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- Agelasine abstract "Agelasines are 7,9-dialkylpurinium salts isolated from marine sponges (Agelas sp.). They are considered secondary metabolites. Their contribution to the sponge is assumed to be some sort of protection against microorganisms. At the present time a total of eleven 9-methyladeninium salts, agelasine A–I, epiagelasine C and agelin B, are known. All compounds carry a diterpenoid side chain in the adenine 7-position. The agelasines are closely related in structure with the agelasimines.Chemists have reproduced (–)-agelasine A, (–)-agelasine B, (−)-agelasine E, (−)-agelasine F, and (+)-agelasine D by organic synthesis. Agelasines are associated with bioactivities such as antimicrobial and cytotoxic effects, as well as contractive responses of smooth muscles and inhibition of Na/K-ATPase (NaKATPase). Furthermore, in vitro activity against Mycobacterium tuberculosis is reported for agelasine F.".
- Agelasine thumbnail Agelasine_A.svg?width=300.
- Agelasine wikiPageID "2491742".
- Agelasine wikiPageLength "2596".
- Agelasine wikiPageOutDegree "20".
- Agelasine wikiPageRevisionID "646110530".
- Agelasine wikiPageWikiLink Adenine.
- Agelasine wikiPageWikiLink Agelasimine.
- Agelasine wikiPageWikiLink Agelasimines.
- Agelasine wikiPageWikiLink Antimicrobial.
- Agelasine wikiPageWikiLink Category:Alkaloids.
- Agelasine wikiPageWikiLink Category:Diterpenes.
- Agelasine wikiPageWikiLink Category:Purines.
- Agelasine wikiPageWikiLink Category:Quaternary_ammonium_compounds.
- Agelasine wikiPageWikiLink Cytotoxic.
- Agelasine wikiPageWikiLink Cytotoxicity.
- Agelasine wikiPageWikiLink In_vitro.
- Agelasine wikiPageWikiLink Microorganism.
- Agelasine wikiPageWikiLink Mycobacterium_tuberculosis.
- Agelasine wikiPageWikiLink K+-ATPase.
- Agelasine wikiPageWikiLink NaKATPase.
- Agelasine wikiPageWikiLink Organic_synthesis.
- Agelasine wikiPageWikiLink Salt_(chemistry).
- Agelasine wikiPageWikiLink Sea_sponge.
- Agelasine wikiPageWikiLink Secondary_metabolite.
- Agelasine wikiPageWikiLink Side_chain.
- Agelasine wikiPageWikiLink Smooth_muscle_tissue.
- Agelasine wikiPageWikiLink Smooth_muscles.
- Agelasine wikiPageWikiLink Sponge.
- Agelasine wikiPageWikiLink Terpenoid.
- Agelasine wikiPageWikiLink File:Agelasine_A.svg.
- Agelasine wikiPageWikiLinkText "Agelasine".
- Agelasine wikiPageWikiLinkText "agelasine".
- Agelasine hasPhotoCollection Agelasine.
- Agelasine wikiPageUsesTemplate Template:Reflist.
- Agelasine subject Category:Alkaloids.
- Agelasine subject Category:Diterpenes.
- Agelasine subject Category:Purines.
- Agelasine subject Category:Quaternary_ammonium_compounds.
- Agelasine hypernym Salts.
- Agelasine type Biomolecule.
- Agelasine type ChemicalCompound.
- Agelasine type Alkaloid.
- Agelasine type Biomolecule.
- Agelasine type Diterpene.
- Agelasine type Heterocycle.
- Agelasine type Terpene.
- Agelasine comment "Agelasines are 7,9-dialkylpurinium salts isolated from marine sponges (Agelas sp.). They are considered secondary metabolites. Their contribution to the sponge is assumed to be some sort of protection against microorganisms. At the present time a total of eleven 9-methyladeninium salts, agelasine A–I, epiagelasine C and agelin B, are known. All compounds carry a diterpenoid side chain in the adenine 7-position.".
- Agelasine label "Agelasine".
- Agelasine sameAs Agelasina.
- Agelasine sameAs m.07hmfw.
- Agelasine sameAs Q4691963.
- Agelasine sameAs Q4691963.
- Agelasine wasDerivedFrom Agelasine?oldid=646110530.
- Agelasine depiction Agelasine_A.svg.
- Agelasine isPrimaryTopicOf Agelasine.