- Archease wikiPageWikiLink Protein.
- Archease wikiPageWikiLink Protein_aggregation.
- Archease wikiPageWikiLink Protein_complex.
- Archease wikiPageWikiLink Protein_family.
- Archease wikiPageWikiLink Proteins.
- Archease wikiPageWikiLink Secondary_structure.
- Archease wikiPageWikiLink Transferase.
- Archease wikiPageWikiLink Upstream_and_downstream_(DNA).
- Archease caption "solution structure of methanobacterium thermoautotrophicum protein 1598. ontario centre for structural proteomics target mth1598_1_140; northeast structural genomics target tt6".
- Archease hasPhotoCollection Archease.
- Archease interpro "IPR002804".
- Archease name "Archease".
- Archease pfam "PF01951".
- Archease scop "1".
- Archease symbol "Archease".
- Archease wikiPageUsesTemplate Template:Infobox_protein_family.
- Archease wikiPageUsesTemplate Template:InterPro_content.
- Archease wikiPageUsesTemplate Template:Orphan.
- Archease wikiPageUsesTemplate Template:Reflist.
- Archease subject Category:Protein_domains.
- Archease type Biomolecule.
- Archease type Protein.
- Archease type Chemical.
- Archease type Domain.
- Archease type Thing.
- Archease type Q206229.
- Archease type Q8054.
- Archease comment "In molecular biology, the archease' superfamily of proteins are represented in all three domains of life. Archease genes are generally located adjacent to genes encoding proteins involved in DNA or RNA processing and therefore been predicted to be modulators or chaperones involved in DNA or RNA metabolism. Many of the roles of archeases remain to be established experimentally.The function of one of the archeases from the hyperthermophile Pyrococcus abyssi has been determined.".
- Archease label "Archease".
- Archease sameAs m.0gx2pkl.
- Archease sameAs Q4785885.
- Archease sameAs Q4785885.
- Archease wasDerivedFrom Archease?oldid=648594271.
- Archease depiction PDB_1jw3_EBI.jpg.
- Archease isPrimaryTopicOf Archease.