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- ALAD abstract "Delta-aminolevulinic acid dehydratase is an enzyme that in humans is encoded by the ALAD gene.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.".
- ALAD entrezgene "210".
- ALAD wikiPageID "14167645".
- ALAD wikiPageLength "7510".
- ALAD wikiPageOutDegree "3".
- ALAD wikiPageRevisionID "659775047".
- ALAD wikiPageWikiLink Enzyme.
- ALAD wikiPageWikiLink Gene.
- ALAD wikiPageWikiLink Robert_J._Desnick.
- ALAD wikiPageWikiLinkText "ALAD".
- ALAD wikiPageWikiLinkText "Delta-aminolevulinic acid dehydratase".
- ALAD hasPhotoCollection ALAD.
- ALAD requireManualInspection "no".
- ALAD summaryText "The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen . ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.".
- ALAD updateCitations "yes".
- ALAD updatePage "yes".
- ALAD updateProteinBox "yes".
- ALAD updateSummary "yes".
- ALAD wikiPageUsesTemplate Template:Gene-9-stub.
- ALAD wikiPageUsesTemplate Template:PBB.
- ALAD wikiPageUsesTemplate Template:PBB_Controls.
- ALAD wikiPageUsesTemplate Template:PBB_Further_reading.
- ALAD wikiPageUsesTemplate Template:PBB_Summary.
- ALAD wikiPageUsesTemplate Template:PDB_Gallery.
- ALAD wikiPageUsesTemplate Template:Refbegin.
- ALAD wikiPageUsesTemplate Template:Refend.
- ALAD wikiPageUsesTemplate Template:Reflist.
- ALAD hypernym Enzyme.
- ALAD type Biomolecule.
- ALAD type Protein.
- ALAD type Thing.
- ALAD type Q206229.
- ALAD type Q8054.
- ALAD comment "Delta-aminolevulinic acid dehydratase is an enzyme that in humans is encoded by the ALAD gene.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity.".
- ALAD label "ALAD".
- ALAD sameAs 5-amminolevulinato_deidratasi.
- ALAD sameAs m.03cwnzl.
- ALAD sameAs Q3599226.
- ALAD sameAs Q3599226.
- ALAD wasDerivedFrom ALAD?oldid=659775047.
- ALAD isPrimaryTopicOf ALAD.