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- 3H_domain abstract "In molecular biology, the 3H domain is a protein domain named after its three highly conserved histidine residues. The 3H domain appears to be a small molecule-binding domain, based on its occurrence with other domains. Several proteins carrying this domain are transcriptional regulators from the biotin repressor family. The transcription regulator TM1602 from Thermotoga maritima is a DNA-binding protein thought to belong to a family of de novo NAD synthesis pathway regulators. TM1602 has an N-terminal DNA-binding domain and a C-terminal 3H regulatory domain. The N-terminal domain appears to bind to the NAD promoter region and repress the de novo NAD biosynthesis operon, while the C-terminal 3H domain may bind to nicotinamide, nicotinic acid, or other substrate/products. The 3H domain has a 2-layer alpha/beta sandwich fold.".
- 3H_domain symbol "3H".
- 3H_domain thumbnail PDB_1j5y_EBI.jpg?width=300.
- 3H_domain wikiPageID "31732429".
- 3H_domain wikiPageLength "2551".
- 3H_domain wikiPageOutDegree "15".
- 3H_domain wikiPageRevisionID "589766224".
- 3H_domain wikiPageWikiLink Biosynthesis.
- 3H_domain wikiPageWikiLink Category:Protein_families.
- 3H_domain wikiPageWikiLink Conservation_(genetics).
- 3H_domain wikiPageWikiLink Conserved_sequence.
- 3H_domain wikiPageWikiLink Domain_(biology).
- 3H_domain wikiPageWikiLink Gene_regulation.
- 3H_domain wikiPageWikiLink Histidine.
- 3H_domain wikiPageWikiLink Nicotinamide.
- 3H_domain wikiPageWikiLink Promoter_(genetics).
- 3H_domain wikiPageWikiLink Promotor_(biology).
- 3H_domain wikiPageWikiLink Protein.
- 3H_domain wikiPageWikiLink Protein_domain.
- 3H_domain wikiPageWikiLink Protein_family.
- 3H_domain wikiPageWikiLink Protein_folding.
- 3H_domain wikiPageWikiLink Proteins.
- 3H_domain wikiPageWikiLink Regulation_of_gene_expression.
- 3H_domain wikiPageWikiLink Repressor.
- 3H_domain wikiPageWikiLink Transcription_(genetics).
- 3H_domain wikiPageWikiLink Transcriptional_regulation.
- 3H_domain caption "crystal structure of transcriptional regulator from thermotoga maritima at 2.3 a resolution".
- 3H_domain hasPhotoCollection 3H_domain.
- 3H_domain interpro "IPR004173".
- 3H_domain name "3.0".
- 3H_domain pfam "PF02829".
- 3H_domain prosite "PDOC00449".
- 3H_domain scop "1.57788E8".
- 3H_domain symbol "3.0".
- 3H_domain wikiPageUsesTemplate Template:Infobox_protein_family.
- 3H_domain wikiPageUsesTemplate Template:InterPro_content.
- 3H_domain wikiPageUsesTemplate Template:Orphan.
- 3H_domain wikiPageUsesTemplate Template:Reflist.
- 3H_domain subject Category:Protein_families.
- 3H_domain hypernym Domain.
- 3H_domain type Biomolecule.
- 3H_domain type Protein.
- 3H_domain type Chemical.
- 3H_domain type Thing.
- 3H_domain type Q206229.
- 3H_domain type Q8054.
- 3H_domain comment "In molecular biology, the 3H domain is a protein domain named after its three highly conserved histidine residues. The 3H domain appears to be a small molecule-binding domain, based on its occurrence with other domains. Several proteins carrying this domain are transcriptional regulators from the biotin repressor family. The transcription regulator TM1602 from Thermotoga maritima is a DNA-binding protein thought to belong to a family of de novo NAD synthesis pathway regulators.".
- 3H_domain label "3H domain".
- 3H_domain sameAs m.0gty9q_.
- 3H_domain sameAs Q4636352.
- 3H_domain sameAs Q4636352.
- 3H_domain wasDerivedFrom 3H_domain?oldid=589766224.
- 3H_domain depiction PDB_1j5y_EBI.jpg.
- 3H_domain isPrimaryTopicOf 3H_domain.