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- ACT_Biotech_Inc abstract "ACT Biotech Inc is a San Francisco-based, privately held biopharmaceutical company focused on the development and commercialization of targeted cancer drugs.The Company's clinical stage pipeline includes :Telatinib, an oral kinase inhibitor for the first-line treatment of advanced gastric cancer. It has been granted Orphan Drug status by the U.S. Food and Drug Administration (FDA). It has reported encouraging interim results from a phase II trial.ACTB1003, an oral kinase inhibitor that targets cancer cells through multiple modes of action. It inhibits cancer cell growth by targeting the FGF receptor family, which are mutated in a number of human cancer types. ACTB1003 also directly induces apoptosis by targeting kinases downstream of the PI3K pathway, all at low nanomolar concentrations.Other pipeline products include an oral Aurora A and B kinase inhibitor at the pre-IND stage, and an ABL tyrosine kinase inhibitor targeting the T315I mutant enzyme in pre-clinical development.".
- ACT_Biotech_Inc wikiPageExternalLink www.actbiotech.com.
- ACT_Biotech_Inc wikiPageID "29254986".
- ACT_Biotech_Inc wikiPageLength "2266".
- ACT_Biotech_Inc wikiPageOutDegree "18".
- ACT_Biotech_Inc wikiPageRevisionID "506298053".
- ACT_Biotech_Inc wikiPageWikiLink ABL_(gene).
- ACT_Biotech_Inc wikiPageWikiLink ACTB1003.
- ACT_Biotech_Inc wikiPageWikiLink Abl_gene.
- ACT_Biotech_Inc wikiPageWikiLink Apoptosis.
- ACT_Biotech_Inc wikiPageWikiLink Aurora_A.
- ACT_Biotech_Inc wikiPageWikiLink Aurora_A_kinase.
- ACT_Biotech_Inc wikiPageWikiLink Aurora_B.
- ACT_Biotech_Inc wikiPageWikiLink Aurora_B_kinase.
- ACT_Biotech_Inc wikiPageWikiLink Aurora_inhibitor.
- ACT_Biotech_Inc wikiPageWikiLink Category:Biotechnology_companies_of_the_United_States.
- ACT_Biotech_Inc wikiPageWikiLink Category:Pharmaceutical_companies_of_the_United_States.
- ACT_Biotech_Inc wikiPageWikiLink Fibroblast_growth_factor_receptor.
- ACT_Biotech_Inc wikiPageWikiLink Food_and_Drug_Administration.
- ACT_Biotech_Inc wikiPageWikiLink Gastric_cancer.
- ACT_Biotech_Inc wikiPageWikiLink Kinase_inhibitor.
- ACT_Biotech_Inc wikiPageWikiLink Orphan_Drug.
- ACT_Biotech_Inc wikiPageWikiLink Orphan_drug.
- ACT_Biotech_Inc wikiPageWikiLink mTOR_pathway.
- ACT_Biotech_Inc wikiPageWikiLink Protein_kinase_inhibitor.
- ACT_Biotech_Inc wikiPageWikiLink Stomach_cancer.
- ACT_Biotech_Inc wikiPageWikiLink T315I.
- ACT_Biotech_Inc wikiPageWikiLink Targeted_therapy.
- ACT_Biotech_Inc wikiPageWikiLink Telatinib.
- ACT_Biotech_Inc wikiPageWikiLink Tyrosine-kinase_inhibitor.
- ACT_Biotech_Inc wikiPageWikiLink Tyrosine_kinase_inhibitor.
- ACT_Biotech_Inc wikiPageWikiLinkText "ACT Biotech Inc".
- ACT_Biotech_Inc hasPhotoCollection ACT_Biotech_Inc.
- ACT_Biotech_Inc wikiPageUsesTemplate Template:Reflist.
- ACT_Biotech_Inc subject Category:Biotechnology_companies_of_the_United_States.
- ACT_Biotech_Inc subject Category:Pharmaceutical_companies_of_the_United_States.
- ACT_Biotech_Inc type Company.
- ACT_Biotech_Inc type Company.
- ACT_Biotech_Inc comment "ACT Biotech Inc is a San Francisco-based, privately held biopharmaceutical company focused on the development and commercialization of targeted cancer drugs.The Company's clinical stage pipeline includes :Telatinib, an oral kinase inhibitor for the first-line treatment of advanced gastric cancer. It has been granted Orphan Drug status by the U.S. Food and Drug Administration (FDA).".
- ACT_Biotech_Inc label "ACT Biotech Inc".
- ACT_Biotech_Inc sameAs m.0dln6n3.
- ACT_Biotech_Inc sameAs Q4650874.
- ACT_Biotech_Inc sameAs Q4650874.
- ACT_Biotech_Inc wasDerivedFrom ACT_Biotech_Inc?oldid=506298053.
- ACT_Biotech_Inc isPrimaryTopicOf ACT_Biotech_Inc.