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- A-77636 abstract "A-77636 is a synthetic drug which acts as a selective D1 receptor full agonist. It has nootropic, anorectic, rewarding and antiparkinsonian effects in animal studies, but its high potency and long duration of action causes D1 receptor downregulation and tachyphylaxis, and unlike other D1 full agonists such as SKF-82,958, it does not produce place preference in animals. A-77636 partially substituted for cocaine in animal studies, and has been suggested for use as a possible substitute drug in treating addiction, but it is better known for its use in studying the role of D1 receptors in the brain.".
- A-77636 iupacName "(1R,3S)-3-(1-Adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol".
- A-77636 thumbnail A-77636.svg?width=300.
- A-77636 wikiPageID "23696223".
- A-77636 wikiPageLength "7681".
- A-77636 wikiPageOutDegree "16".
- A-77636 wikiPageRevisionID "646838766".
- A-77636 wikiPageWikiLink Agonist.
- A-77636 wikiPageWikiLink Anorectic.
- A-77636 wikiPageWikiLink Antiparkinson.
- A-77636 wikiPageWikiLink Antiparkinsonian.
- A-77636 wikiPageWikiLink Binding_selectivity.
- A-77636 wikiPageWikiLink Category:Adamantanes.
- A-77636 wikiPageWikiLink Category:Catechols.
- A-77636 wikiPageWikiLink Category:Dopamine_agonists.
- A-77636 wikiPageWikiLink Category:Isochromenes.
- A-77636 wikiPageWikiLink Chemical_synthesis.
- A-77636 wikiPageWikiLink Cocaine.
- A-77636 wikiPageWikiLink D1_receptor.
- A-77636 wikiPageWikiLink Dopamine_receptor_D1.
- A-77636 wikiPageWikiLink Drug.
- A-77636 wikiPageWikiLink Full_agonist.
- A-77636 wikiPageWikiLink Hydrochloride.
- A-77636 wikiPageWikiLink Nootropic.
- A-77636 wikiPageWikiLink SKF-82,958.
- A-77636 wikiPageWikiLink Tachyphylaxis.
- A-77636 wikiPageWikiLinkText "A-77636".
- A-77636 hasPhotoCollection A-77636.
- A-77636 imagefile "A-77636.svg".
- A-77636 imagename "Stereo, Kekulé skeletal formula of A-77636".
- A-77636 iupacname "-3".
- A-77636 verifiedfields "changed".
- A-77636 verifiedrevid "477363088".
- A-77636 wikiPageUsesTemplate Template:Anorectics.
- A-77636 wikiPageUsesTemplate Template:Chembox.
- A-77636 wikiPageUsesTemplate Template:Dopaminergics.
- A-77636 wikiPageUsesTemplate Template:Gastrointestinal-drug-stub.
- A-77636 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- A-77636 wikiPageUsesTemplate Template:Nootropics.
- A-77636 wikiPageUsesTemplate Template:Organic-compound-stub.
- A-77636 wikiPageUsesTemplate Template:Reflist.
- A-77636 wikiPageUsesTemplate Template:Stimulants.
- A-77636 subject Category:Adamantanes.
- A-77636 subject Category:Catechols.
- A-77636 subject Category:Dopamine_agonists.
- A-77636 subject Category:Isochromenes.
- A-77636 hypernym Drug.
- A-77636 type Agent.
- A-77636 type ChemicalCompound.
- A-77636 type ChemicalSubstance.
- A-77636 type Drug.
- A-77636 type Agent.
- A-77636 type Agonist.
- A-77636 type Benzenediol.
- A-77636 type Catechol.
- A-77636 type Chemical.
- A-77636 type Drug.
- A-77636 type Heterocycle.
- A-77636 type Hydrocarbon.
- A-77636 type ChemicalObject.
- A-77636 type Thing.
- A-77636 type Q11173.
- A-77636 comment "A-77636 is a synthetic drug which acts as a selective D1 receptor full agonist. It has nootropic, anorectic, rewarding and antiparkinsonian effects in animal studies, but its high potency and long duration of action causes D1 receptor downregulation and tachyphylaxis, and unlike other D1 full agonists such as SKF-82,958, it does not produce place preference in animals.".
- A-77636 label "A-77636".
- A-77636 sameAs A-77636.
- A-77636 sameAs m.06zpkn0.
- A-77636 sameAs A-77636.
- A-77636 sameAs A-77636.
- A-77636 sameAs Q4646883.
- A-77636 sameAs Q4646883.
- A-77636 wasDerivedFrom A-77636?oldid=646838766.
- A-77636 depiction A-77636.svg.
- A-77636 isPrimaryTopicOf A-77636.