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- Amino_acid_kinase abstract "In molecular biology, the amino acid kinase domain is a protein domain. It is found in protein kinases with various specificities, including the aspartate, glutamate and uridylate kinase families. In prokaryotes and plants the synthesis of the essential amino acids lysine and threonine is predominantly regulated by feed-back inhibition of aspartate kinase (AK) and dihydrodipicolinate synthase (DHPS). In Escherichia coli, thrA, metLM, and lysC encode aspartokinase isozymes that show feedback inhibition by threonine, methionine, and lysine, respectively. The lysine-sensitive isoenzyme of aspartate kinase from spinach leaves has a subunit composition of 4 large and 4 small subunits.In plants although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids. The metabolic regulation of expression of an Arabidopsis thaliana aspartate kinase/homoserine dehydrogenase (AK/HSD) gene, which encodes two linked key enzymes in the biosynthetic pathway of aspartate family amino acids has been studied. The conversion of aspartate into either the storage amino acid asparagine or aspartate family amino acids may be subject to a coordinated, reciprocal metabolic control, and this biochemical branch point is a part of a larger, coordinated regulatory mechanism of nitrogen and carbon storage and utilization.".
- Amino_acid_kinase symbol "AA_kinase".
- Amino_acid_kinase thumbnail PDB_2bty_EBI.jpg?width=300.
- Amino_acid_kinase wikiPageID "32018124".
- Amino_acid_kinase wikiPageLength "3338".
- Amino_acid_kinase wikiPageOutDegree "32".
- Amino_acid_kinase wikiPageRevisionID "607776657".
- Amino_acid_kinase wikiPageWikiLink Amino_acid.
- Amino_acid_kinase wikiPageWikiLink Amino_acids.
- Amino_acid_kinase wikiPageWikiLink Arabidopsis_thaliana.
- Amino_acid_kinase wikiPageWikiLink Asparagine.
- Amino_acid_kinase wikiPageWikiLink Aspartate.
- Amino_acid_kinase wikiPageWikiLink Aspartate_kinase.
- Amino_acid_kinase wikiPageWikiLink Aspartic_acid.
- Amino_acid_kinase wikiPageWikiLink Biochemistry.
- Amino_acid_kinase wikiPageWikiLink Carbon.
- Amino_acid_kinase wikiPageWikiLink Carbon_fixation.
- Amino_acid_kinase wikiPageWikiLink Category:Protein_families.
- Amino_acid_kinase wikiPageWikiLink Dehydrogenase.
- Amino_acid_kinase wikiPageWikiLink Enzyme.
- Amino_acid_kinase wikiPageWikiLink Gene_expression.
- Amino_acid_kinase wikiPageWikiLink Gene_regulation.
- Amino_acid_kinase wikiPageWikiLink Glutamate.
- Amino_acid_kinase wikiPageWikiLink Glutamic_acid.
- Amino_acid_kinase wikiPageWikiLink Isoenzyme.
- Amino_acid_kinase wikiPageWikiLink Isozyme.
- Amino_acid_kinase wikiPageWikiLink Isozymes.
- Amino_acid_kinase wikiPageWikiLink Kinase.
- Amino_acid_kinase wikiPageWikiLink Leaf.
- Amino_acid_kinase wikiPageWikiLink Lysine.
- Amino_acid_kinase wikiPageWikiLink Metabolism.
- Amino_acid_kinase wikiPageWikiLink Nitrogen.
- Amino_acid_kinase wikiPageWikiLink Plant.
- Amino_acid_kinase wikiPageWikiLink Plants.
- Amino_acid_kinase wikiPageWikiLink Prokaryote.
- Amino_acid_kinase wikiPageWikiLink Prokaryotes.
- Amino_acid_kinase wikiPageWikiLink Protein_subunit.
- Amino_acid_kinase wikiPageWikiLink Regulation.
- Amino_acid_kinase wikiPageWikiLink Regulation_of_gene_expression.
- Amino_acid_kinase wikiPageWikiLink Synthase.
- Amino_acid_kinase wikiPageWikiLink Threonine.
- Amino_acid_kinase wikiPageWikiLink Uridine_monophosphate.
- Amino_acid_kinase wikiPageWikiLink Uridylate.
- Amino_acid_kinase caption "acetylglutamate kinase from thermotoga maritima complexed with its inhibitor arginine".
- Amino_acid_kinase hasPhotoCollection Amino_acid_kinase.
- Amino_acid_kinase interpro "IPR001048".
- Amino_acid_kinase name "AA_kinase".
- Amino_acid_kinase pfam "PF00696".
- Amino_acid_kinase prosite "PDOC00289".
- Amino_acid_kinase scop "1".
- Amino_acid_kinase symbol "AA_kinase".
- Amino_acid_kinase wikiPageUsesTemplate Template:Infobox_protein_family.
- Amino_acid_kinase wikiPageUsesTemplate Template:InterPro_content.
- Amino_acid_kinase wikiPageUsesTemplate Template:Orphan.
- Amino_acid_kinase wikiPageUsesTemplate Template:Reflist.
- Amino_acid_kinase subject Category:Protein_families.
- Amino_acid_kinase hypernym Domain.
- Amino_acid_kinase type Biomolecule.
- Amino_acid_kinase type Protein.
- Amino_acid_kinase type Chemical.
- Amino_acid_kinase type Thing.
- Amino_acid_kinase type Q206229.
- Amino_acid_kinase type Q8054.
- Amino_acid_kinase comment "In molecular biology, the amino acid kinase domain is a protein domain. It is found in protein kinases with various specificities, including the aspartate, glutamate and uridylate kinase families. In prokaryotes and plants the synthesis of the essential amino acids lysine and threonine is predominantly regulated by feed-back inhibition of aspartate kinase (AK) and dihydrodipicolinate synthase (DHPS).".
- Amino_acid_kinase label "Amino acid kinase".
- Amino_acid_kinase sameAs m.0gwz1f4.
- Amino_acid_kinase sameAs Q4746430.
- Amino_acid_kinase sameAs Q4746430.
- Amino_acid_kinase wasDerivedFrom Amino_acid_kinase?oldid=607776657.
- Amino_acid_kinase depiction PDB_2bty_EBI.jpg.
- Amino_acid_kinase isPrimaryTopicOf Amino_acid_kinase.