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- Alanine_aminopeptidase abstract "Alanine aminopeptidase (EC 3.4.11.2) is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is found at high levels in the urine when there are kidney problems.Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.".
- Alanine_aminopeptidase entrezgene "290".
- Alanine_aminopeptidase wikiPageExternalLink merops.cgi?id=M01.001.
- Alanine_aminopeptidase wikiPageID "1300765".
- Alanine_aminopeptidase wikiPageLength "8490".
- Alanine_aminopeptidase wikiPageOutDegree "8".
- Alanine_aminopeptidase wikiPageRevisionID "659786240".
- Alanine_aminopeptidase wikiPageWikiLink Biomarker.
- Alanine_aminopeptidase wikiPageWikiLink Category:Biomarkers.
- Alanine_aminopeptidase wikiPageWikiLink Category:EC_3.4.11.
- Alanine_aminopeptidase wikiPageWikiLink Enzyme.
- Alanine_aminopeptidase wikiPageWikiLink Kidney.
- Alanine_aminopeptidase wikiPageWikiLink MEROPS.
- Alanine_aminopeptidase wikiPageWikiLink Nephrology.
- Alanine_aminopeptidase wikiPageWikiLink Urine.
- Alanine_aminopeptidase wikiPageWikiLinkText "AAP".
- Alanine_aminopeptidase wikiPageWikiLinkText "ANPEP".
- Alanine_aminopeptidase wikiPageWikiLinkText "Alanine aminopeptidase".
- Alanine_aminopeptidase wikiPageWikiLinkText "alanine aminopeptidase".
- Alanine_aminopeptidase hasPhotoCollection Alanine_aminopeptidase.
- Alanine_aminopeptidase requireManualInspection "no".
- Alanine_aminopeptidase summaryText "Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.".
- Alanine_aminopeptidase updateCitations "yes".
- Alanine_aminopeptidase updatePage "yes".
- Alanine_aminopeptidase updateProteinBox "yes".
- Alanine_aminopeptidase updateSummary "yes".
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Clusters_of_differentiation.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Clusters_of_differentiation_by_lineage.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:EC_number.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Hydrolase-stub.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:MeshName.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:PBB.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:PBB_Controls.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:PBB_Further_reading.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:PBB_Summary.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Proteases.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Refbegin.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Refend.
- Alanine_aminopeptidase wikiPageUsesTemplate Template:Reflist.
- Alanine_aminopeptidase subject Category:Biomarkers.
- Alanine_aminopeptidase subject Category:EC_3.4.11.
- Alanine_aminopeptidase hypernym Enzyme.
- Alanine_aminopeptidase type Biomolecule.
- Alanine_aminopeptidase type Protein.
- Alanine_aminopeptidase type Sign.
- Alanine_aminopeptidase type Thing.
- Alanine_aminopeptidase type Q206229.
- Alanine_aminopeptidase type Q8054.
- Alanine_aminopeptidase comment "Alanine aminopeptidase (EC 3.4.11.2) is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is found at high levels in the urine when there are kidney problems.Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes.".
- Alanine_aminopeptidase label "Alanine aminopeptidase".
- Alanine_aminopeptidase sameAs إيه_إيه_بي.
- Alanine_aminopeptidase sameAs CD13.
- Alanine_aminopeptidase sameAs Alanine_aminopeptidase.
- Alanine_aminopeptidase sameAs Aminopeptidase_N.
- Alanine_aminopeptidase sameAs m.04r3h_.
- Alanine_aminopeptidase sameAs Аланинаминопептидаза.
- Alanine_aminopeptidase sameAs Alaninska_aminopeptidaza.
- Alanine_aminopeptidase sameAs Alaninska_aminopeptidaza.
- Alanine_aminopeptidase sameAs Q2830638.
- Alanine_aminopeptidase sameAs Q2830638.
- Alanine_aminopeptidase wasDerivedFrom Alanine_aminopeptidase?oldid=659786240.
- Alanine_aminopeptidase isPrimaryTopicOf Alanine_aminopeptidase.