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- A-796,260 abstract "A-796,260 is a drug developed by Abbott Laboratories that acts as a potent and selective cannabinoid CB2 receptor agonist. Replacing the aromatic 3-benzoyl or 3-naphthoyl group found in most indole derived cannabinoids with the 3-tetramethylcyclopropylmethanone group, imparts significant selectivity for CB2, and A-796,260 was found to be a highly selective CB2 agonist with little affinity for CB1, having a CB2 Ki of 4.6 nM vs 945 nM at CB1. It has potent analgesic and anti-inflammatory actions in animal models, being especially effective in models of neuropathic pain, but without producing cannabis-like behavioral effects.".
- A-796,260 casNumber "895155-26-7".
- A-796,260 iupacName "[1-(2-morpholin-4-ylethyl)-1H-indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone".
- A-796,260 pubchem "11584525".
- A-796,260 thumbnail A-796260_structure.png?width=300.
- A-796,260 wikiPageID "30411492".
- A-796,260 wikiPageLength "3304".
- A-796,260 wikiPageOutDegree "24".
- A-796,260 wikiPageRevisionID "683539103".
- A-796,260 wikiPageWikiLink A-834,735.
- A-796,260 wikiPageWikiLink A-836,339.
- A-796,260 wikiPageWikiLink Abbott_Laboratories.
- A-796,260 wikiPageWikiLink Acyl.
- A-796,260 wikiPageWikiLink Agonist.
- A-796,260 wikiPageWikiLink Analgesic.
- A-796,260 wikiPageWikiLink Anti-inflammatory.
- A-796,260 wikiPageWikiLink Benzoyl.
- A-796,260 wikiPageWikiLink Cannabinoid.
- A-796,260 wikiPageWikiLink Cannabinoid_receptor_2.
- A-796,260 wikiPageWikiLink Cannabinoid_receptor_type_2.
- A-796,260 wikiPageWikiLink Category:Aminoalkylindoles.
- A-796,260 wikiPageWikiLink Category:Cannabinoids.
- A-796,260 wikiPageWikiLink Category:Cyclopropanes.
- A-796,260 wikiPageWikiLink Category:Tetramethylcyclopropanoylindoles.
- A-796,260 wikiPageWikiLink Cyclopropanation.
- A-796,260 wikiPageWikiLink Cyclopropyl.
- A-796,260 wikiPageWikiLink Dissociation_constant.
- A-796,260 wikiPageWikiLink Indole.
- A-796,260 wikiPageWikiLink JWH-200.
- A-796,260 wikiPageWikiLink Methanone.
- A-796,260 wikiPageWikiLink Methyl.
- A-796,260 wikiPageWikiLink Methyl_group.
- A-796,260 wikiPageWikiLink Naphthalene.
- A-796,260 wikiPageWikiLink Naphthoyl.
- A-796,260 wikiPageWikiLink Neuropathic_pain.
- A-796,260 wikiPageWikiLink Receptor_(biochemistry).
- A-796,260 wikiPageWikiLink UR-144.
- A-796,260 wikiPageWikiLink XLR-11_(drug).
- A-796,260 wikiPageWikiLinkText "A-796,260".
- A-796,260 c "22".
- A-796,260 casNumber "895155".
- A-796,260 chembl "262865".
- A-796,260 chemspiderid "9759290".
- A-796,260 h "30".
- A-796,260 hasPhotoCollection A-796,260.
- A-796,260 iupacName "[1--1H-indol-3-yl]-methanone".
- A-796,260 molecularWeight "354.485".
- A-796,260 n "2".
- A-796,260 o "2".
- A-796,260 pubchem "11584525".
- A-796,260 smiles "C4COCCN4CCncc1CC2CC2C".
- A-796,260 stdinchi "1".
- A-796,260 stdinchikey "ZCFHOMLAFTWDFM-UHFFFAOYSA-N".
- A-796,260 verifiedfields "changed".
- A-796,260 verifiedrevid "456505609".
- A-796,260 width "200".
- A-796,260 wikiPageUsesTemplate Template:Cannabinoid-stub.
- A-796,260 wikiPageUsesTemplate Template:Cannabinoids.
- A-796,260 wikiPageUsesTemplate Template:Drugbox.
- A-796,260 wikiPageUsesTemplate Template:Reflist.
- A-796,260 subject Category:Aminoalkylindoles.
- A-796,260 subject Category:Cannabinoids.
- A-796,260 subject Category:Cyclopropanes.
- A-796,260 subject Category:Tetramethylcyclopropanoylindoles.
- A-796,260 hypernym Drug.
- A-796,260 type ChemicalSubstance.
- A-796,260 type Drug.
- A-796,260 type ChemicalObject.
- A-796,260 type Thing.
- A-796,260 type Q8386.
- A-796,260 comment "A-796,260 is a drug developed by Abbott Laboratories that acts as a potent and selective cannabinoid CB2 receptor agonist. Replacing the aromatic 3-benzoyl or 3-naphthoyl group found in most indole derived cannabinoids with the 3-tetramethylcyclopropylmethanone group, imparts significant selectivity for CB2, and A-796,260 was found to be a highly selective CB2 agonist with little affinity for CB1, having a CB2 Ki of 4.6 nM vs 945 nM at CB1.".
- A-796,260 label "A-796,260".
- A-796,260 sameAs m.0g5qc0r.
- A-796,260 sameAs A-796,260.
- A-796,260 sameAs A-796,260.
- A-796,260 sameAs Q4646876.
- A-796,260 sameAs Q4646876.
- A-796,260 wasDerivedFrom A-796,260?oldid=683539103.
- A-796,260 depiction A-796260_structure.png.
- A-796,260 isPrimaryTopicOf A-796,260.