Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Actin> ?p ?o }
- Actin abstract "Actin is a globular multi-functional protein that forms microfilaments. It is found in essentially all eukaryotic cells (the only known exception being nematode sperm), where it may be present at concentrations of over 100 μM. An actin protein's mass is roughly 42-kDa and it is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division.Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Many of these processes are mediated by extensive and intimate interactions of actin with cellular membranes. In vertebrates, three main groups of actin isoforms, alpha, beta, and gamma have been identified. The alpha actins, found in muscle tissues, are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. It is believed that the diverse range of structures formed by actin enabling it to fulfill such a large range of functions is regulated through the binding of tropomyosin along the filaments.A cell’s ability to dynamically form microfilaments provides the scaffolding that allows it to rapidly remodel itself in response to its environment or to the organism’s internal signals, for example, to increase cell membrane absorption or increase cell adhesion in order to form cell tissue. Other enzymes or organelles such as cilia can be anchored to this scaffolding in order to control the deformation of the external cell membrane, which allows endocytosis and cytokinesis. It can also produce movement either by itself or with the help of molecular motors. Actin therefore contributes to processes such as the intracellular transport of vesicles and organelles as well as muscular contraction and cellular migration. It therefore plays an important role in embryogenesis, the healing of wounds and the invasivity of cancer cells. The evolutionary origin of actin can be traced to prokaryotic cells, which have equivalent proteins. Actin homologs from prokaryotes and archea polymerize into different helical or linear filaments consisting of one or multiple strands. However the in-strand contacts and nucleotide binding sites are preserved in prokaryotes and in archea. Lastly, actin plays an important role in the control of gene expression.A large number of illnesses and diseases are caused by mutations in alleles of the genes that regulate the production of actin or of its associated proteins. The production of actin is also key to the process of infection by some pathogenic microorganisms. Mutations in the different genes that regulate actin production in humans can cause muscular diseases, variations in the size and function of the heart as well as deafness. The make-up of the cytoskeleton is also related to the pathogenicity of intracellular bacteria and viruses, particularly in the processes related to evading the actions of the immune system.".
- Actin symbol "Actin".
- Actin thumbnail Actin_with_ADP_highlighted.png?width=300.
- Actin wikiPageExternalLink actin-staining-techniques.
- Actin wikiPageExternalLink go-0003779.
- Actin wikiPageExternalLink 1_go-0030041.
- Actin wikiPageExternalLink go-0045010.
- Actin wikiPageExternalLink actin*.
- Actin wikiPageID "438944".
- Actin wikiPageLength "140898".
- Actin wikiPageOutDegree "674".
- Actin wikiPageRevisionID "680975072".
- Actin wikiPageWikiLink 3_UTR.
- Actin wikiPageWikiLink 5_UTR.
- Actin wikiPageWikiLink ACTA1.
- Actin wikiPageWikiLink ACTA2.
- Actin wikiPageWikiLink ACTB.
- Actin wikiPageWikiLink ACTC1.
- Actin wikiPageWikiLink ACTG1.
- Actin wikiPageWikiLink ACTG2.
- Actin wikiPageWikiLink ATPase.
- Actin wikiPageWikiLink Acetyl.
- Actin wikiPageWikiLink Acid.
- Actin wikiPageWikiLink Actin,_alpha_1.
- Actin wikiPageWikiLink Actin-binding_protein.
- Actin wikiPageWikiLink Actin_remodeling.
- Actin wikiPageWikiLink Actinin.
- Actin wikiPageWikiLink Action_potential.
- Actin wikiPageWikiLink Active_matter.
- Actin wikiPageWikiLink Active_site.
- Actin wikiPageWikiLink Adenosine_diphosphate.
- Actin wikiPageWikiLink Adenosine_triphosphate.
- Actin wikiPageWikiLink Adenylate_cyclase.
- Actin wikiPageWikiLink Albert_Szent-Györgyi.
- Actin wikiPageWikiLink Algae.
- Actin wikiPageWikiLink Alkaloid.
- Actin wikiPageWikiLink Allele.
- Actin wikiPageWikiLink Alpha_catenin.
- Actin wikiPageWikiLink Alternation_of_generations.
- Actin wikiPageWikiLink Alternative_splicing.
- Actin wikiPageWikiLink Amanita_phalloides.
- Actin wikiPageWikiLink Amino_acid.
- Actin wikiPageWikiLink Amino_acid_sequence.
- Actin wikiPageWikiLink Amoeba.
- Actin wikiPageWikiLink Amyloidosis.
- Actin wikiPageWikiLink Anastomosis.
- Actin wikiPageWikiLink Angstrom.
- Actin wikiPageWikiLink Animal.
- Actin wikiPageWikiLink Animal_cell.
- Actin wikiPageWikiLink Antibacterial.
- Actin wikiPageWikiLink Antibiotics.
- Actin wikiPageWikiLink Aorta.
- Actin wikiPageWikiLink Aortic_aneurism.
- Actin wikiPageWikiLink Aortic_aneurysm.
- Actin wikiPageWikiLink Apoptosis.
- Actin wikiPageWikiLink Arabidopsis_thaliana.
- Actin wikiPageWikiLink Archaea.
- Actin wikiPageWikiLink Arginine.
- Actin wikiPageWikiLink 3.
- Actin wikiPageWikiLink 3_complex.
- Actin wikiPageWikiLink Aspartic_acid.
- Actin wikiPageWikiLink Atomic_mass_unit.
- Actin wikiPageWikiLink Atrium_(heart).
- Actin wikiPageWikiLink Atrophy.
- Actin wikiPageWikiLink Axon.
- Actin wikiPageWikiLink Bacteria.
- Actin wikiPageWikiLink Base_(chemistry).
- Actin wikiPageWikiLink Beta-actin.
- Actin wikiPageWikiLink Beta-catenin.
- Actin wikiPageWikiLink Beta_hairpin.
- Actin wikiPageWikiLink Beta_sheet.
- Actin wikiPageWikiLink Biochemical.
- Actin wikiPageWikiLink Biochemistry.
- Actin wikiPageWikiLink Biofilm.
- Actin wikiPageWikiLink Biomolecular_structure.
- Actin wikiPageWikiLink Biopolymer.
- Actin wikiPageWikiLink Biopsy.
- Actin wikiPageWikiLink Brownian_motion.
- Actin wikiPageWikiLink Brunó_Ferenc_Straub.
- Actin wikiPageWikiLink Burkholderia_pseudomallei.
- Actin wikiPageWikiLink C-terminus.
- Actin wikiPageWikiLink CAP_(protein).
- Actin wikiPageWikiLink Cadherin.
- Actin wikiPageWikiLink Calcium.
- Actin wikiPageWikiLink Calcium_in_biology.
- Actin wikiPageWikiLink Calmodulin.
- Actin wikiPageWikiLink Calpain.
- Actin wikiPageWikiLink Cancer.
- Actin wikiPageWikiLink Candida_albicans.
- Actin wikiPageWikiLink CapZ.
- Actin wikiPageWikiLink Cardiac_muscle.
- Actin wikiPageWikiLink Catalysis.
- Actin wikiPageWikiLink Category:Articles_containing_video_clips.
- Actin wikiPageWikiLink Category:Autoantigens.
- Actin wikiPageWikiLink Category:Cytoskeleton.
- Actin wikiPageWikiLink Category:Structural_proteins.
- Actin wikiPageWikiLink Catenin.
- Actin wikiPageWikiLink Cation.
- Actin wikiPageWikiLink Cell_(biology).
- Actin wikiPageWikiLink Cell_adhesion.