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- ANTH_domain abstract "The ANTH domain is a membrane binding domain that shows weak specificity for PtdIns(4,5)P2. It was found in AP180 (a.k.a. CALM) endocytotic accessory protein that has been implicated in the formation of clathrin-coated pits. The domain is involved in phosphatidylinositol 4,5-bisphosphate binding and is a universal adaptor for nucleation of clathrin coats.Its structure is a solenoid of 9 helices. The PtdIns(4,5)P2 binding residues are spread over several helices at the tip of the structure. The PtdIns(4,5)P2 binding sequence is Kx9Kx(K/R)(H/Y).An ANTH domain is also found in HIP1 and HIP1R, and the PtdIns(4,5)P2 binding sequence is conserved. More information is found on endocytosis.org.".
- ANTH_domain symbol "ANTH".
- ANTH_domain thumbnail 1hfa_opm.png?width=300.
- ANTH_domain wikiPageExternalLink AP180.html.
- ANTH_domain wikiPageID "6910971".
- ANTH_domain wikiPageLength "2534".
- ANTH_domain wikiPageOutDegree "11".
- ANTH_domain wikiPageRevisionID "659775998".
- ANTH_domain wikiPageWikiLink AP180.
- ANTH_domain wikiPageWikiLink Ap180.
- ANTH_domain wikiPageWikiLink Category:Peripheral_membrane_proteins.
- ANTH_domain wikiPageWikiLink Category:Protein_domains.
- ANTH_domain wikiPageWikiLink HIP1.
- ANTH_domain wikiPageWikiLink HIP1R.
- ANTH_domain wikiPageWikiLink Huntingtin-interacting_protein_1.
- ANTH_domain wikiPageWikiLink PICALM.
- ANTH_domain wikiPageWikiLink Phosphatidylinositol_4,5-bisphosphate.
- ANTH_domain wikiPageWikiLink PtdIns(4,5)P2.
- ANTH_domain wikiPageWikiLink SNAP91.
- ANTH_domain wikiPageWikiLinkText "ANTH domain".
- ANTH_domain caption "Clathrin assembly lymphoid myeloid leukemia protein".
- ANTH_domain cdd "cd03564".
- ANTH_domain hasPhotoCollection ANTH_domain.
- ANTH_domain interpro "IPR011417".
- ANTH_domain name "ANTH domain".
- ANTH_domain opmFamily "39".
- ANTH_domain opmProtein "1".
- ANTH_domain pdb "A:21-299 A:19-285 A:19-285 A:19-285 A:19-285".
- ANTH_domain pfam "PF07651".
- ANTH_domain symbol "ANTH".
- ANTH_domain wikiPageUsesTemplate Template:Cite_journal.
- ANTH_domain wikiPageUsesTemplate Template:Pfam_box.
- ANTH_domain wikiPageUsesTemplate Template:Reflist.
- ANTH_domain wikiPageUsesTemplate Template:UMichOPM.
- ANTH_domain subject Category:Peripheral_membrane_proteins.
- ANTH_domain subject Category:Protein_domains.
- ANTH_domain hypernym Domain.
- ANTH_domain type Biomolecule.
- ANTH_domain type Protein.
- ANTH_domain type Chemical.
- ANTH_domain type Domain.
- ANTH_domain type Thing.
- ANTH_domain type Q206229.
- ANTH_domain type Q8054.
- ANTH_domain comment "The ANTH domain is a membrane binding domain that shows weak specificity for PtdIns(4,5)P2. It was found in AP180 (a.k.a. CALM) endocytotic accessory protein that has been implicated in the formation of clathrin-coated pits. The domain is involved in phosphatidylinositol 4,5-bisphosphate binding and is a universal adaptor for nucleation of clathrin coats.Its structure is a solenoid of 9 helices. The PtdIns(4,5)P2 binding residues are spread over several helices at the tip of the structure.".
- ANTH_domain label "ANTH domain".
- ANTH_domain sameAs m.0gwmls.
- ANTH_domain sameAs Q4653058.
- ANTH_domain sameAs Q4653058.
- ANTH_domain wasDerivedFrom ANTH_domain?oldid=659775998.
- ANTH_domain depiction 1hfa_opm.png.
- ANTH_domain isPrimaryTopicOf ANTH_domain.